Aluminum hydroxide
- CAS No.
- 21645-51-2
- Chemical Name:
- Aluminum hydroxide
- Synonyms
- ALUMINIUM HYDROXIDE;ALUMINIUM HYDROXIDE GEL;ALUMINUM HYDROXIDE GEL;ALHYDROGEL;c33;ALUMINA HYDRATE;Aluminiumhydroxid;Aluminum hydroxide min;c4d;h46
- CBNumber:
- CB9243680
- Molecular Formula:
- AlH3O3
- Molecular Weight:
- 78
- MOL File:
- 21645-51-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/5 17:59:12
| Melting point | 300℃ |
|---|---|
| Boiling point | 2980℃[at 101 325 Pa] |
| Density | 2.42 g/cm3 at 20 °C |
| vapor pressure | <0.1 hPa (20 °C) |
| refractive index | Average refractive index: 1.57-1.59 |
| storage temp. | Store at +5°C to +30°C. |
| solubility | 0.0015g/l |
| form | colloidal suspension |
| Specific Gravity | 2.42 |
| color | White |
| Odor | Odorless |
| PH Range | >7 |
| PH | 8-9 (100g/l, H2O, 20℃)(slurry) |
| Water Solubility | insoluble |
| Crystal Structure | Monoclinic |
| Merck | 14,342 |
| Solubility Product Constant (Ksp) | pKsp: 32.89 |
| Exposure limits | ACGIH: TWA 1 mg/m3 |
| Dielectric constant | 2.2（Ambient） |
| Stability | Stable. Incompatible with strong bases. |
| LogP | -1.380 (est) |
| CAS DataBase Reference | 21645-51-2(CAS DataBase Reference) |
| EPA Substance Registry System | Aluminum hydroxide (21645-51-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | - | |||||||||
| RTECS | BD0940000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 28183000 | |||||||||
| Toxicity | TDLo oral in child: 79gm/kg/2Y-I | |||||||||
| NFPA 704 |
|
Aluminum hydroxide price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 239186 | Aluminum hydroxide reagent grade | 21645-51-2 | 25G | ₹4492.38 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 239186 | Aluminum hydroxide reagent grade | 21645-51-2 | 25G | ₹4492.38 | 2022-06-14 | Buy |
| Sigma-Aldrich | 239186 | Aluminum hydroxide reagent grade | 21645-51-2 | 500G | ₹6278.5 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 239186 | Aluminum hydroxide reagent grade | 21645-51-2 | 500G | ₹6278.5 | 2022-06-14 | Buy |
| Sigma-Aldrich | 239186 | Aluminum hydroxide reagent grade | 21645-51-2 | 2KG | ₹12535.35 | 2022-06-14 | Buy |
Aluminum hydroxide Chemical Properties,Uses,Production
Chemical Properties
Aluminum hydroxide, Al(OH)3, also known as aluminum trihydroxide, aluminum trihydrate, aluminum hydrate, hydrated alumina, and hydrated aluminum oxide, is a white to whitish-yellow water-insoluble powder with a specific gravity of 2.42. Aluminum hydroxide is used as a baseforpigments, as a water repellent in textile coatings, and as an antacid in medicine. Aluminum hydroxide is soluble in hydrochloric or sulfuric acids or in sodiumhydroxide.
Uses
aluminum hydroxide is an inorganic compound used to make a product less transparent. It is also used by formulators as a humectant, and to soften, smooth, and protect the skin. In addition it helps control product viscosity. often found in facial masks and make-up preparations.
Production Methods
Aluminum hydroxide adjuvant is prepared by the precipitation of a soluble aluminum salt by an alkali hydroxide, or the precipitation of an alkali aluminate by acid.
Pharmaceutical Applications
Aluminum hydroxide adjuvant is used in parenteral human and veterinary vaccines.It activates Th2 immune responses, including IgG and IgE antibody responses. It is also used for the isolation of certain serum components such as blood clotting factors.
Safety Profile
Poison by intraperitoneal route. Human systemic effects by ingestion: fever, osteomalacia, and gastrointestinal effects. When coprecipitated with bismuth hydroxide and reduced by H2, it is violently flammable in air. Incompatible with chlorinated rubber.
Safety
Aluminum hydroxide adjuvant is intended for use in parenteral vaccines and is generally regarded as nontoxic. It may cause mild irritation, dryness, and dermatitis on skin contact. On eye contact, aluminum hydroxide adjuvant may also cause redness, conjunctivitis, and short-term mild irritation. Ingestion of large amounts may cause gastrointestinal irritation with nausea, vomiting, and constipation. Inhalation of the dried product may cause respiratory irritation and cough. Type I hypersensitivity reactions following parenteral administration have been reported.
storage
Aluminum hydroxide adjuvant is stable for at least 2 years when stored at 4–308℃ in well-sealed inert containers. It must not be allowed to freeze as the hydrated colloid structure will be irreversibly damaged.
Incompatibilities
When exposed to phosphate, carbonate, sulfate, or borate anions, the point of zero charge for aluminum hydroxide adjuvant decreases.
Regulatory Status
GRAS listed. Accepted for use in human and veterinary parenteral vaccines in Europe and the USA. The limits for use in human vaccines are 0.85 mg aluminum/dose (FDA) and 1.25 mg aluminum/ dose (WHO). There are no established limits for use in veterinary vaccines. Reported in the EPA TSCA Inventory.
Aluminum hydroxide Preparation Products And Raw materials
Raw materials
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chevron_right| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| S.V ENTERPRISES | +919322701159 | Mumbai, India | 150 | 58 | Inquiry |
| UNILOSA INTERNATINAL PRIVATE LIMITED | +91-9999069917 +91-9999069917 | New Delhi, India | 152 | 58 | Inquiry |
| VITRAG CHEMICALS PVT LTD | +91-7490053194 +91-7490053194 | Gujarat, India | 47 | 58 | Inquiry |
| JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
| Agilenobel | +91-8090295395 +91-8800293647 | Haryana, India | 50 | 58 | Inquiry |
| Merck Ltd | +91-2262109800 +91-2262109000 | Maharashtra, India | 272 | 58 | Inquiry |
| Taurus Chemicals | +91-8458279503 +91-9849650702 | Telangana, India | 11 | 58 | Inquiry |
| Meha Chemicals | +91-9820048429 +91-9820048429 | Maharashtra, India | 28 | 58 | Inquiry |
| Nitika Pharmaceutical Specialities Pvt Ltd | +91-7122641001 +91-8956932443 | Maharashtra, India | 36 | 58 | Inquiry |
| Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| S.V ENTERPRISES | 58 |
| UNILOSA INTERNATINAL PRIVATE LIMITED | 58 |
| VITRAG CHEMICALS PVT LTD | 58 |
| JSK Chemicals | 58 |
| Agilenobel | 58 |
| Merck Ltd | 58 |
| Taurus Chemicals | 58 |
| Meha Chemicals | 58 |
| Nitika Pharmaceutical Specialities Pvt Ltd | 58 |
| Ralington Pharma | 58 |
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