ChemicalBook > Product Catalog >Chemical Reagents >Organic reagents >Esters >Other esters >2(5H)-Furanone
2(5H)-Furanone
- CAS No.
- 497-23-4
- Chemical Name:
- 2(5H)-Furanone
- Synonyms
- FURANONE;FURAN-2(5H)-ONE;Butenolide;γ-Crotonolactone;2-Furanone;4-Hydroxy-2-butenoic acid gamma-lactone;CARMELAN;2-Butenolide;Crotonolactone;2H-furan-5-one
- CBNumber:
- CB3201475
- Molecular Formula:
- C4H4O2
- Molecular Weight:
- 84.07
- MOL File:
- 497-23-4.mol
- Modify Date:
- 2024/7/23 18:28:04
| Melting point | 4-5 °C (lit.) |
|---|---|
| Boiling point | 86-87 °C/12 mmHg (lit.) |
| Density | 1.185 g/mL at 25 °C (lit.) |
| FEMA | 4138 | 4-HYDROXY-2-BUTENOIC ACID GAMMA-LACTONE |
| refractive index |
n |
| Flash point | 214 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform, Ethyl Acetate (Slightly) |
| form | Liquid |
| color | Clear colorless to pale yellow or amber |
| Odor | buttery |
| Odor Type | buttery |
| Water Solubility | Immiscible with water. |
| JECFA Number | 2000 |
| BRN | 383585 |
| Stability | Moisture Sensitive |
| InChIKey | VIHAEDVKXSOUAT-UHFFFAOYSA-N |
| LogP | -0.600 |
| CAS DataBase Reference | 497-23-4(CAS DataBase Reference) |
| NIST Chemistry Reference | 2(5H)-Furanone(497-23-4) |
| EPA Substance Registry System | 2(5H)-Furanone (497-23-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P280a-P305+P351+P338-P321-P332+P313-P337+P313-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | LU3453000 | |||||||||
| F | 8-10 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 29322980 | |||||||||
| NFPA 704 |
|
2(5H)-Furanone price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 283754 | 2(5H)-Furanone 98% | 497-23-4 | 1G | ₹4362.48 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 283754 | 2(5H)-Furanone 98% | 497-23-4 | 5G | ₹20545.85 | 2022-06-14 | Buy |
| TCI Chemicals (India) | C1078 | γ-Crotonolactone min. 93.0 % | 497-23-4 | 5ML | ₹10700 | 2022-05-26 | Buy |
| TCI Chemicals (India) | C1078 | γ-Crotonolactone min. 93.0 % | 497-23-4 | 25ML | ₹20600 | 2022-05-26 | Buy |
| ottokemi | F 1895 | 2(5H)-Furanone 98% | 497-23-4 | 1gm | ₹4005 | 2022-05-26 | Buy |
2(5H)-Furanone Chemical Properties,Uses,Production
Chemical Properties
2(5H)-Furanone is light brown liquid
Occurrence
Reported found in coffee
Uses
2(5H)-Furanone is a versatile reagent used in Michael addition reactions1 for synthesis of lignans.2 Also employed in three-component Michael-Aldol reactions with an aldehyde anda thiolate3 or carbanion.4
Definition
2(5H)-Furanone is a mycotoxin that contains an α,β-unsaturated lactone moiety.
General Description
Chiral urea compounds catalyzed hetero-Michael addition reaction of 2(5H)-furanone (γ-crotonolactone) to pyrrolidine. The quorum sensing inhibition activity by 2(5H)-furanone was studied using bioindicator strains.
Hazard
Extremely toxic.
Purification Methods
Fractionally distil the lactone under reduced pressure. IR: (CCl4) 1784 and 1742 cm-1, UV no max above 205nm ( 1160 cm-1 M-1) and 1HR: (CCl3) : 2.15 (pair of triplets 1H), 3.85 (pair of triplets 1H) and 5.03 (triplet 2H). [Price & Judge Org Synth Coll Vol V 255 1973, Smith & Jones Can J Chem 37 2007, 2092 1959, Beilstein 17/9 V 112.]
