ZLN005

ZLN005 Structure
CAS No.
49671-76-3
Chemical Name:
ZLN005
Synonyms
ZLN005;CS-1004;ZLN005, >=98%;ZLN 005; ZLN-005;2-(4-tert-Butylphenyl)benzimidazole;2-(4-tert-Butylphenyl)-1H-benzimidazole;2-(4-TERT-BUTYLPHENYL)-1H-BENZO[D]IMIDAZOLE;2-[4-(1,1-dimethylethyl)phenyl]-1H-benzimidazole;1H-Benzimidazole, 2-[4-(1,1-dimethylethyl)phenyl]-;2-(4-tert-Butylphenyl)benzimidazole ZLN005
CBNumber:
CB82681122
Molecular Formula:
C17H18N2
Molecular Weight:
250.34
MOL File:
49671-76-3.mol
MSDS File:
SDS
Modify Date:
2023/6/8 9:02:13

ZLN005 Properties

Melting point 257-258℃
Boiling point 415.3±38.0 °C(Predicted)
Density 1.102±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility DMSO: soluble10mg/mL, clear
pka 11.52±0.10(Predicted)
form powder
color white to beige

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H319-H413
Precautionary statements  P305+P351+P338
Hazard Codes  Xn
Risk Statements  22-36
Safety Statements  26
WGK Germany  3
NFPA 704
0
2 0

ZLN005 price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SML0802 ZLN005 ≥95% (HPLC) 49671-76-3 10MG ₹7144.5 2022-06-14 Buy
Sigma-Aldrich(India) SML0802 ZLN005 ≥95% (HPLC) 49671-76-3 50MG ₹28956.88 2022-06-14 Buy
Product number Packaging Price Buy
SML0802 10MG ₹7144.5 Buy
SML0802 50MG ₹28956.88 Buy

ZLN005 Chemical Properties,Uses,Production

Description

Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is a tissue-specific and inducible transcriptional coactivator for several nuclear receptors and plays a key role in energy metabolism, hepatic gluconeogenesis, and cholesterol homoeostasis. ZLN005 is a small molecule that stimulates the expression of PGC-1α and downstream genes in skeletal muscle cells, improving glucose utilization and fatty acid oxidation at a concentration of 20 μM. Chronic administration of 15 mg/kg/day ZLN005 to diabetic db/db mice increased PGC-1α and downstream gene transcription in skeletal muscle, increasing fat oxidation and improving glucose tolerance, pyruvate tolerance, and insulin sensitivity.

Uses

ZLN005 increaces PGC-1α and downstream gene transcription in skeletal muscles and increases fat oxidation and improved the glucose tolerance, pyruvate tolerance, and insulin sensitivity of diabetic db/db mice.

ZLN005 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 118)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29898 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Nanjing Doge Biomedical Technology Co., Ltd +86-25-58227606 +86-15305155328 China 4128 58 Inquiry
Coresyn Pharmatech Co., Ltd. +86-571-86626709 +86-18157142896 China 9991 58 Inquiry

ZLN005 Spectrum

2-(4-TERT-BUTYLPHENYL)-1H-BENZO[D]IMIDAZOLE 2-(4-tert-Butylphenyl)-1H-benzimidazole 2-(4-tert-Butylphenyl)benzimidazole ZLN005, >=98% 2-[4-(1,1-dimethylethyl)phenyl]-1H-benzimidazole 2-(4-tert-Butylphenyl)benzimidazole ZLN005 ZLN005 2-(4-tert-Butylphenyl)benzimidazole ZLN005 CS-1004 ZLN 005; ZLN-005 1H-Benzimidazole, 2-[4-(1,1-dimethylethyl)phenyl]- 49671-76-3 Inhibitors