GSK-3β Inhibitor XVIII
- CAS No.
- 1139875-74-3
- Chemical Name:
- GSK-3β Inhibitor XVIII
- Synonyms
- GSK3β-IN-1a;GSK3β-IN-1a;GSK-3β inhibitor 8;GSK3β Inhibitor XVIII;GSK-3β Inhibitor XVIII;GSK-3β Inhibitor XVIII - CAS 1139875-74-3 - Calbiochem;2-chloro-4-[[4-(2-thienyl)-2-pyrimidinyl]amino]phenyl](4-methyl-1-piperazinyl)-,methanone;Methanone, [2-chloro-4-[[4-(2-thienyl)-2-pyrimidinyl]amino]phenyl](4-methyl-1-piperazinyl)-
- CBNumber:
- CB52602508
- Molecular Formula:
- C20H20ClN5OS
- Molecular Weight:
- 413.92
- MOL File:
- 1139875-74-3.mol
- Modify Date:
- 2024/7/2 8:55:11
GSK-3β Inhibitor XVIII price More Price(1)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 361562 | GSK-3β Inhibitor XVIII - CAS 1139875-74-3 - Calbiochem The GSK-3β Inhibitor XVIII, also referenced under CAS 1139875-74-3, controls the biological activity of GSK-3β. This small molecule/inhibitor is prima | 1139875-74-3 | 5MG | ₹14260 | 2022-06-14 | Buy |
| Product number | Packaging | Price | Buy |
|---|---|---|---|
| 361562 | 5MG | ₹14260 | Buy |
GSK-3β Inhibitor XVIII Chemical Properties,Uses,Production
Description
GSK3β inhibitor XVIII is an inhibitor of glycogen synthase kinase 3β (GSK3β; IC50 = 64 nM). It induces expression of a luciferase reporter in HEK293 cells expressing wild-type Wnt (EC50 = ~1.25 μM) but not in cells expressing a β-catenin/TCF binding site-mutant Wnt. GSK3β inhibitor XVIII increases β-catenin accumulation in the nucleus of HEK293 cells. It induces proliferation of R7T1 β-cells (EC50 = 1,143 nM), an effect that can be blocked by the COX and Wnt signaling inhibitor sulindac , and rat primary β-cells.
GSK-3β Inhibitor XVIII Preparation Products And Raw materials
Raw materials
Preparation Products
GSK-3β Inhibitor XVIII Suppliers
Global( 17)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Riedel-de Haen AG | 800 558-9160 | United States | 6825 | 87 | Inquiry |
| Shanghai Hao Biological Technology Co., Ltd. | 021-58116080 18019263206 | CHINA | 6921 | 58 | Inquiry |
| Morning Student Science and Technology (Guangzhou) Co., Ltd. | 020-36048871 13760856740 | CHINA | 6618 | 58 | Inquiry |
| Absin Bioscience Inc. | 021-38015121 | CHINA | 6661 | 58 | Inquiry |
| Boao Pike | 010-57798038 15652371397 | CHINA | 6629 | 58 | Inquiry |
| Shanghai Hao Zhun Biological Technology Co., Ltd. | 15800340161 | CHINA | 6846 | 58 | Inquiry |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | China | 11289 | 58 | Inquiry |
| Cayman Chemical Company | (800) 364-9897 | United States | 6618 | 81 | Inquiry |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | China | 9708 | 58 | Inquiry |
| TargetMol Chemicals Inc. | 4008200310 | China | 24017 | 58 | Inquiry |
1139875-74-3(GSK-3β Inhibitor XVIII)Related Search:
GSK-3β Inhibitor XVIII
GSK-3β Inhibitor XVIII - CAS 1139875-74-3 - Calbiochem
GSK3β-IN-1a
GSK3β Inhibitor XVIII
Methanone, [2-chloro-4-[[4-(2-thienyl)-2-pyrimidinyl]amino]phenyl](4-methyl-1-piperazinyl)-
GSK3β-IN-1a
2-chloro-4-[[4-(2-thienyl)-2-pyrimidinyl]amino]phenyl](4-methyl-1-piperazinyl)-,methanone
GSK-3β inhibitor 8
1139875-74-3