2(5H)-Furanone Preparation Products And Raw materials
Raw materials
Preparation Products
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Global( 252)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Otto Chemie Pvt Ltd | +91-2222070099 +91-2266382599 | Maharashtra, India | 429 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| TSK Lifesciences | 91-9397306789 | Hyderabad, India | 246 | 58 | Inquiry |
| Santo Righello Pvt. Ltd | 91-9885571757 | Hyderabad, India | 919 | 58 | Inquiry |
| Chaturya Biotech (Tanuj Life Sciences) | 91-7702707258 | Hyderabad, India | 399 | 58 | Inquiry |
| 5 E Scientific | 91-22-28016026 | Maharashtra, India | 137 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Otto Chemie Pvt Ltd | 58 |
| CHEMSWORTH | 30 |
| A.J Chemicals | 58 |
| Otto Chemie Pvt. Ltd. | 58 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| Alfa Aesar | 58 |
| TSK Lifesciences | 58 |
| Santo Righello Pvt. Ltd | 58 |
| Chaturya Biotech (Tanuj Life Sciences) | 58 |
| 5 E Scientific | 58 |
497-23-4(2(5H)-Furanone)Related Search:
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.alpha.,.beta.-Crotonolactone
γ-Crotonolactone, 2-Buten-1,4-olide
2,5-Dihydrofuranone
5-Oxo-2,5-dihydrofuran-3-yl ester
a,b-Crotonolactone
Crotonic acid, 4-hydroxy-
2,5-Dihydrofuran-2-one
2(5H)-Furanone,γ-Crotonolactone, 2-Buten-1,4-olide
.gamma.-Hydroxycrotonicacidlactone
.gamma.-Crotolactone
.delta.,.alpha.,.beta.-Butenolide
but-2-en-4-olide
2(5H)-Furanone 98%
2(5H)-FURANONE FOR SYNTHESIS 1 ML
2(5H)-Furanone
2-Oxo-2,5-dihydrofuran
2(5H)-Furanone (.gamma.-crotonolactone)
AKOS BBS-00003279
GAMMA-CROTONOLACTONE
2-Butenoic acid, 4-hydroxy-, gamma-lactone
2-Butenoic acid-gamma-lactone
2-Butenoicacid,4-hydroxy-,.gamma.-lactone
2-Butenoicacid.gamma.-lactone
2-butenoicacidgamma-lactone
2-Oxo-2,5-dihydrofuran(2-[5H]-furanone)
4-Hydroxy-2-butenoic acid lactone
4-Hydroxy-2-butenoicacid.gamma.-lactone
4-hydroxy-2-butenoicacidgamma-lactone
4-Hydroxy-2-butenoicacidlactone
4-hydroxy-2-butenoicacigamma-lactone
4-hydroxy-crotonicacigamma-lactone
5H-Furan-2-one
alpha,beta-Crotonolactone
Crotonic acid, 4-hydroxy-, gamma-lactone
Crotonicacid,4-hydroxy-,.gamma.-lactone
delta,alpha,beta-Butenolide
gamma-Crotolactone
gamma-Hydroxycrotonic acid lactone
gamma-hydroxycrotonicacidlactone
Isocrotonolactone
2-BUTEN-1,4-OLIDE
2-OXO-2,5-DIHYDROFURAN
2(5H)-FURANONE
2,5-DIHYDRO-2-FURANONE
2(5H)-Furanone,98%
5-HYDROFURAN-2-ONE
2-Buten-1,4-olide~gamma-Crotonolactone
g-Crotonolactone
γ-Crotonolactone>
2(5H)-Furanone 497-23-4
2-Furanone
FURAN-2(5H)-ONE
FURANONE
CARMELAN
2-Buten-4-olide
2-Butenolide
4-Hydroxy-2-butenoic acid gamma-lactone
Butenolide
Crotonolactone