ChemicalBook > Product Catalog >Organic Chemistry >Phosphines >2-Dicyclohexylphosphino-2'-(N,N-dimethylamino)biphenyl
2-Dicyclohexylphosphino-2'-(N,N-dimethylamino)biphenyl
- CAS No.
- 213697-53-1
- Chemical Name:
- 2-Dicyclohexylphosphino-2'-(N,N-dimethylamino)biphenyl
- Synonyms
- DAVEPHOS;2-(N,N-Dimethylamino)-2-(dicyclohexylphosphino)biphenyl;N-[2'-(dicyclohexylphosphino)-1,1'-biphenyl-2-yl]-N,N-diMethylaMine;Davep;2-(Dicycloh;98% DavePhos;DavePhos 97%;phosphino-2'-(N,N-dimethyL;2-Dicyclohexylphosphino-2'-(N,;2-DICYCLOHEXYLPHOSPHINO-2'-(N,N-DIMETHY&
- CBNumber:
- CB6344872
- Molecular Formula:
- C26H36NP
- Molecular Weight:
- 393.54
- MOL File:
- 213697-53-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/12/13 16:54:32
| Melting point | 121-124 °C(lit.) |
|---|---|
| Boiling point | 539.6±43.0 °C(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| pka | 5.04±0.18(Predicted) |
| form | crystal |
| color | white |
| Water Solubility | Insoluble |
| Sensitive | Air Sensitive |
| InChIKey | ZEMZPXWZVTUONV-UHFFFAOYSA-N |
| CAS DataBase Reference | 213697-53-1(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-22 | |||||||||
| Safety Statements | 26-36/37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | No | |||||||||
| HazardClass | AIR SENSITIVE | |||||||||
| HS Code | 29310099 | |||||||||
| NFPA 704 |
|
2-Dicyclohexylphosphino-2'-(N,N-dimethylamino)biphenyl price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 638021 | DavePhos 97% | 213697-53-1 | 1G | ₹13290 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 638021 | DavePhos 97% | 213697-53-1 | 5G | ₹35720 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 638021 | DavePhos 97% | 213697-53-1 | 25G | ₹100834.88 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 638021 | DavePhos 97% | 213697-53-1 | 100G | ₹456717.58 | 2022-06-14 | Buy |
| TCI Chemicals (India) | D3389 | 2-(Dicyclohexylphosphino)-2'-(dimethylamino)biphenyl min. 98.0 % | 213697-53-1 | 1G | ₹8800 | 2022-05-26 | Buy |
2-Dicyclohexylphosphino-2'-(N,N-dimethylamino)biphenyl Chemical Properties,Uses,Production
Description
2-Dicyclohexylphosphino-2'-(N,N-dimethylamino)biphenyl is a potent inhibitor of the enzyme bromodomain. Bromodomain has been implicated in cancer and other diseases. It binds to the bromodomain in a covalent manner, blocking the ATP site and inhibiting bromodomain function. This inhibition has been shown to be selective for bromodomains over other domains.
Chemical Properties
white to light yellow crystals or
Uses
2-Dicyclohexylphosphino-2'-(N,N-dimethylamino)biphenyl can act as ligand used in the palladium-catalyzed Suzuki coupling and amination of unactivated aryl chlorides.
Application
2-Dicyclohexylphosphino-2'-(N,N-dimethylamino)biphenylacts as a growth regulator by binding to Toll-like receptor 4 (TLR4), which is important in cytokine signaling. It also inhibits allyl carbonate production and cross coupling reactions between aryl chlorides and nitrogen atoms or amines. It has an inhibitory effect on depression, but this effect is not related to its inhibitory effect on bromodomains.
