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2-Fluoroaniline

2-Fluoroaniline Structure
CAS No.
348-54-9
Chemical Name:
2-Fluoroaniline
Synonyms
2-fluroaniline;O-FLUOROANILINE;2-Fluorobenzenamine;AKOS 91139;2-Fluoranilin;FLUOROANILINE-2;2-FLUOROANILINE;AKOS BBS-00003628;1BO-Fluoroaniline;Aniline, o-fluoro-
CBNumber:
CB6853530
Molecular Formula:
C6H6FN
Molecular Weight:
111.12
MOL File:
348-54-9.mol
MSDS File:
SDS
Modify Date:
2023/12/22 17:53:22

2-Fluoroaniline Properties

Melting point -29 °C
Boiling point 182-183 °C(lit.)
Density 1.151 g/mL at 25 °C(lit.)
vapor pressure 1 hPa (20 °C)
refractive index n20/D 1.544(lit.)
Flash point 140 °F
storage temp. Store below +30°C.
solubility 17g/l
pka 3.2(at 25℃)
form Liquid
color Clear colorless
Specific Gravity 1.151
Water Solubility 17 g/L (20°C)
BRN 1524219
CAS DataBase Reference 348-54-9(CAS DataBase Reference)
NIST Chemistry Reference Benzenamine, 2-fluoro-(348-54-9)
EPA Substance Registry System o-Fluoroaniline (348-54-9)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS05,GHS07,GHS08,GHS09
Signal word  Danger
Hazard statements  H226-H302-H314-H373-H410
Precautionary statements  P210-P273-P280-P303+P361+P353-P305+P351+P338-P314
Hazard Codes  Xn,T,Xi
Risk Statements  22-37/38-41-36/38-33-23/24/25
Safety Statements  26-39-37/39-45-36/37-28
RIDADR  UN 2941 6.1/PG 3
WGK Germany  2
RTECS  BY1390000
Autoignition Temperature 600 °C
Hazard Note  Toxic/Irritant
TSCA  T
HazardClass  6.1
PackingGroup  III
HS Code  29214210
NFPA 704
2
2 0

2-Fluoroaniline price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) F3401 2-Fluoroaniline ≥99% 348-54-9 25G ₹4827.95 2022-06-14 Buy
Sigma-Aldrich(India) F3401 2-Fluoroaniline ≥99% 348-54-9 100G ₹8237.83 2022-06-14 Buy
Sigma-Aldrich(India) F3401 2-Fluoroaniline ≥99% 348-54-9 500G ₹31814.68 2022-06-14 Buy
Sigma-Aldrich(India) 8.20565 2-Fluoroaniline for synthesis 348-54-9 100ML ₹13550 2022-06-14 Buy
TCI Chemicals (India) F0032 2-Fluoroaniline min. 99.0 % 348-54-9 25G ₹2000 2022-05-26 Buy
Product number Packaging Price Buy
F3401 25G ₹4827.95 Buy
F3401 100G ₹8237.83 Buy
F3401 500G ₹31814.68 Buy
8.20565 100ML ₹13550 Buy
F0032 25G ₹2000 Buy

2-Fluoroaniline Chemical Properties,Uses,Production

Chemical Properties

2-Fluoroaniline is a clear colorless to brown liquid, toxic, insoluble in water, soluble in ethanol and ether, its vapor and air can form an explosive mixture, which can cause combustion and explosion in case of fire and high heat. Reacts with oxidants. Decomposed by high heat to release toxic gases.

Uses

2-Fluoroaniline (cas# 348-54-9) is a useful reagent for the synthesis of insecticides.

Definition

ChEBI: 2-fluoroaniline is a derivative of aniline in which the hydrogen at position 2 has been substituted by fluorine. It is used as a pharmaceutical intermediate It is a primary arylamine and a fluoroaniline.

General Description

Clear liquid with a mild sweet odor. Sinks in and mixes slowly with water.

Air & Water Reactions

Water soluble.

Reactivity Profile

2-Fluoroaniline is a base. Neutralizes acids to form salts plus water in an exothermic reaction. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Health Hazard

Inhalation or ingestion causes bluish tint to fingernails, lips and ears indicative of cyanosis; headache, drowsiness, and nausea, followed by unconsciousness. Liquid can be absorbed through skin and cause similar symptoms. Contact with eyes causes irritation.

Fire Hazard

Special Hazards of Combustion Products: Irritating and toxic hydrogen fluoride and oxides of nitrogen may form in fires.

Metabolic pathway

2-Fluoro and 3-fluoroanilines are preferentially hydroxylated at the para-position, and 4-fluoroaniline is both p- and o-hydroxylated to a significant extent by rat liver microsomes and is not accompanied with an NIH shift to give 4-hydroxyl-3-fluoroaniline.

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LABOTEST-BB LTBB000714 FLUOROANILINE-2 2-Fluoroaniline o-Fluoroaniline 2-FLUOROANILINE, 99+% 2-FluoroanilineForSynthesis 2-Fluoroaniline99.5% Aniline, 2-fluoro- Aniline, o-fluoro- 1,2-fluorobenzenamine 2-fluoro-benzenamin 2-fluoro-Benzenamine 2-Fluoro-phenylamine 2-Fluoroaniline, 97+% 2-FLUOROANILINE 2-Fluoranilin Benzenamine, 2-fluoro- 1-AMINO-2-FLUOROBENZENE AKOS 91139 AKOS BBS-00003628 Telmisartan Impurity 13 4-chlorobenzoic acid [8-[[4-[4-[[3-[(4-chlorophenyl)-oxomethoxy]-8-methyl-8-azoniabicyclo[3.2.1]octan-8-yl]methyl]phenyl]phenyl]methyl]-8-methyl-8-azoniabicyclo[3.2.1]octan-3-yl] ester dibromide 1BO-Fluoroaniline 2-Fluoroaniline> 2-Aminofluorobenzene 2-Fluoroaniline ISO 9001:2015 REACH 2-Fluoroaniline pure, 98% 2-fluroaniline 2-Fluorobenzenamine O-FLUOROANILINE Telmisartan Impurity U Abemaciclib Impurity 10 348-54-9 48-54-9 348-59-9 FC6H4NH2 C2 to C6 Building Blocks Amines Organic Building Blocks Nitrogen Compounds Fluoro-Aromatics Anilines, Aromatic Amines and Nitro Compounds Fluorobenzene Heterocyclic Compounds Benzene derivatives Fluorobenzene Series Fluorine series amine | alkyl Fluorine