ChemicalBook > Product Catalog >Biochemical Engineering >Polypeptide >Felypressin

Felypressin

Felypressin Structure
CAS No.
56-59-7
Chemical Name:
Felypressin
Synonyms
PLV-2;FELYPRESSIN;Octapressin;Felipresina;Phelypressin;Felypressin CRS;Felypressin Acetate;[PHE2,LYS8]-VASOPRESSIN;Pharmaceuticals Felypressin;M.W. 1040.22 C46H65N13O11S2
CBNumber:
CB7729324
Molecular Formula:
C46H65N13O11S2
Molecular Weight:
1040.22
MOL File:
56-59-7.mol
Modify Date:
2024/7/2 8:55:17

Felypressin Properties

Melting point >197oC (dec.)
Boiling point 1571.3±65.0 °C(Predicted)
Density 1.288±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility Freely soluble in water, practically insoluble in acetone and ethanol (96 per cent). It dissolves in dilute solutions of alkali hydroxides.
pka 12.82±0.70(Predicted)
form Solid
color White
Sequence H-[Cys-Phe-Phe-Gln-Asn-Cys]-Pro-Lys-Gly-NH2,(Disulfide bridge: Cys-Cys)
CAS DataBase Reference 56-59-7(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

WGK Germany  3

Felypressin Chemical Properties,Uses,Production

Chemical Properties

White or almost white, powder or flakes

Uses

Felypressin(Octapressin) is a vasopressin 1 agonist and a peptide containing eight amino acids including cystine. Felypressin is used as a vasoconstrictor.

Definition

ChEBI: A synthetic nonapeptide comprising cysteinyl, phenylalanyl, phenylalanyl, glutaminyl, asparaginyl, cysteinyl, prolyl, lysyl, and glycinamide residues in sequence, with a disulfide bridge joining the two cysteine residues. Its antidiuretic effects are less han those of vasopressin. It is used as a vasoconstrictor in local anaesthetic injections for dental use, and is an ingredient of preparations that have been used for treatment of pain and inflammation of the mouth.

General Description

Felypressin, 2-L-phenylalanine-8-L-lysinevasopressin, has relatively low antidiuretic activity and littleoxytocic activity. It has considerable pressor (i.e., vasoconstrictor)activity, which differs from that of epinephrine (i.e.,following capillary constriction in the intestine it lowers thepressure in the vena portae, whereas epinephrine raises theportal pressure). Felypressin also causes increased renalblood flow in the cat, whereas epinephrine brings about afall in renal blood flow. Felypressin is five times more effectiveas a vasopressor than is lysine vasopressin and is recommendedin surgery to minimize blood flow, especially inobstetrics and gynecology.

Felypressin Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 156)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Zibo Hangyu Biotechnology Development Co., Ltd +86-0533-2185556 +8617865335152 China 10978 58 Inquiry
Nantong Guangyuan Chemicl Co,Ltd +undefined17712220823 China 616 58 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21669 55 Inquiry
Hangzhou FandaChem Co.,Ltd. 008657128800458; +8615858145714 China 9337 55 Inquiry
Shenzhen Nexconn Pharmatechs Ltd +86-755-89396905 +86-15013857715 China 10318 58 Inquiry
Cellmano Biotech Limited 0551-65326643 18156095617 China 999 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-29-87569266 15319487004 China 4088 58 Inquiry
FELYPRESSIN H-CYS-PHE-PHE-GLN-ASN-CYS-PRO-LYS-GLY-NH2, CYS1,6, CYCLIC [PHE2,LYS8]-VASOPRESSIN 2-L-Phenylalanine-8-L-lysine-vasopressin N-[5-Amino-1-(carbamoylmethylcarbamoyl)pentyl]-1-[19-amino-13,16-dibenzyl-10-(2-carbamoylethyl)-7-(carbamoylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide Octapressin Phelypressin PLV-2 2-(phenylalanine)-8-lyine vasopression M.W. 1040.22 C46H65N13O11S2 (2-L-Phenylalanine)-8-lysinevasopressin 2-(Phenylalanine)-8-lysine vasopressin L-Cys(1)-L-Phe-L-Phe-L-Gln-L-Asn-L-Cys(1)-L-Pro-L-Lys-Gly-NH2 Felypressin Acetate 1-[16-amino-4-(2-amino-2-keto-ethyl)-7-(3-amino-3-keto-propyl)-10,13-bis(benzyl)-3,6,9,12,15-pentaketo-18,19-dithia-2,5,8,11,14-pentazacycloicosane-1-carbonyl]-N-[5-amino-1-[(2-amino-2-keto-ethyl)carbamoyl]pentyl]pyrrolidine-2-carboxamide N-[6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl]-1-[16-amino-4-(2-amino-2-oxoethyl)-7-(3-amino-3-oxopropyl)-3,6,9,12,15-pentaoxo-10,13-bis(phenylmethyl)-18,19-dithia-2,5,8,11,14-pentazacycloicosane-1-carbonyl]pyrrolidine-2-carboxamide N-[6-azanyl-1-[(2-azanyl-2-oxo-ethyl)amino]-1-oxo-hexan-2-yl]-1-[[16-azanyl-4-(2-azanyl-2-oxo-ethyl)-7-(3-azanyl-3-oxo-propyl)-3,6,9,12,15-pentaoxo-10,13-bis(phenylmethyl)-18,19-dithia-2,5,8,11,14-pentazacycloicos-1-yl]carbonyl]pyrrolidine-2-carboxamide 2,3-Bis(phenylalanine)-8-lysineoxytocin H-Cys-Phe-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 acetate salt (Disulfide bond) Felypressin,Felipresina, Octapressin Felypressin CRS H-[Cys-Phe-Phe-Gln-Asn-Cys]-Pro-Lys-Gly-NH2 Vasopressin, 2-L-phenylalanine-8-L-lysine- Pharmaceuticals Felypressin Felipresina Felypressin Acetate/Felypressin 56-59-7 C46H64O9N12S2 C46H65N13O11S2 Inhibitors Amino Acids & Derivatives Intermediates & Fine Chemicals Pharmaceuticals Vasopressin and Oxytocin receptor