Cholic acid
![Cholic acid Structure](CAS/GIF/81-25-4.gif)
- CAS No.
- 81-25-4
- Chemical Name:
- Cholic acid
- Synonyms
- CA;CHOLATE;cholan-24-oic acid;3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid;3A,7A,12A-TRIHYDROXY-5B-CHOLAN-24-OIC ACID;(R)-4-((3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-diMethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid;CHOLALIN;Cholicaci;Cholic acd;CHOLIC ACID
- CBNumber:
- CB9263222
- Molecular Formula:
- C24H40O5
- Molecular Weight:
- 408.58
- MOL File:
- 81-25-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/21 22:41:43
Melting point | 200-201 °C (lit.) |
---|---|
Boiling point | 449.08°C (rough estimate) |
alpha | 36 º (c=0.6, 95% EtOH) |
Density | 1.0310 (rough estimate) |
refractive index | 1.5800 (estimate) |
Flash point | 9℃ |
storage temp. | 2-8°C |
solubility | methanol: 0.1 g/mL, clear |
pka | 4.98(at 20℃) |
form | Solid |
color | White to Brown |
Water Solubility | 0.28 g/L (15 ºC) |
Merck | 14,2203 |
BRN | 2822009 |
InChIKey | BHQCQFFYRZLCQQ-OELDTZBJSA-N |
LogP | 2.03-2.615 at 20℃ |
CAS DataBase Reference | 81-25-4(CAS DataBase Reference) |
NIST Chemistry Reference | Cholic acid(81-25-4) |
EPA Substance Registry System | Cholan-24-oic acid, 3,7,12-trihydroxy-, (3.alpha.,5.beta.,7.alpha.,12.alpha.)- (81-25-4) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H315-H319 | |||||||||
Precautionary statements | P305+P351+P338 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 24/25-36-26 | |||||||||
RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution | |||||||||
WGK Germany | 2 | |||||||||
RTECS | FZ9350000 | |||||||||
TSCA | Yes | |||||||||
HS Code | 29181990 | |||||||||
NFPA 704 |
|
Cholic acid price More Price(9)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | C1129 | Cholic acid from bovine and/or ovine, ≥98% | 81-25-4 | 25G | ₹3691.33 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | C1129 | Cholic acid from bovine and/or ovine, ≥98% | 81-25-4 | 100G | ₹7642.45 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | C1129 | Cholic acid from bovine and/or ovine, ≥98% | 81-25-4 | 500G | ₹30526.5 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | C1129 | Cholic acid from bovine and/or ovine, ≥98% | 81-25-4 | 1KG | ₹45768.1 | 2022-06-14 | Buy |
ottokemi | C 2195 | Cholic acid 98%+ | 81-25-4 | 25gm | ₹2205 | 2022-05-26 | Buy |
Cholic acid Chemical Properties,Uses,Production
Chemical Properties
white to light beige crystalline powder
Uses
Cholic Acid is an emulsifier that exists as colorless plates or a white crystalline powder which has a bitter taste with a sweetish aftertaste. it is slightly soluble in water. it functions as an emulsifying agent in egg white.
Definition
ChEBI: A bile acid that is 5beta-cholan-24-oic acid bearing three alpha-hydroxy substituents at position 3, 7 and 12.
General Description
This Certified Spiking Solution? is suitable as a starting material in preparation of linearity standards, calibrators, and controls for use in LC-MS/MS and GC/MS bile acid testing methods. Cholic acid is a primary bile acid that plays an important role in cholesterol homeostasis and intestinal absorption of dietary vitamins and lipids. Levels of cholic acid can serve as markers for inborn and acquired hepatobiliary disorders such as biliary atresia and familial intrahepatic cholestasis as well as inborn errors of bile acid synthesis and sclerosing cholangitis.
Purification Methods
This bile acid crystallises from H2O or wet Et2O (as hydrate) or EtOH (as alcoholate). Dry it under vacuum at 94o. When an alcoholic solution of cholic acid + I2 is added to aqueous KI, it forms a molecular compound (C24H40O5I)4 KI. H2O. The methyl ester is dimorphic with m 155o and 162o and [] D 20 +25o (EtOH). [Anderson et al. Biochem J 67 323 1957, 85 236 1962, Beilstein 10 III 2162, IV 2071.]
Cholic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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Otto Chemie Pvt Ltd | +91-2222070099 +91-2266382599 | Maharashtra, India | 429 | 58 | Inquiry |
PERFECT CHEMICAL | +91-9820465461 +91-9820465461 | Mumbai, India | 391 | 58 | Inquiry |
ADVENT CHEMBIO PRIVATE LIMITED | +91-9821524116 +91-9821524116 | Mumbai, India | 353 | 58 | Inquiry |
SynThink RESEARCH CHEMICALS | +91-8177860948 +91-8177860948 | Mumbai, India | 494 | 58 | Inquiry |
Scientific OEM | +91-22- 2343 7546 / 2341 3094 | New Delhi, India | 1996 | 38 | Inquiry |
ALPHA CHEMIKA | +91-22-22061123 +91-22-66382501 | Mumbai, India | 1681 | 43 | Inquiry |
CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4317 | 58 | Inquiry |
Supplier | Advantage |
---|---|
Otto Chemie Pvt Ltd | 58 |
PERFECT CHEMICAL | 58 |
ADVENT CHEMBIO PRIVATE LIMITED | 58 |
SynThink RESEARCH CHEMICALS | 58 |
Scientific OEM | 38 |
ALPHA CHEMIKA | 43 |
CHEMSWORTH | 30 |
TCI Chemicals (India) Pvt. Ltd. | 58 |
Otto Chemie Pvt. Ltd. | 58 |
Sisco Research Laboratories Pvt. Ltd. | 58 |
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