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ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Pyridine compound >Dihydropyridine >ARRY-424704, ARRY-704

ARRY-424704, ARRY-704

ARRY-424704, ARRY-704 Structure
CAS No.
869357-68-6
Chemical Name:
ARRY-424704, ARRY-704
Synonyms
CS-396;ARRY704;AZD8330;ARRY-704;ARRY424704;ARRY-424704;AZD8330 (ARRY704;AZD8330 AZD-8330;AZD8330(ARRY-424704;ARRY-424704, ARRY-704
CBNumber:
CB82512518
Molecular Formula:
C16H17FIN3O4
Molecular Weight:
461.23
MOL File:
869357-68-6.mol
Modify Date:
2024/7/2 8:55:20
Request For Quotation

ARRY-424704, ARRY-704 Properties

Density 1.732
storage temp. Store at -20°C
solubility ≥23.05 mg/mL in DMSO; insoluble in H2O; ≥46.1 mg/mL in EtOH
form solid
pka 14.31±0.10(Predicted)
color Off-white to pink

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08,GHS06
Signal word  Danger
Hazard statements  H372-H301
Precautionary statements  P260-P264-P270-P314-P501-P264-P270-P301+P310-P321-P330-P405-P501
HS Code  2933998090
NFPA 704
0
2 0

ARRY-424704, ARRY-704 Chemical Properties,Uses,Production

Description

AZD 8330 is a selective allosteric inhibitor of MEK1/2 (IC50 = 7 nM). It blocks phosphorylation of ERK1/2 and inhibits proliferation of certain cancer cells. AZD 8330 is orally bioavailable, inhibits ERK phosphorylation in vivo, and reduces tumor growth in a Calu-6 nude rat xenograft model.

ARRY-424704, ARRY-704 Preparation Products And Raw materials

Raw materials

Preparation Products

ARRY-424704, ARRY-704 Suppliers

Global( 115)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CHEMSWORTH +91-261-2397244 New Delhi, India 6707 30 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29898 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
ANHUI WITOP BIOTECH CO., LTD +8615255079626 China 23556 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-029-89586680 +86-18192503167 China 9030 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Henan Aochuang Chemical Co.,Ltd. +86-0371-63689365 +8618638391208 China 9425 58 Inquiry
Supplier Advantage
CHEMSWORTH 30
ATK CHEMICAL COMPANY LIMITED 60
career henan chemical co 58
Chongqing Chemdad Co., Ltd 58
CONIER CHEM AND PHARMA LIMITED 58
ANHUI WITOP BIOTECH CO., LTD 58
Shaanxi Dideu Medichem Co. Ltd 58
Zhejiang J&C Biological Technology Co.,Limited 58
InvivoChem 58
Henan Aochuang Chemical Co.,Ltd. 58

ARRY-424704, ARRY-704 Spectrum

ARRY-424704, ARRY-704(869357-68-6)1HNMR

869357-68-6(ARRY-424704, ARRY-704)Related Search:

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Tozasertib R428 Nutlin 3a 6-[2-tert-Butyl-5-(6-methyl-pyridin-2-yl)-1H-imidazol-4-yl]-quinoxaline 6-Amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide
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ARRY-424704, ARRY-704 AZD8330 2-(2-Fluoro-4-iodophenylamino)-N-(2-hydroxyethoxy)-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxamide ARRY424704 ARRY-424704 ARRY704 ARRY-704 AZD8330/ARRY-424704/arry-704/AZD8330/AZD-8330 ARRY-424704, ARRY-704 AZD8330 AZD8330;ARRY-424704; ARRY424704;ARRY704; AZD8330 2-((2-Fluoro-4-iodophenyl)amino)-N-(2-hydroxyethoxy)-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3- CS-396 AZD8330(ARRY-424704 ARRY-424704; ARRY-704; AZD-8330; ARRY424704; ARRY704; AZD 8330 3-Pyridinecarboxamide, 2-[(2-fluoro-4-iodophenyl)amino]-1,6-dihydro-N-(2-hydroxyethoxy)-1,5-dimethyl-6-oxo- ARRY-424704, ARRY-704 ISO 9001：2015 REACH AZD8330 (ARRY704 AZD8330 AZD-8330 869357-68-6 C16H17FIN3O4 Inhibitors MAPK