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Trifluoromethanesulfonyl chloride

Trifluoromethanesulfonyl chloride  Structure
CAS No.
421-83-0
Chemical Name:
Trifluoromethanesulfonyl chloride
Synonyms
TRIFLYL CHLORIDE;PFC-MSC;Trifluoromethane chloride;TRIFLUOROMETHANESULFONYLCLORIDE;trifluoromethylsulfonyl chloride;Trifluoromethanesufonyl chloride;RIFLUOROMETHANESULFONYL CHLORIDE;Trifluoromathanesulfonyl chloride;TRIFLUOROMETHANESULFONYL CHLORIDE;Trifluoromethylsulphonyl chloride
CBNumber:
CB4253800
Molecular Formula:
CClF3O2S
Molecular Weight:
168.52
MOL File:
421-83-0.mol
MSDS File:
SDS
Modify Date:
2024/6/15 22:11:33

Trifluoromethanesulfonyl chloride Properties

Melting point -26 °C
Boiling point 29-32 °C (lit.)
Density 1.583 g/mL at 25 °C (lit.)
vapor pressure 10.36 psi ( 20 °C)
refractive index n20/D 1.334(lit.)
Flash point 32°C
storage temp. 2-8°C
solubility Chloroform
form Liquid
color Clear colorless to faintly colored
Specific Gravity 1.583
Water Solubility Hydrolyzes with water.
Sensitive Lachrymatory
BRN 1812016
InChIKey GRGCWBWNLSTIEN-UHFFFAOYSA-N
CAS DataBase Reference 421-83-0(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405
Hazard Codes  C
Risk Statements  14-34
Safety Statements  26-36/37/39-45
RIDADR  UN 3265 8/PG 2
WGK Germany  3
10-21
Hazard Note  Corrosive/Lachrymatory
HazardClass  8
PackingGroup  II
HS Code  29049090
NFPA 704
1
3 2
W

Trifluoromethanesulfonyl chloride price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 164798 Trifluoromethanesulfonyl chloride ≥99% 421-83-0 5G ₹4156.7 2022-06-14 Buy
Sigma-Aldrich(India) 164798 Trifluoromethanesulfonyl chloride ≥99% 421-83-0 25G ₹14643.4 2022-06-14 Buy
TCI Chemicals (India) T1027 Trifluoromethanesulfonyl Chloride min. 98.0 % 421-83-0 5G ₹5000 2022-05-26 Buy
TCI Chemicals (India) T1027 Trifluoromethanesulfonyl Chloride min. 98.0 % 421-83-0 25G ₹14800 2022-05-26 Buy
Product number Packaging Price Buy
164798 5G ₹4156.7 Buy
164798 25G ₹14643.4 Buy
T1027 5G ₹5000 Buy
T1027 25G ₹14800 Buy

Trifluoromethanesulfonyl chloride Chemical Properties,Uses,Production

Chemical Properties

Clear colorless to faintly colored liquid

Uses

Ru(II) complex-catalyzed trifluoromethylating agent for aromatics and alkenes.

Application

Trifluoromethanesulfonyl chloride can be used as:
A trifluoromethylating agent for the fluoroalkylation of heterocycles, arenes, and heteroarenes.
A sulfonating agent for alcohols.
A chlorinating agent for carbanions.

Synthesis

Add 150g (1mol) of trifluoromethanesulfonic acid to the reactor equipped with thermometer, distillation device and mechanical stirrer, slowly add 435mL (6mol) of thionyl chloride under ice bath, and then add the catalyst N,N-dimethyl Formamide 7.36 (0.1 mol), slowly raise the temperature to room temperature, stir for half an hour, continue to heat up to 40°C, continue to stir, react for 12 hours, and then drop to room temperature after the reaction is complete.Subsequently, vacuum distillation was carried out at 110° C. and -0.1 to -0.08 MPa, and at the same time, the temperature was slowly raised to 50° C. to obtain 147 g of trifluoromethanesulfonyl chloride, with a yield of 87.5%. TRIFLUOROMETHANESULFONYL CHLORIDE

Global( 278)Suppliers
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TRIFLUOROMETHANESULFONYL CHLORIDE TRIFLUOROMETHANESULPHONYL CHLORIDE Methanesulfonyl chloride, trifluoro- PFC-MSC Trifluoromathanesulfonyl chloride Trifluoromethanesulphonylchloride,99% trifluoromethylsulfonyl chloride Trifluoromethanesulphonyl chloride 99% TRIFLUOROMETHANESULFONYLCLORIDE TRIFLUOROMETHANESULFONYL CHLORIDE, 99+% Trifluoromethanesulfonylchloride,98% Trifluoromethylsulphonyl chloride Trifluoromethanesulfonic acid chloride Trifluoromethanesufonyl chloride Trifluoromethylsulphonyl chloride 99% TriMethylsilyltrilfluoroMethanesulfonate TrifluoroMethanesulfonyl chloride, 99% 25GR TRIFLUOROMETHANESULFONYL CHLORIDE FOR SY Three fluorineMethane sulfonyl chloride Trifluoromethanesulfonyl chloride, 99.5% trifluoromethanesulfonyl chloride CClF3O2S Trifluoromethane chloride Trifluoromethanesulfonyl chloride, 98%, for synthesis TRIFLYL CHLORIDE RIFLUOROMETHANESULFONYL CHLORIDE Trifluoromethanesulfonyl Chloride, ≥ 98.0% 421-83-0 421-86-0 CClF3O2S CF3SO2Cl C3F4l2 CF3ClO2S CClF3SO2 Protection and Derivatization Protecting and Derivatizing Reagents Others Synthetic Reagents Piperazine derivates organofluorine compounds Others Protecting and Derivatizing Reagents Protection and Derivatization