ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Neuronal Signaling >COX inhibitors >Tolfenamic acid
Tolfenamic acid
- CAS No.
- 13710-19-5
- Chemical Name:
- Tolfenamic acid
- Synonyms
- CLOTAM;gea6414;Tolfedine;Tolfenamic;olfenamicaci;Toxamic acid;Tofenamic acid;TOLFENAMIC ACID;TOLEFNAMIC ACID;Tolfenamic acid CRS
- CBNumber:
- CB6365693
- Molecular Formula:
- C14H12ClNO2
- Molecular Weight:
- 261.7
- MOL File:
- 13710-19-5.mol
- Modify Date:
- 2024/12/18 14:08:57
| Melting point | 210-214°C |
|---|---|
| Boiling point | 405.4±40.0 °C(Predicted) |
| Density | 1.2037 (rough estimate) |
| refractive index | 1.5270 (estimate) |
| storage temp. | 2-8°C |
| solubility | Practically insoluble in water, soluble in dimethylformamide, sparingly soluble in ethanol and in methylene chloride. It dissolves in dilute solutions of alkali hydroxides. |
| form | Solid |
| pka | 3.66±0.36(Predicted) |
| color | White to Off-White |
| Water Solubility | Soluble in water (slightly), acetone (~10 mg/ml), DMSO (52 mg/ml at 25°C), methanol (~10 mg/ml) and ethanol (50 mg/ml). |
| Merck | 14,9513 |
| InChIKey | YEZNLOUZAIOMLT-UHFFFAOYSA-N |
| CAS DataBase Reference | 13710-19-5(CAS DataBase Reference) |
| EPA Substance Registry System | Benzoic acid, 2-[(3-chloro-2-methylphenyl)amino]- (13710-19-5) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301 | |||||||||
| Precautionary statements | P264-P270-P301+P310-P405-P501 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | CB2687500 | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29224919 | |||||||||
| NFPA 704 |
|
Tolfenamic acid price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | T0535 | Tolfenamic acid NSAID | 13710-19-5 | 5G | ₹8227 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR1629 | Tolfenamic Acid Pharmaceutical Secondary Standard; Certified Reference Material | 13710-19-5 | 500MG | ₹9201.25 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 34073 | Tolfenamic acid VETRANAL?, analytical standard | 13710-19-5 | 100MG | ₹10749.23 | 2022-06-14 | Buy |
| TCI Chemicals (India) | C2064 | Tolfenamic Acid | 13710-19-5 | 25G | ₹7600 | 2022-05-26 | Buy |
Tolfenamic acid Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
Tolfenamic acid is a non-steroidal anti-inflammatory agent. It interferes with synthesis of β-amyloid precursor protein, and thus Aβ peptides, by promoting degradation of an essential transcription factor. It inhibits fMLP- and A23187-induced Ca2+ influx in human PMNL with an IC50 value of approximately 20 μM.
Definition
ChEBI: An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 3-chloro-2-methylphenyl group. Tolfenamic acid is used specifically for relieving the pain of migraine. It also shows anticancer activity.
General Description
Tolfenamic Acid is an anthranilic acid derivative and a non-steroidal anti-inflammatory drug (NSAID). Its applications in treating pancreatic, esophageal, colorectal and lung cancer is being investigated.
