MY-5445

MY-5445 Structure
CAS No.
78351-75-4
Chemical Name:
MY-5445
Synonyms
MY-5445;MY 5445;MY5445;1-(3-CHLOROANILINO)-4-PHENYLPHTHALAZINE;1-(3-Chloroanilino)-4-phenylphthalazine >1-(3-CHLOROPHENYLAMINO)-4-PHENYLPHTHALAZINE;N-(3-chlorophenyl)-4-phenylphthalazin-1-amine;N-(3-Chlorophenyl)-4-phenyl-1-phthalazinamine;1-Phthalazinamine, N-(3-chlorophenyl)-4-phenyl-;aggregation,platelet,Inhibitor,anticancer,inhibit,MY5445,neuropathic,MY 5445,Phosphodiesterase (PDE),neuropathic pain,allodynia,MY-5445
CBNumber:
CB9739543
Molecular Formula:
C20H14ClN3
Molecular Weight:
331.8
MOL File:
78351-75-4.mol
MSDS File:
SDS
Modify Date:
2023/7/12 16:43:44

MY-5445 Properties

Boiling point 539.7±50.0 °C(Predicted)
Density 1.310±0.06 g/cm3(Predicted)
storage temp. Store at RT
solubility DMF: 2 mg/ml; DMSO: 2 mg/ml; DMSO:PBS(pH 7.2) (1:2): 0.3 mg/ml
pka 4.91±0.30(Predicted)
form Yellow solid.
color White to Light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H319-H315-H335
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
HS Code  2933.99.8290
NFPA 704
0
2 0

MY-5445 price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemicals (India) C2884 1-(3-Chloroanilino)-4-phenylphthalazine min. 98.0 % 78351-75-4 20MG ₹5000 2022-05-26 Buy
TCI Chemicals (India) C2884 1-(3-Chloroanilino)-4-phenylphthalazine min. 98.0 % 78351-75-4 100MG ₹14800 2022-05-26 Buy
Product number Packaging Price Buy
C2884 20MG ₹5000 Buy
C2884 100MG ₹14800 Buy

MY-5445 Chemical Properties,Uses,Production

Description

MY-5445 is a selective inhibitor of the cyclic GMP (cGMP) phosphodiesterase, PDE5, with a Ki value of 1.3 μM. It inhibits calcium- and cAMP-selective PDEs with Ki values of >1,000 and 915 μM, respectively. MY-5445 has been shown to relax intact strips of rat aorta with an EC50 value of 4 μM.

Uses

MY-5445 is a selective cGMP phosphodiesterase inhibitor. Potent PDE5 inhibitor.

Biological Activity

Specific inhibitor of cyclic GMP phosphodiesterase, selective for PDE5 (IC 50 = 0.5 μ M).

MY-5445 Preparation Products And Raw materials

Raw materials

Preparation Products

MY-5445 Suppliers

Global( 89)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49392 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
LEAP CHEM CO., LTD. +86-852-30606658 China 24738 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
Morning Student Science and Technology (Guangzhou) Co., Ltd. 020-36048871 13760856740 CHINA 6618 58 Inquiry
Beijing Huaxia Ocean Technology Co., Ltd. 010-62898668 15311620006 CHINA 6122 58 Inquiry
MY-5445 1-(3-CHLOROPHENYLAMINO)-4-PHENYLPHTHALAZINE 1-(3-CHLOROANILINO)-4-PHENYLPHTHALAZINE N-(3-Chlorophenyl)-4-phenyl-1-phthalazinamine N-(3-chlorophenyl)-4-phenylphthalazin-1-amine MY 5445;MY5445 1-(3-Chloroanilino)-4-phenylphthalazine > aggregation,platelet,Inhibitor,anticancer,inhibit,MY5445,neuropathic,MY 5445,Phosphodiesterase (PDE),neuropathic pain,allodynia,MY-5445 1-Phthalazinamine, N-(3-chlorophenyl)-4-phenyl- 78351-75-4 C20H14ClN3 Cyclic Nucleotide related