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Amoxicillin trihydrate

Amoxicillin trihydrate Structure
CAS No.
61336-70-7
Chemical Name:
Amoxicillin trihydrate
Synonyms
AMOXYCILLIN TRIHYDRATE;AMOXICILIN TRIHYDRATE;Amoxicillin trihydrate for performance verification CRS;Am 7;Amodex;A-Gram;Ardine;PeniMox;HelvaMox;AmoxiciL
CBNumber:
CB6690306
Molecular Formula:
C16H21N3O6S
Molecular Weight:
383.42
MOL File:
61336-70-7.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:14

Amoxicillin trihydrate Properties

Melting point >200°C (dec.)
alpha D20 +246° (c = 0.1)
refractive index 302 ° (C=0.1, H2O)
storage temp. Inert atmosphere,2-8°C
solubility Slightly soluble in water, very slightly soluble in ethanol (96 per cent), practically insoluble in fatty oils. It dissolves in dilute acids and dilute solutions of alkali hydroxides.
form Solid
color White to Off-White
Water Solubility Soluble in water at 3.4mg/ml.
Merck 14,577
JECFA Number 85
BRN 7507120
CAS DataBase Reference 61336-70-7(CAS DataBase Reference)
EPA Substance Registry System Amoxicillin trihydrate (61336-70-7)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08
Signal word  Danger
Hazard statements  H317-H334
Precautionary statements  P261-P272-P280-P284-P302+P352-P333+P313
Hazard Codes  Xn,Xi
Risk Statements  42/43
Safety Statements  36-36/37-22
WGK Germany  2
RTECS  XH8300000
HS Code  29411000
Toxicity LD50 ipr-rat: 2870 mg/kg KSRNAM 7,3040,73

Amoxicillin trihydrate price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) PHR1127 Amoxicillin trihydrate Pharmaceutical Secondary Standard; Certified Reference Material 61336-70-7 1G ₹8995.58 2022-06-14 Buy
Sigma-Aldrich(India) 31586 Amoxicillin trihydrate VETRANAL?, analytical standard 61336-70-7 250MG ₹7382.65 2022-06-14 Buy
TCI Chemicals (India) A2099 Amoxicillin Trihydrate 61336-70-7 5G ₹3000 2022-05-26 Buy
TCI Chemicals (India) A2099 Amoxicillin Trihydrate 61336-70-7 25G ₹9500 2022-05-26 Buy
SRL 24645 Amoxicillin Trihydrate (AMOT), 97% 61336-70-7 1Gms ₹300 2022-05-26 Buy
Product number Packaging Price Buy
PHR1127 1G ₹8995.58 Buy
31586 250MG ₹7382.65 Buy
A2099 5G ₹3000 Buy
A2099 25G ₹9500 Buy
24645 1Gms ₹300 Buy

Amoxicillin trihydrate Chemical Properties,Uses,Production

Description

Amoxicillin was synthesized by Beecham Research Laboratories in 1968. A hydroxyl group was introduced on the benzene ring of ampicillin. Amoxicillin shows about a twofold higher serum concentration than ampicillin when administered orally. It was shown by double-blind comparative studies with ampicillin that amoxicillin was as effective as ampicillin when administered at half the dose of ampicillin.

Chemical Properties

White to Off-White Solid

Uses

Amoxicillin trihydratesemi-synthetic antibiotic related to Penicillin which has antibacterial poperties. It is used for treatment of a variety of bacterial infections. It is used as a pharmaceutical product as a antibiotic agent, anti-infective drug raw materials.

Definition

ChEBI: A hydrate that is the trihydrate form of amoxicillin; a semisynthetic antibiotic, used either alone or in combination with potassium clavulanate (under the trade name Augmentin) for treatment of a variety of bacterial infections.

Contact allergens

Amoxicillin is both a topical and a systemic sensitizer. Topical sensitization occurs in health care workers. Systemic drug reactions are frequent, such as urticaria, maculo-papular rashes, baboon syndrome, acute generalized exanthematous pustulosis, or even toxic epidermal necrosis. Cross-reactivity is common with ampicillin, and can occur with other penicillins.

Safety Profile

Moderately toxic. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of SOx and NOx.

Amoxicillin trihydrate Preparation Products And Raw materials

Global( 583)Suppliers
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Asiatic Drugs And Pharmaceuticals Pvt Ltd +91-1126412720 +91-1141616836 New Delhi, India 2 58 Inquiry
Unimark Remedies Ltd +91-2267304120 +91-2267304120 Maharashtra, India 48 58 Inquiry
Syschem (India) Limited +91-7340783755 +91-8968433155 Haryana, India 8 58 Inquiry

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