N-(2-[P-BROMOCINNAMYLAMINO]ETHYL)-5-ISOQUINOLINESULFONAMIDE HYDROCHLORIDE
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- Product name: N-(2-[P-BROMOCINNAMYLAMINO]ETHYL)-5-ISOQUINOLINESULFONAMIDE HYDROCHLORIDE
- CAS: 127243-85-0
- MF: C20H20BrN3O2S
- MW: 446.36
- EINECS:
- MDL Number:MFCD00214119
- Synonyms:H-89;H-89 DIHYDROCHLORIDE;H-89 HYDROCHLORIDE;N-[2-(P-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE SULFONAMIDE;N-[2-(P-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINESULFONAMIDE 2HCL;N-[2-(P-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE SULFONAMIDE, DIHYDROCHLORIDE;N-(2-[P-BROMOCINNAMYLAMINO]ETHYL)-5-ISOQUINOLINESULFONAMIDE HYDROCHLORIDE;N-[2-[P-BROMOCINNAMYLAMINO]-ETHYL]-5-ISOQUINOLINESULFONMIDE
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
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Properties
Melting point :195-200°C
Boiling point :639.7±65.0 °C(Predicted)
Density :1.436
storage temp. :2-8°C
solubility :H2O: ≥10 mg/mL
form :powder
pka :10.43±0.50(Predicted)
color :off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
CAS DataBase Reference :127243-85-0(CAS DataBase Reference)
Boiling point :639.7±65.0 °C(Predicted)
Density :1.436
storage temp. :2-8°C
solubility :H2O: ≥10 mg/mL
form :powder
pka :10.43±0.50(Predicted)
color :off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
CAS DataBase Reference :127243-85-0(CAS DataBase Reference)
Safety Information
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Description
H-89, Dihydrochloride is a cell-permeable, non-selective, reversible, ATP-competitive, potent inhibitor of PKA (cyclic AMP-dependent protein kinase). PKA regulates glycogen, sugar and lipid metabolism and plays an important role in the cell cycle. H-89, once thought to be a selective PKA inhibitor, has been shown to also inhibit CaM kinase II, casein kinase I, Rsk-2 (MAPKAP-K1b), MSK1, MYLK (myosin light chain kinase), Akt1 (PKB α), PKC μ, Rock-2 (ROCK-II) and p70 S6 kinase α.More related product prices
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