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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Proteases >Proteasome inhibitors >(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid

(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid

(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid Structure
  • ₹0
  • Product name: (R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid
  • CAS: 1072833-77-2
  • MF: C14H19BCl2N2O4
  • MW: 361.03
  • EINECS:810-246-8
  • MDL Number:MFCD18251438
  • Synonyms:(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid;B-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]boronic acid;ixazomib(MLN2238);B-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]boronic acid Ixazomib (MLN2238);MLN2238(iaxzomib);MLN2238(Ixazomib);MLN2238;MLN 2238;MLN-2238;IXAZOMIB;MLN 2238;MLN-2238
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :>142°C (subl.)
Density :1.306
storage temp. :-20°C Freezer
solubility :DMSO (Sparingly), Methanol (Slightly)
pka :9.67±0.43(Predicted)
form :Solid
color :White to Pale Yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
H362 May cause harm to breast-fed children Reproductive toxicity, effects on or via lactation Additional category P201, P260, P263, P264, P270,P308+P313
Precautionary statements:
P201 Obtain special instructions before use.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P263 Avoid contact during pregnancy/while nursing.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Ixazomib is a proteasome inhibitor that acts by preventing cell growth in solid tumours. It is an anticancer agent that is used to treat patients with multiple myeloma and is potentially neurotoxic.