Indigo Carmine
- CAS No.
- 860-22-0
- Chemical Name:
- Indigo Carmine
- Synonyms
- INDIGOTINE;CI 73015;Indigo Carmine,pure,certified;E132;73015;Was35;l-blau2;murabba;1311blue;Greell S
- CBNumber:
- CB8231484
- Molecular Formula:
- C16H11N2NaO8S2
- Molecular Weight:
- 446.38
- MOL File:
- 860-22-0.mol
- Modify Date:
- 2023/4/23 13:52:06
| Melting point | >300°C |
|---|---|
| Density | 1.01 g/mL at 20 °C |
| refractive index | n20/D 1.335 |
| storage temp. | room temp |
| solubility | 1g/l |
| Colour Index | 73015 |
| form | Powder/Solid |
| color | Very dark blue to purple |
| PH Range | 11.5(blue)-14.0(yellow) |
| Odor | Light odour |
| PH | 7 (10g/l, H2O, 20℃) |
| Water Solubility | 1 g/100 mL (25 ºC) |
| Sensitive | Light Sensitive |
| λmax | 608nm |
| Merck | 14,4944 |
| BRN | 4103904 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Biological Applications | Detecting microorganisms; treating amyloidosis,testicular cancer; medical devices; drug delivery system |
| Major Application | Display device, sensor, chemical-mechanical polishing, batteries, photographic materials, thermoplastics, inks, highlighters, detergents, disinfectants, rodenticide, colored bubbles, hair dyes, cosmetics, food, determine bacterial growth, antiischemic Magents, antiseptic, antitumor agents, Alzheimer’s disease, psychoactive drugs, Tooth whitening |
| LogP | -3.57 |
| CAS DataBase Reference | 860-22-0(CAS DataBase Reference) |
| EPA Substance Registry System | C.I. Acid Blue 74 (860-22-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H317 | |||||||||
| Precautionary statements | P261-P272-P280-P302+P352-P333+P313-P362+P364 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 22-24/25-36/37/39-27-26 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | DU3000000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 32041200 | |||||||||
| Toxicity | LD50 orally in Rabbit: > 2000 mg/kg | |||||||||
| NFPA 704 |
|
Indigo Carmine price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 57000 | Indigo carmine for microscopy (Bact., Hist.), indicator (pH 11.5-14.0) | 860-22-0 | 25G | ₹4051.5 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 57000 | Indigo carmine for microscopy (Bact., Hist.), indicator (pH 11.5-14.0) | 860-22-0 | 100G | ₹7903.2 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 73436 | Indigo carmine analytical standard | 860-22-0 | 25MG | ₹16738.8 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 57000 | Indigo carmine for microscopy (Bact., Hist.), indicator (pH 11.5-14.0) | 860-22-0 | 500G | ₹51404.1 | 2022-06-14 | Buy |
| Sigma-Aldrich | 131164 | Indigo carmine certified by the Biological Stain Commission, Dye content 85?% | 860-22-0 | 25G | ₹2075.7 | 2022-06-14 | Buy |
Indigo Carmine Chemical Properties,Uses,Production
Description
Indigo carmine is indigotindisulfonate sodium, a marker dye used during cystoscopy and ureteral catheterization.
(1) Indigo carmine is also used in endoscopic procedures, lymph node and vessel delineation, and for tumor localization. Indigo carmine is an unapproved drug without FDA approved labeling.
(2) There is no single dye that can replace indigo carmine. Choice of alternative agent will depend on type of procedure and physician discretion, as well as product availability.
Indigo Carmine (IC) is the most common chemical dye for clothes dyeing, which is considered as a refractory molecule since it is required a rather strong chemical treatment for its elimination from the water waste. The presence of this dye in residuals causes notorious change of water color and smell even in very low concentration. Moreover, if some of this water reaches natural streams it can be toxic for aquatic living entities due to the formation of toxic compounds such as aromatic amines.
Chemical Properties
purple powder
Uses
Indigo Carmine (FD&C Blue #2) is a colorant. It has poor ph stability in that after 1 week at ph 3 and 5 it will appreciably fade, at ph 7 considerably fade, and at ph 8 fade completely. It is the least soluble of all food colors, with a solubility of 1.6 g in 100 ml of water at 25°c. Complete fading occurs in alkalis such as 10% sodium carbonate and 10% sodium hydroxide, with fading also occurring in 10% sugar systems. It has very poor light stability and oxidation stability, and moderate stability to heat; it has a deep blue hue with poor tinctorial strength. It is the only food color that has good resistance to reducing agents, but has very poor compatibility with food components. The major use is in pet food, but it is also used in candies, confections, and baked goods. The common name is indigotine.
Preparation
3H-indol-3-one,2-(1,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,2-dihydro?with strong sulfuric acid or trace fuming sulfuric acid products.
Definition
ChEBI: An organic sodium salt resulting from the formal condensation of indigo carmine (acid form) with two equivalents of sodium hydroxide. It is an indicator at pH 11.5-14, changing from blue to yellow.
General Description
Indigo to dark blue powder.
Air & Water Reactions
Water soluble.
Reactivity Profile
Sensitive to light. Very sensitive to oxidizing agents. Color is readily discharged by nitric acid, chlorates, etc. Color of aqueous solutions fades on standing.
Fire Hazard
Flash point data for Acid Blue 74 is not available, but Acid Blue 74 is probably combustible.
Purification Methods
Its solubility in H2O is 1g/100mL at 25o. It has been purified by dissolving in H2O, filtering and adding EtOH to cause the salt to separate. Wash the solid with EtOH, Et2O and dry in vacuo. [V.rlander & Schubert Chem Ber 34 1860 1901, UV: Smit et al. Anal Chem 27 1159 1955, Preisler et al. J Am Chem Soc 81 1991 1959, Beilstein 25 IV 1975.]
References
American Society of Health-system Pharmacist.
Journal of Environmental Protection, 2016, 7, 1693-1706
Indigo Carmine Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Bhagwati Industries | +91-9909249884 +91-9909249884 | Gujarat, India | 89 | 58 | Inquiry |
| Dynemic Products Ltd. | +91-7927663071 +91-7927663071 | Gujarat, India | 64 | 58 | Inquiry |
| Arbuda Plastochem Pvt. Ltd | +91-9879005132 +91-9825069442 | Gujarat, India | 41 | 58 | Inquiry |
| Neelikon Food Dyes Chemicals Ltd | +91-7208901109 +91-9970004007 | Maharashtra, India | 30 | 58 | Inquiry |
| Orjet Intermediates Pvt. Ltd. | +91-9913616190 +91-9913616190 | Gujarat, India | 38 | 58 | Inquiry |
| Dishman Carbogen Amcis Ltd (Dishman Group) | +91-2717420100 +91-8154017093 | Gujarat, India | 90 | 58 | Inquiry |
| Standardcon Pvt. Ltd | +91-9323087138 +91-9323087138 | Maharashtra, India | 31 | 58 | Inquiry |
| Sun Food Tech | +91-9717799051 +91-9268579051 | New Delhi, India | 21 | 58 | Inquiry |
| Vidhi Specialty Food Ingredients Ltd | +91-2223514349 +91-2261406666 | Maharashtra, India | 17 | 58 | Inquiry |
| Tanya Exports | +91-9825040588 +91-9825033002 | Gujarat, India | 186 | 58 | Inquiry |
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