2-Dicyclohexylphosphino-2'-(N,N-dimethylamino)biphenyl Preparation Products And Raw materials
Raw materials
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Global( 352)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Reax Chemicals | 08048372701Ext 416 | Hyderabad, India | 4223 | 58 | Inquiry |
| Mehta Enterprise | 08068442230Ext 607 | Mumbai, India | 155 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| XINXIANG RUNYU MATERIAL CO., LTD. | +86-13592593621; +8613592593621 | China | 432 | 58 | Inquiry |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | China | 7121 | 58 | Inquiry |
| Springchem New Material Technology Co.,Limited | +86-021-62885108 +8613917661608 | China | 2068 | 57 | Inquiry |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
| Supplier | Advantage |
|---|---|
| A.J Chemicals | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| Reax Chemicals | 58 |
| Mehta Enterprise | 58 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| Alfa Aesar | 58 |
| XINXIANG RUNYU MATERIAL CO., LTD. | 58 |
| Shanghai UCHEM Inc. | 58 |
| Springchem New Material Technology Co.,Limited | 57 |
| Capot Chemical Co.,Ltd. | 60 |
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2-DICYCLOHEXYLPHOSPHINO-2'-(N,N-DIMETHY&
2-(DICYCLOHEXYLPHOSPHINO)-2'-(DIMETHYLAMINO)BIPHENYL
2-DICYCLOHEXYLPHOSPHINO-2'-(N,N-DIMETHYLAMINO)BIPHENYL
2-Dicyclohexylphosphino-2'-(N,
2-(Dicyclohexylphosphino)-2'-(N,N-dimethylamino)biphenyl,98%DavePhos
2-Dicyclohexylphosphino-2'-(N,N-dimethylamino)-
[1,1''-BIPHENYL]-2-AMINE, 2''-(DICYCLOHEXYLPHOSPHINO)-N,N-DIMETHYL-
2-Dicgclohexylphosphino-2’-(N,N-dimethylamino)biphenyl
Davep
2-Dicyclohexylphosphino-2'-(N,N-dimethylamino)biphenyl,97%
2-Dicyclohexylphosphino-2-(N,N-dimethylamino)biphenyl,98%
2-Dicyclohexylphosphino-2-(N,N-dimethylamino)biphenyl（Davephos）
2-Dicyclohexylphosphino-2-(N,N-dimethylamino)biph
2-[2-(dicyclohexylphosphanyl)phenyl]-N,N-diMethylaniline
Davephos (2-(Di-tert-butylphosphino)biphenyl)
98% DavePhos
2-DicyclohexylphosphiNA-2'-(N,N-diMethylaMiNA)biphenyl
2'-(dicyclohexylphosphino)-N,N-diMethyl-[1,1'-biphenyl]-2-aMine
2-(Dicyclohexylphosphanyl)-2'-(dimethylamino)biphenyl
2'-(Dicyclohexylphosphanyl)-N,N-dimethylbiphenyl-2-amine, Dicyclohexyl[2'-(dimethylamino)biphenyl-2-yl]phosphine
DavePhos 97%
2-(N,N-Dimethylamino)-2-(dicyclohexylphosphino)biphenyl, DavePhos
2-(Dicyclohexylphosphino)-2'-(N,N-dimethylamino))-1,1'-biphenyl, 98%
2-Dimethylamino-2'-dicyclohexylphosphinobiphenyl
2-(Dicyclohexylphosphino)-2'-(N,N-dimethylamino))-1,1'-biphenyl, 98% DavePhos
2-Dicyclohexylphosphino-2'-(N,N-dimethylamino)bipheny
2-(Dicycloh
2-(Dicyclohexylphosphino)-2'-(N,N-dimethylamino)biphenyl,98%DavePh
phosphino-2'-(N,N-dimethyL
2-(Dicyclohexylphosphino)-2'-(dimethylamino)biphenyl>
2-(Dicyclohexylphosphino)-2'-(N,N-dimethylamino))-1,1'-biphenyl,98%
DavePhos 2-Dicyclohexylphosphino-2'-(N,N-dimethylamino)biphenyl
2-Dicyclohexylphosphino-2-(N,N-dimethyiamino)-1,1'-biphenyl
213697-53-1 2-Dicyclohexylphosphino-2'-(N,N-dimethylamino)biphenyl‘ 213697-53-1
DAVEPHOS
2-(N,N-Dimethylamino)-2-(dicyclohexylphosphino)biphenyl
N-[2'-(dicyclohexylphosphino)-1,1'-biphenyl-2-yl]-N,N-diMethylaMine
(2-Dimethylamino-1,1'-biphenyl-2-yl)dicyclohexylphosphine
2-Dicyclohexyphenyl-2 '- (N, N-dimethylamine) - biphenyl
2-Dicyclohexylphosphino-2'-(N,N-dimethylamino)biphenyl
2'-(Dicyclohexylphosphino)-N,N-dimethyl-[1,1'-biphenyl]-2-amine
(2-Dimethylamino-1,1'-biphenyl-2-yl)dicyclohexylphosphine
2'-(dicyclohexylphosphanyl)-N,N-dimethyl-[1,1'-biphenyl]-2-amine
2-(Dicyclohexylphosphino)-2'-(N,N-dimethylamino)biphenyl,DavePhos
213697-53-1
CH32NC6H4C6H4PC6H112
C26H36NP
Catalysis and Inorganic Chemistry
Buchwald Ligands
Phosphorus Compounds
Phosphine Ligands
Buchwald Ligands&Precatalysts
Achiral Phosphine
Aryl Phosphine
Buchwald Ligands Series
Phosphines
Biphenyl & Diphenyl ether
Phosphine Ligands