2-Cyano-3-hydroxy-N-(4'-trifluoromethylphenyl)-crotone amide
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- ₹56787.95
- Product name: 2-Cyano-3-hydroxy-N-(4'-trifluoromethylphenyl)-crotone amide
- CAS: 108605-62-5
- MF: C12H9F3N2O2
- MW: 270.21
- EINECS:1308068-626-2
- MDL Number:MFCD00910058
- Synonyms:N-(4-Trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide, 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-beuteamide, LEF-M;(2Z)-2-[hydroxy-[[4-(trifluoromethyl)phenyl]amino]methylidene]-3-oxo-butanenitrile;2-Cyano-3OH-N-(4-trifluoromethylphenyl) crotonamide-d4;IMp. A (EP) as Hydrochloride: 4-(TrifluoroMethyl)aniline Hydrochloride;TeriflunoMide, A77 1726;2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide;2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide;2-Cyano-3-hydroxy-N-(4'-trifluoromethylphenyl)-crotone amide
1 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 50MG
- ManufacturerSigma-Aldrich(India)
- Product numberPHR2878
- Product descriptionLeflunomide Related Compound B pharmaceutical secondary standard, certified reference material
- Packaging50MG
- Price₹56787.95
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | PHR2878 | Leflunomide Related Compound B pharmaceutical secondary standard, certified reference material | 50MG | ₹56787.95 | 2022-06-14 | Buy |
Properties
Melting point :229-232°C
Boiling point :410.8±45.0 °C(Predicted)
Density :1.424±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :Soluble in DMSO (up to 30 mg/ml), or in Ethanol (up to 5 mg/ml with warming).
form :Solid
pka :5.20±0.50(Predicted)
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Boiling point :410.8±45.0 °C(Predicted)
Density :1.424±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :Soluble in DMSO (up to 30 mg/ml), or in Ethanol (up to 5 mg/ml with warming).
form :Solid
pka :5.20±0.50(Predicted)
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
Teriflunomide (Aubagio®), also known as A77 1726, is an immunosupressant marketed by Sanofi for the teatment of multiple sclerosis (MS). Teriflunomide is the active metabolite of leflunomide, used for treatment of patients diagnosed with rheumatoid arthritis, and therefore simultaneously can be used as a treatment for rheumatoid arthritis.Teriflunomide acts as an inhibitor of the mitochondrial enzyme dihydrorotate dehydrogenase, inhibiting pyrimidine formation, and resulting in reduced B and T cell proliferation.Related product price
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