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ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Cytoskeletal Signaling >HSP e.g. HSP90 inhibitors >17-DMAG

17-DMAG

17-DMAG Structure
CAS No.
467214-21-7
Chemical Name:
17-DMAG
Synonyms
KOS 1022;BMS 826476;Risatriptan;BMS 826476 HCl;AlvespiMycin HCl;MK 462 free base;17-DMAG USP/EP/BP;KOS-1022 hydrochloride;Spiramycin hydrochloride;17-DMAG (AlvespiMycin) HCl
CBNumber:
CB3469563
Molecular Formula:
C32H49ClN4O8
Molecular Weight:
653.21
MOL File:
467214-21-7.mol
Modify Date:
2024/7/2 8:55:06
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17-DMAG Properties

storage temp. Store at -20
solubility ≥26.2 mg/mL in DMSO; insoluble in EtOH; ≥3.04 mg/mL in H2O
form Purple solid
color Purple to purplish red
InChIKey KUFRQPKVAWMTJO-LMZWQJSESA-N

SAFETY

Risk and Safety Statements

HS Code  2941900000

17-DMAG price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 100069 17-DMAG - CAS 467214-21-7 - Calbiochem A potent antitumor analog of 17-AAG that binds to the ATPase site of human Hsp90α with high affinity and displays excellent bioavailability and aqueou 467214-21-7 500μG ₹32230 2022-06-14 Buy
Product number Packaging Price Buy
100069 500μG ₹32230 Buy

17-DMAG Chemical Properties,Uses,Production

Uses

17-DMAG is an analogue of Gelamycin (G304500) and 17-(Allylamino)geldanamycin (A549650). 17-DMAG acts as a Hsp90 inhibitor and displays more potent antitumor activity than 17-AAG.

Enzyme inhibitor

This potent Hsp90 inhibitor (FWHCl-Salt = 653.21 g/mol; CAS 467214-21-7), also named 17-DMAG and 17-demethoxy-17-[[2-(dimethylamino) ethyl]amino]geldanamycin, targets Heat Shock Protein-90 (IC50 = 62 nM in a cell-free assay). (See also Ansamycin; Deguelin; Derrubone; Ganetespib; Geldanamycin; Herbimycin; Macbecin; Radicicol; Tanespimycin; and the nonansamycin Hsp90 inhibitor KW-2478)

17-DMAG Preparation Products And Raw materials

Raw materials

Preparation Products

17-DMAG Suppliers

Global( 97)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Shaanxi Haibo Biotechnology Co., Ltd +undefined18602966907 China 1000 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 25859 58 Inquiry
Baoji Guokang Bio-Technology Co., Ltd. 0917-3909592 13892490616 China 9325 58 Inquiry
BOC Sciences 16314854226; +16314854226 United States 19743 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Hefei TNJ Chemical Industry Co.,Ltd. 0551-65418684 +8618949823763 China 25363 58 Inquiry
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd +8618829768577 China 1250 58 Inquiry
Supplier Advantage
Shaanxi Haibo Biotechnology Co., Ltd 58
ATK CHEMICAL COMPANY LIMITED 60
Career Henan Chemica Co 58
Dideu Industries Group Limited 58
Baoji Guokang Bio-Technology Co., Ltd. 58
BOC Sciences 58
Zhejiang J&C Biological Technology Co.,Limited 58
InvivoChem 58
Hefei TNJ Chemical Industry Co.,Ltd. 58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd 58

467214-21-7(17-DMAG)Related Search:

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Alvespimycin Acetylspiramycin Spiramycin Bortezomib Imatinib mesylate
Nilotinib Artesunate Luminespib 17-AAG Geldanamycin
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17-DIMETHYLAMINOETHYLAMINO-17-DEMETHOXY-GELDANAMYCIN 17-DIMETHYLAMINOGELDANAMYCIN Alvespimycin hydrochloride BMS 826476 KOS 1022 AlvespiMycin hydrochloride(17-DMAG,BMS 826476 17-DMAG HCl (AlvespiMycin) 17-DMAG (AlvespiMycin) HCl AlvespiMycin HCl Geldanamycin, 17-demethoxy-17-[[2-(dimethylamino)ethyl]amino]-, monohydrochloride NSC 707545,BMS 826476 HCl,KOS 1022 17-DMAG - CAS 467214-21-7 - Calbiochem Alvespimycin Hydrochloride (17-DMAG Hydrochloride Alvespimycin (17-DMAG) hydrochloride KOS-1022 hydrochloride Alvespimycin (17-DMAG) HCl 17DMAG; NSC 707545; KOS-1022; BMS 826476 HCL;KOS 1022 BMS 826476 HCl Geldanamycin 17-N-(2-Dimethylaminoethylamino) 17-DMAG hydrochloride (Alvespimycin) 17-DMAG USP/EP/BP MK 462 free base Risatriptan 17-DMAG Hydrochloride Salt Alvespimycin Spiramycin hydrochloride 17-DMAG hydrochloride (Avespimycin) BMS 826476|||NSC 707545|||KOS-1022|||17-DMAG hydrochloride|||Alvespimycin (17-DMAG) HCl 467214-21-7 C32H48N4O8 Inhibitors Anti-cancer&immunity