Imazalil
- CAS No.
- 35554-44-0
- Chemical Name:
- Imazalil
- Synonyms
- ENILCONAZOLE;Eniloconazol;ENICONAZOLE;chloramizole;1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole;MAZAL;r23979;Magnate;R 23979;FLO-PRO
- CBNumber:
- CB4251497
- Molecular Formula:
- C14H14Cl2N2O
- Molecular Weight:
- 297.18
- MOL File:
- 35554-44-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:08
| Melting point | 52.7°C |
|---|---|
| Boiling point | >340°C |
| Density | 1.348 |
| vapor pressure | 1.58 x l0-4 Pa (20 °C) |
| refractive index | 1.5680 (estimate) |
| storage temp. | 2-8°C |
| solubility | Chloroform: Slightly Soluble; Methanol: Slightly Soluble |
| pka | 6.53 (weak base) |
| form | Solid |
| color | Light yellow to yellow |
| Water Solubility | 0.018 g/100 mL |
| Merck | 13,3616 |
| BRN | 545683 |
| InChIKey | PZBPKYOVPCNPJY-UHFFFAOYSA-N |
| LogP | 3.820 |
| CAS DataBase Reference | 35554-44-0(CAS DataBase Reference) |
| NIST Chemistry Reference | Imazalil(35554-44-0) |
| EPA Substance Registry System | Imazalil (35554-44-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS05,GHS06,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H318-H332-H410 | |||||||||
| Precautionary statements | P261-P273-P280-P301+P310-P304+P340+P312-P305+P351+P338 | |||||||||
| Hazard Codes | Xn,N | |||||||||
| Risk Statements | 20/22-41-50/53 | |||||||||
| Safety Statements | 26-39-60-61 | |||||||||
| RIDADR | 2588 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | NI4776000 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29332900 | |||||||||
| NFPA 704 |
|
Imazalil Chemical Properties,Uses,Production
Description
Imazalil is an imidazole fungicide that inhibits ergosterol biosynthesis. Imazalil inhibits the growth of various fungi in vitro including P. italicum, A. niger, U. maydis, B. alii, and C. cucumerinum in a pH-dependent manner (MICs = 0.005-2 μg/ml at pH 7). It inhibits S. cerevisiae, but not rat liver microsomal, cytochrome P450 enzymes (CYPs; IC50s = 0.088 and 80 μM, respectively), as well as aromatase CYP19 from human placental microsomes (IC50 = 0.34 μM). Imazalil activates the murine pregnane X receptor (PXR) in a concentration-dependent manner in a cell-based reporter assay. It increases hepatic CYP3A11 and CYP2B10 mRNA levels in mice when administered at a dose of 100 mg/kg. Imazalil also increases Ki-67-positive nuclei in liver sections and hepatic MCM2 mRNA levels, markers of cell proliferation, in mice when co-administered with the murine constitutive androstane receptor (mCAR) agonist TCPOBOP . Formulations containing imazalil have been used to control fungal infection in agriculture.
Uses
Imazalil is a systemic fungicide with protective and curative action. It is used for the control of a wide range of fungal diseases on fruit, vegetables and ornamentals, powdery mildew on roses and storage diseases of citrus fruit, pome fruit, bananas and seed potatoes. It is also used as a seed dressing, for control of diseases of cereals (particularly Fusarium and Helminthosporium spp.), and it is particularly active against benzimidazole-resistant strains of plant-pathogenic fungi.
General Description
Slightly yellow to brown solidified oil. Non-corrosive. Used as a fungicide.
Air & Water Reactions
Water soluble.
Reactivity Profile
Imazalil is an imidazole derivative.
Safety Profile
Poison by ingestion and intraperitoneal routes. Experimental reproductive effects. A skin and eye irritant. When heated to decomposition it emits toxic fumes of Cland NOx.
Metabolic pathway
Published information is available on the metabolism of imazalil in plants and soils. The principal metabolite in plants and soils is 1-[2-(2,4- dichlorophenyl)-2-hydroxyethyl]-1H-imidazole.
Imazalil Preparation Products And Raw materials
Raw materials
1of3
chevron_rightPreparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Hebei Yanxi Chemical Co., Ltd. | +86-17531190177; +8617531190177 | China | 5873 | 58 | Inquiry |
| airuikechemical co., ltd. | +undefined86-15315557071 | China | 983 | 58 | Inquiry |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | China | 3002 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21667 | 55 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29888 | 58 | Inquiry |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | China | 8821 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49392 | 58 | Inquiry |
35554-44-0(Imazalil)Related Search:
1of4
chevron_right