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Cholic acid

Cholic acid Structure
CAS No.
81-25-4
Chemical Name:
Cholic acid
Synonyms
CA;CHOLATE;cholan-24-oic acid;3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid;3A,7A,12A-TRIHYDROXY-5B-CHOLAN-24-OIC ACID;(R)-4-((3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-diMethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid;CHOLALIN;Cholicaci;Cholic acd;CHOLIC ACID
CBNumber:
CB9263222
Molecular Formula:
C24H40O5
Molecular Weight:
408.58
MOL File:
81-25-4.mol
MSDS File:
SDS
Modify Date:
2024/8/21 22:41:43
Request For Quotation

Cholic acid Properties

Melting point 200-201 °C (lit.)
Boiling point 449.08°C (rough estimate)
alpha 36 º (c=0.6, 95% EtOH)
Density 1.0310 (rough estimate)
refractive index 1.5800 (estimate)
Flash point 9℃
storage temp. 2-8°C
solubility methanol: 0.1 g/mL, clear
pka 4.98(at 20℃)
form Solid
color White to Brown
Water Solubility 0.28 g/L (15 ºC)
Merck 14,2203
BRN 2822009
InChIKey BHQCQFFYRZLCQQ-OELDTZBJSA-N
LogP 2.03-2.615 at 20℃
CAS DataBase Reference 81-25-4(CAS DataBase Reference)
NIST Chemistry Reference Cholic acid(81-25-4)
EPA Substance Registry System Cholan-24-oic acid, 3,7,12-trihydroxy-, (3.alpha.,5.beta.,7.alpha.,12.alpha.)- (81-25-4)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  24/25-36-26
RIDADR  UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany  2
RTECS  FZ9350000
TSCA  Yes
HS Code  29181990
NFPA 704
1
2 0

Cholic acid price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) C1129 Cholic acid from bovine and/or ovine, ≥98% 81-25-4 25G ₹3691.33 2022-06-14 Buy
Sigma-Aldrich(India) C1129 Cholic acid from bovine and/or ovine, ≥98% 81-25-4 100G ₹7642.45 2022-06-14 Buy
Sigma-Aldrich(India) C1129 Cholic acid from bovine and/or ovine, ≥98% 81-25-4 500G ₹30526.5 2022-06-14 Buy
Sigma-Aldrich(India) C1129 Cholic acid from bovine and/or ovine, ≥98% 81-25-4 1KG ₹45768.1 2022-06-14 Buy
ottokemi C 2195 Cholic acid 98%+ 81-25-4 25gm ₹2205 2022-05-26 Buy
Product number Packaging Price Buy
C1129 25G ₹3691.33 Buy
C1129 100G ₹7642.45 Buy
C1129 500G ₹30526.5 Buy
C1129 1KG ₹45768.1 Buy
C 2195 25gm ₹2205 Buy

Cholic acid Chemical Properties,Uses,Production

Chemical Properties

white to light beige crystalline powder

Uses

Cholic Acid is an emulsifier that exists as colorless plates or a white crystalline powder which has a bitter taste with a sweetish aftertaste. it is slightly soluble in water. it functions as an emulsifying agent in egg white.

Definition

ChEBI: A bile acid that is 5beta-cholan-24-oic acid bearing three alpha-hydroxy substituents at position 3, 7 and 12.

General Description

This Certified Spiking Solution? is suitable as a starting material in preparation of linearity standards, calibrators, and controls for use in LC-MS/MS and GC/MS bile acid testing methods. Cholic acid is a primary bile acid that plays an important role in cholesterol homeostasis and intestinal absorption of dietary vitamins and lipids. Levels of cholic acid can serve as markers for inborn and acquired hepatobiliary disorders such as biliary atresia and familial intrahepatic cholestasis as well as inborn errors of bile acid synthesis and sclerosing cholangitis.

Purification Methods

This bile acid crystallises from H2O or wet Et2O (as hydrate) or EtOH (as alcoholate). Dry it under vacuum at 94o. When an alcoholic solution of cholic acid + I2 is added to aqueous KI, it forms a molecular compound (C24H40O5I)4 KI. H2O. The methyl ester is dimorphic with m 155o and 162o and [] D 20 +25o (EtOH). [Anderson et al. Biochem J 67 323 1957, 85 236 1962, Beilstein 10 III 2162, IV 2071.]

Cholic acid Preparation Products And Raw materials

Raw materials

Ethanol Taurine HYOCHOLIC ACID Ethyl acetate Sulfuric acid

Preparation Products

Atificial Cow-bezoar Glycocholic acid GLYCOCHOLIC ACID SODIUM SALT 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholan-24-oic acid Dehydrocholic acid
Sodium taurocholate APOCHOLIC ACID (3a,5b,6a,12a)-3,6,12-trihydroxy-Cholan-24-oic acid
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Cholic acid Suppliers

