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H-89 DIHYDROCHLORIDE HYDRATE

H-89 DIHYDROCHLORIDE HYDRATE Structure
CAS No.
130964-39-5
Chemical Name:
H-89 DIHYDROCHLORIDE HYDRATE
Synonyms
H 89 2HCl;5-Isoquinolinesulfonamide;H-89 DIHYDROCHLORIDE HYDRATE;H-89 hydrate dihydrochloride;H-89 DIHYDROCHLORIDE HYDRATE USP/EP/BP;Protein kinase inhibitor H-89 dihydrochloride;H-89 Dihydrochloride Hydrate,N-[2-(P-Bromocinnamylamino)Et;H-89 dihydrochloride(Protein kinase inhibitor H-89 dihydrochloride);PROTEIN KINASE INHIBITOR H-89 DIHYDROCHLORIDE; H89 DIHYDROCHLORIDE;H 89;(E)-N-(2-(4-bromocinnamylamino)ethyl)isoquinoline-5-sulfonamide dihydrochloride
CBNumber:
CB9972711
Molecular Formula:
C20H20BrN3O2S.2ClH.H2O
Molecular Weight:
537.304
MOL File:
130964-39-5.mol
MSDS File:
SDS
Modify Date:
2023/6/30 15:45:59

H-89 DIHYDROCHLORIDE HYDRATE Properties

Melting point 195-200°C
storage temp. Inert atmosphere,2-8°C
solubility H2O: ≥10mg/mL
form powder
color off-white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P271-P280
Safety Statements  22-24/25
WGK Germany  3
HS Code  2935909099

H-89 DIHYDROCHLORIDE HYDRATE price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) B1427 H-89 dihydrochloride hydrate ≥98% (HPLC), powder 130964-39-5 5MG ₹20654.1 2022-06-14 Buy
Product number Packaging Price Buy
B1427 5MG ₹20654.1 Buy

H-89 DIHYDROCHLORIDE HYDRATE Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

H-89 dihydrochloride hydrate has been used in the inhibition of protein kinase A in Leydig cells, primary calvarial osteoblasts (pOBs), rat granulosa cell line (LH-15 cells) and human umbilical vein endothelial cells (HUVECs).

Biochem/physiol Actions

H-89 dihydrochloride hydrate is a selective inhibitor of protein kinase A (PKA). It also inhibits potassium (K+) current in rat myocytes. It mediates Na+ transport by interacting with α subunits of epithelial Na+ channel (ENaC).

H-89 DIHYDROCHLORIDE HYDRATE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 122)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Hangzhou FandaChem Co.,Ltd. 008657128800458; +8615858145714 China 9240 55 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32835 60 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 23430 58 Inquiry
Finetech Industry Limited +86-27-87465837 +8618971612321 China 9640 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Nanjing Doge Biomedical Technology Co., Ltd +86-25-58227606 +86-15305155328 China 4128 58 Inquiry

H-89 DIHYDROCHLORIDE HYDRATE Spectrum

H-89 DIHYDROCHLORIDE HYDRATE H-89 hydrate dihydrochloride H-89 dihydrochloride hydrate,N-[2-(p-Bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide dihydrochloride 5-IsoquinolinesulfonaMide, N-[2-[[3-(4-broMophenyl)-2-propenyl]aMino]ethyl]-, dihydrochloride N-[2-[[3-(4-BroMophenyl)-2-propen-1-yl]aMino]ethyl]-5-isoquinolinesulfonaMide Hydrochloride H 89 2HCl Protein kinase inhibitor H-89 dihydrochloride (E)-N-(2-(4-bromocinnamylamino)ethyl)isoquinoline-5-sulfonamide dihydrochloride (E)-N-(2-((3-(4-bromophenyl)allyl)amino)ethyl)isoquinoline-5-sulfonamide dihydrochloride H-89 Dihydrochloride Hydrate,N-[2-(P-Bromocinnamylamino)Et N-[2-[[3-(4-Bromophenyl)-2-Propen-1-Yl]Amino]Ethyl]-5-Isoquinolinesulfonamide Hydrochloride (1:2) PROTEIN KINASE INHIBITOR H-89 DIHYDROCHLORIDE; H89 DIHYDROCHLORIDE;H 89 H-89 dihydrochloride(Protein kinase inhibitor H-89 dihydrochloride) PROTEIN KINASE INHIBITOR H-89 DIHYDROCHLORIDE;H89 DIHYDROCHLORIDE;H 89 DIHYDROCHLORIDE;H 89;H89 5-Isoquinolinesulfonamide H-89 DIHYDROCHLORIDE HYDRATE USP/EP/BP Protein kinase inhibitor H-89 dihydrochloride|||H 89 2HCl|||5-Isoquinolinesulfonamide 130964-39-5 Inhibitors Akt mTOR PI3K PI3K/Akt/mTOR Protein Kinase Inhibitors and Activators