Tolfenamic acid Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 290)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Mehta Pharmaceutical Industries | +91-8390068777 +91-8390068777 | Mumbai, India | 30 | 58 | Inquiry |
| SUJALAM CHEMICALS | +91-9422560788 +91-9422560788 | Maharashtra, India | 42 | 58 | Inquiry |
| Siddhivinayakchemicals | +91-912225190111 +91-9819773074 | Mumbai, India | 42 | 58 | Inquiry |
| Nira Life Sciences Pvt Ltd | +91-2751240480 +91-9924781287 | Gujarat, India | 4 | 58 | Inquiry |
| Anlon Healthcare Pvt Ltd | +91-2812562538 +91-7069690081 | Gujarat, India | 54 | 58 | Inquiry |
| Precise Biopharma Pvt Ltd | +91-2267828600 +91-2267828600 | Maharashtra, India | 46 | 58 | Inquiry |
| Sindhu Organics Pvt Ltd | +91-9833086472 +91-9820087786 | Maharashtra, India | 3 | 58 | Inquiry |
| Diligent Life Care | +91-2262515000 +91-9898023247 | Gujarat, India | 12 | 58 | Inquiry |
| Parmax Pharma Limited | +91-9924544911 +91-9428003765 | Gujarat, India | 31 | 58 | Inquiry |
| Medilink Pharmachem | +91 (79) 3007-0133 | New Delhi, India | 424 | 50 | Inquiry |
| Supplier | Advantage |
|---|---|
| Mehta Pharmaceutical Industries | 58 |
| SUJALAM CHEMICALS | 58 |
| Siddhivinayakchemicals | 58 |
| Nira Life Sciences Pvt Ltd | 58 |
| Anlon Healthcare Pvt Ltd | 58 |
| Precise Biopharma Pvt Ltd | 58 |
| Sindhu Organics Pvt Ltd | 58 |
| Diligent Life Care | 58 |
| Parmax Pharma Limited | 58 |
| Medilink Pharmachem | 50 |
13710-19-5(Tolfenamic acid)Related Search:
chevron_left
1of4
chevron_right
LABOTEST-BB LT00772313
TOLFENAMIC ACID
2-((3-chloro-2-methylphenyl)amino)-benzoicaci
gea6414
n-(2-methyl-3-chlorophenyl)anthranilicacid
2-(3-CHLORO-O-TOLUIDINO)BENZOIC ACID
2 (3-CHLORO-2-METHYLANILINO)BENZOIC ACID
2-[(3-CHLORO-2-METHYLPHENYL)AMINO]BENZOIC ACID
2-[(3-Chloro-2-methylphenyl)amino]benzoic Acid
2-(3-Chloro-o-toluidino)benzoic Acid
Tolfenamic Acid
Tolfenamic acid Solution, 100ppm
2 (3-Chloro-2-methylanilino)benzoic acid, 2-([3-Chloro-2-methylphenyl]amino)benzoic acid
2-[(4-Chloro-3-methylphenyl)amino]benzoic acid
Tolfedine
2-[(3-Chloro-o-tolyl)amino]benzoic acid
n-(3-chloro-o-tolyl)-anthranilicaci
CLOTAM
n-(3-chloro-o-tolyl)-anthranilicacid
N-(3-CHLORO-2-METHYLPHENYL)ANTHRANILIC ACID
n-(3-chloro-ortho-tolyl) anthranilic acid
Tolfenamic
Benzoic acid, 2-(3-chloro-2-methylphenyl)amino-
N-(3-Chloro-ortho-tolyl) anthranilic acid solution,100ppm
Tolfenamic Acid:2-((3-Chloro-2-methylphenyl)amino)benzoic acid
Tolfenamic Acid Standard
N-(3-Chloro-2-methylphenyl)anthranilic Acid >
Tolfenamic acid CRS
Tolfenamic acid USP/EP/BP
Tolfenamic Acid (GEA 6414)
N-(3-Chloro-ortho-tolyl) anthranilic acid 13710-19-5
olfenamicaci
TOLEFNAMIC ACID
Tofenamic acid
Toxamic acid
C17591000 TolfenamiCacid
Tolfenamic acid 100 μg/ml Acetonitrile
Tolfenamic Acid, 10 mM in DMSO
13710-19-5
13710-19-1
Enzyme Inhibitors by Type
Enzyme Inhibitors
Enzymes, Inhibitors, and Substrates
Substrate Analogs
BioChemical
Biochemicals and Reagents
CLOTAM
Amines
Aromatics
Intermediates & Fine Chemicals
Pharmaceuticals
Active Pharmaceutical Ingredients