Global( 588)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Otto Chemie Pvt Ltd +91-2222070099 +91-2266382599 Maharashtra, India 429 58 Inquiry
PERFECT CHEMICAL +91-9820465461 +91-9820465461 Mumbai, India 391 58 Inquiry
ADVENT CHEMBIO PRIVATE LIMITED +91-9821524116 +91-9821524116 Mumbai, India 353 58 Inquiry
SynThink RESEARCH CHEMICALS +91-8177860948 +91-8177860948 Mumbai, India 494 58 Inquiry
Scientific OEM +91-22- 2343 7546 / 2341 3094 New Delhi, India 1996 38 Inquiry
ALPHA CHEMIKA +91-22-22061123 +91-22-66382501 Mumbai, India 1681 43 Inquiry
CHEMSWORTH +91-261-2397244 New Delhi, India 6707 30 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
Otto Chemie Pvt. Ltd. +91 9820041841 Mumbai, India 5873 58 Inquiry
Sisco Research Laboratories Pvt. Ltd. +91-22-4268 5800 Mumbai, India 4317 58 Inquiry
Supplier Advantage
Otto Chemie Pvt Ltd 58
PERFECT CHEMICAL 58
ADVENT CHEMBIO PRIVATE LIMITED 58
SynThink RESEARCH CHEMICALS 58
Scientific OEM 38
ALPHA CHEMIKA 43
CHEMSWORTH 30
TCI Chemicals (India) Pvt. Ltd. 58
Otto Chemie Pvt. Ltd. 58
Sisco Research Laboratories Pvt. Ltd. 58

Cholic acid Spectrum

Cholic acid(81-25-4)1HNMRCholic acid(81-25-4)13CNMRCholic acid(81-25-4)IR1Cholic acid(81-25-4)IR2Cholic acid(81-25-4)Raman

81-25-4(Cholic acid)Related Search:

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Allo-UDCA (4R)-4-[(3S,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid Ascoric Acid (+)-NEOMENTHOL (2R,5S)-5-(5-Fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester
(2S)-2-[[[(1,1-Dimethylethyl)diphenylsilyl]oxy]methyl]-1,3-oxathiolan-5-ol 5-Acetate Emtricitabine Impurity 18 5-fluoro-1-(2-(hydroxymethyl)-1,3-dioxolan-4-yl)cytosine
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CHOLALIN CHOLAN-24-OIC ACID, 3,7,12-TRIHYDROXY-, (3,5,7,12)- CHOLIC ACID 3α,7α,12α-Trihydroxy-5α-cholanic acid, Cholic acd Cyclosphorine CHOLIC ACID FREE ACID Cholic Acid, High Purity CHOLIC ACID:CHOLAN-24-OICACID, 3,7,12-TRIHYDROXY-, (3,5,7,12)-, CholicAcidForBiochemistry Cholic acid, 98+% Bronchokod-13C3 S-(CarboxyMethyl)-L-cysteine-13C3 Cholic Acid (CA) Cholic acid SynonyMs 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholanic acid Cholic acid Vetec(TM) reagent grade, 98% (4R)-4-[(8R,9S,10S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid (4R)-4-[(8R,9S,10S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]valeric acid CHOLICACID(FROMOX,BOVINE) CHOLICACID(FROMPORCINE,PIG) (4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid 3,7,12-Trihydroxy-cholan-24-oic acid 5beta-Cholan-24-oic acid, 3alpha,7alpha,12alpha-trihydroxy- Cholan-24-oic acid, 3,7,12-trihydroxy-, (3alpha,5beta,7alpha,12alpha)- 3,7,12-TRIHYDROXYCHOLANIC ACID 3ALPHA, 7ALPHA, 12ALPHA-TRIHYDROXY-5BETA-CHOLANIC ACID 3ALPHA,7ALPHA,12ALPHA-TRIHYDROXY-5BETA-CHOLAN-24-IC ACID 3ALPHA,7ALPHA,12ALPHA-TRIHYDROXY-5BETA-CHOLAN-24-OIC ACID 7-ALPHA,8-ALPHA,12-ALPHA-TRIHYDROXY-5-BETA-CHOLAN-24-OIC ACID 5-BETA-CHOLANIC ACID-3-ALPHA, 7-ALPHA, 12-ALPHA-TRIOL CHOLALIC ACID CHOLIC ACID(P) Isoursocholic acid 17b-[1-Methyl-3-carboxypropyl]etiocholane-3a,7a,12a-triol 5b-Cholanic acid-3a,7a,12a-triol 5b-Cholic acid Cholan-24-oic acid, 3,7,12-trihydroxy-, (3a,5b,7a,12a)- trihydroxycholanic acid 3α,7α,12α-Trihydroxy-5β-cholanic acid, Cholanic acid Cholicacid，Cholan-24-oic acid 17β-(1-methyl-3-carboxy-propyl)etiocholane-3α，7α，12α-triol Cholic acid,97% Cholic acid,3α,7α,12α-Trihydroxy-5β-cholanic acid, Cholanic acid Cholic Acid (AS) (3α,5β,7α12α)-3,7,12-Trihydroxy-cholan-24-oic Acid (2R)-2-AMino-3-[(carboxyMethyl)thio]propionic Acid-13C3 (L)-2-AMino-3-(carboxyMethylthio)propionic Acid-13C3 (R)-S-(CarboxyMethyl)cysteine-13C3 3-[(CarboxyMethyl)thio]-L-alanine-13C3 AHR 3053-13C3 Cholic Acid (2 g) Cholic  Cholic acid, 97% 100GR Cholic acid, 97% 25GR cholic acid powder Ursodeoxycholic Acid EP Impurity B(Cholic Acid) Cholan-24-oicacid, 3,7,12-trihydroxy Ursodeoxycholic Acid Impurity 2（Ursodeoxycholic Acid EP Impurity B）