Amoxicillin trihydrate
![Amoxicillin trihydrate Structure](CAS/GIF/61336-70-7.gif)
- CAS No.
- 61336-70-7
- Chemical Name:
- Amoxicillin trihydrate
- Synonyms
- AMOXYCILLIN TRIHYDRATE;AMOXICILIN TRIHYDRATE;Amoxicillin trihydrate for performance verification CRS;Am 7;Amodex;A-Gram;Ardine;PeniMox;HelvaMox;AmoxiciL
- CBNumber:
- CB6690306
- Molecular Formula:
- C16H21N3O6S
- Molecular Weight:
- 383.42
- MOL File:
- 61336-70-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:14
Melting point | >200°C (dec.) |
---|---|
alpha | D20 +246° (c = 0.1) |
refractive index | 302 ° (C=0.1, H2O) |
storage temp. | Inert atmosphere,2-8°C |
solubility | Slightly soluble in water, very slightly soluble in ethanol (96 per cent), practically insoluble in fatty oils. It dissolves in dilute acids and dilute solutions of alkali hydroxides. |
form | Solid |
color | White to Off-White |
Water Solubility | Soluble in water at 3.4mg/ml. |
Merck | 14,577 |
JECFA Number | 85 |
BRN | 7507120 |
CAS DataBase Reference | 61336-70-7(CAS DataBase Reference) |
EPA Substance Registry System | Amoxicillin trihydrate (61336-70-7) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS08 |
---|---|
Signal word | Danger |
Hazard statements | H317-H334 |
Precautionary statements | P261-P272-P280-P284-P302+P352-P333+P313 |
Hazard Codes | Xn,Xi |
Risk Statements | 42/43 |
Safety Statements | 36-36/37-22 |
WGK Germany | 2 |
RTECS | XH8300000 |
HS Code | 29411000 |
Toxicity | LD50 ipr-rat: 2870 mg/kg KSRNAM 7,3040,73 |
Amoxicillin trihydrate price More Price(7)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | PHR1127 | Amoxicillin trihydrate Pharmaceutical Secondary Standard; Certified Reference Material | 61336-70-7 | 1G | ₹8995.58 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 31586 | Amoxicillin trihydrate VETRANAL?, analytical standard | 61336-70-7 | 250MG | ₹7382.65 | 2022-06-14 | Buy |
TCI Chemicals (India) | A2099 | Amoxicillin Trihydrate | 61336-70-7 | 5G | ₹3000 | 2022-05-26 | Buy |
TCI Chemicals (India) | A2099 | Amoxicillin Trihydrate | 61336-70-7 | 25G | ₹9500 | 2022-05-26 | Buy |
SRL | 24645 | Amoxicillin Trihydrate (AMOT), 97% | 61336-70-7 | 1Gms | ₹300 | 2022-05-26 | Buy |
Amoxicillin trihydrate Chemical Properties,Uses,Production
Description
Amoxicillin was synthesized by Beecham Research Laboratories in 1968. A hydroxyl group was introduced on the benzene ring of ampicillin. Amoxicillin shows about a twofold higher serum concentration than ampicillin when administered orally. It was shown by double-blind comparative studies with ampicillin that amoxicillin was as effective as ampicillin when administered at half the dose of ampicillin.
Chemical Properties
White to Off-White Solid
Uses
Amoxicillin trihydratesemi-synthetic antibiotic related to Penicillin which has antibacterial poperties. It is used for treatment of a variety of bacterial infections. It is used as a pharmaceutical product as a antibiotic agent, anti-infective drug raw materials.
Definition
ChEBI: A hydrate that is the trihydrate form of amoxicillin; a semisynthetic antibiotic, used either alone or in combination with potassium clavulanate (under the trade name Augmentin) for treatment of a variety of bacterial infections.
Contact allergens
Amoxicillin is both a topical and a systemic sensitizer. Topical sensitization occurs in health care workers. Systemic drug reactions are frequent, such as urticaria, maculo-papular rashes, baboon syndrome, acute generalized exanthematous pustulosis, or even toxic epidermal necrosis. Cross-reactivity is common with ampicillin, and can occur with other penicillins.
Safety Profile
Moderately toxic. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of SOx and NOx.
Amoxicillin trihydrate Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
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