Sodium danshensu
- CAS No.
- 67920-52-9
- Chemical Name:
- Sodium danshensu
- Synonyms
- NSC122009;NCI-C02120;NSC 122009;NSC-122009;dium danshensu;Sodium danshensu;DANSHENSU SODIUM (RG);Salvianic acid A sodium;(±)-DanShenSu sodium sal;Salvia natriuretic peptide
- CBNumber:
- CB91117913
- Molecular Formula:
- C9H11NaO5
- Molecular Weight:
- 222.17
- MOL File:
- 67920-52-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/11/19 23:02:33
Sodium danshensu Chemical Properties,Uses,Production
Description
Danshensu is a salvianolic acid and the major component of S. miltiorrhiza (Danshen) and has diverse biological activities. It reduces expression of the autophagy-associated proteins p62, LC3-II, and Beclin-1 and the apoptosis-related proteins Bax and caspase-3, prevents cardiomyocyte damage, and increases heart rate, coronary flow (CF), and left ventricular developed pressure (LVDP) in an isolated rat heart model of ischemia and reperfusion injury. Danshensu (60 mg/kg per day) reduces infarct size and improves left ventricular function in a rat model of myocardial infarction. It enhances radiation-induced tumor cell death in a Lewis lung carcinoma mouse xenograft model. Danshensu also decreases infarct volume, neuronal apoptosis, production of TNF-α, IL-1β, and IL-6, and superoxide dismutase (SOD) and glutathione peroxidase (GPx) activity in a rat model of cerebral ischemia and reperfusion injury.
Chemical Properties
White to light brown powder
Uses
Sodium Danshensu is exhibits protective effects on the excitotoxicity of monosodium glutamate in the late stage of pregnancy on developing mouse fetal brain.
Sodium danshensu Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
A.J Chemicals | 91-9810153283 | New Delhi, India | 6100 | 58 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29880 | 58 | Inquiry |
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | China | 3772 | 58 | Inquiry |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39894 | 58 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49374 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 32161 | 58 | Inquiry |
Hubei Ipure Biology Co., Ltd | +8613367258412 | China | 10319 | 58 | Inquiry |
Apeloa Pharmaceutical Co., Ltd. | +86-0571-87635730 +8615858229168 | China | 1478 | 58 | Inquiry |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | China | 23541 | 58 | Inquiry |
Baoji Guokang Bio-Technology Co., Ltd. | 0917-3909592 13892490616 | China | 9311 | 58 | Inquiry |
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