25-hydroxycholesterol
- ₹10900.78 - ₹34434.33
- Product name: 25-hydroxycholesterol
- CAS: 2140-46-7
- MF: C27H46O2
- MW: 402.65
- EINECS:
- MDL Number:MFCD00057815
- Synonyms:25-HYDROXYCHOLESTEROL;3BETA,25-DIHYDROXY-5-CHOLESTENE;5-CHOLESTEN-3-BETA, 25-DIOL;5-CHOLESTENE-3BETA,25-DIOL;25-Hydroxycholesterol (not deuterated);Cholest-5-ene-3,25-diol, (3.beta.)-;5-cholestene-3β,25-diol;(3S,8S,9S,10R,13R,14S,17R)-17-[(2R)-6-hydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
3 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 10MG
- 25MG
- 100MG
- ManufacturerSigma-Aldrich(India)
- Product numberH1015
- Product description25-Hydroxycholesterol ≥98%
- Packaging10MG
- Price₹10900.78
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberH1015
- Product description25-Hydroxycholesterol ≥98%
- Packaging25MG
- Price₹17233.4
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberH1015
- Product description25-Hydroxycholesterol ≥98%
- Packaging100MG
- Price₹34434.33
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | H1015 | 25-Hydroxycholesterol ≥98% | 10MG | ₹10900.78 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | H1015 | 25-Hydroxycholesterol ≥98% | 25MG | ₹17233.4 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | H1015 | 25-Hydroxycholesterol ≥98% | 100MG | ₹34434.33 | 2022-06-14 | Buy |
Properties
Melting point :177-179 °C
Boiling point :513.1±23.0 °C(Predicted)
Density :1.03±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :chloroform: 50 mg/mL, clear, colorless to slightly yellow
pka :15.03±0.70(Predicted)
form :solid
color :White or pale yellow
Merck :13,4846
BRN :3161259
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChIKey :INBGSXNNRGWLJU-ZHHJOTBYSA-N
SMILES :[C@@]12([H])CC[C@H]([C@H](C)CCCC(O)(C)C)[C@@]1(C)CC[C@]1([H])[C@@]3(C)CC[C@H](O)CC3=CC[C@@]21[H] |&1:0,4,5,14,18,20,24,30,r|
Boiling point :513.1±23.0 °C(Predicted)
Density :1.03±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :chloroform: 50 mg/mL, clear, colorless to slightly yellow
pka :15.03±0.70(Predicted)
form :solid
color :White or pale yellow
Merck :13,4846
BRN :3161259
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChIKey :INBGSXNNRGWLJU-ZHHJOTBYSA-N
SMILES :[C@@]12([H])CC[C@H]([C@H](C)CCCC(O)(C)C)[C@@]1(C)CC[C@]1([H])[C@@]3(C)CC[C@H](O)CC3=CC[C@@]21[H] |&1:0,4,5,14,18,20,24,30,r|
Safety Information
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Signal word: | Warning | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
25-hydroxy Cholesterol is a side-chain substituted oxysterol derived from dietary cholesterol that inhibits the cleavage of sterol regulatory element binding proteins (SREBPs) to suppress endogenous cholesterol synthesis in various cell types. It has been implicated in a variety of metabolic events including cholesterol homeostasis and atherosclerosis as well as antitumor activities as it has been shown to induce apoptosis through down-regulation of Bcl-2 expression and activation of caspases. Immunomodulating capabilities have also been observed as the oxysterol can act as a LXR-RXR ligand coupling cholesterol synthesis to T cell proliferation, can reduce (EC50 ~ 65 nM) IgA production by B cells in response to IL-2, and can suppress differentiation of monocytes into macrophages.More related product prices
Fluvastatin sodium salt FILIPIN III ML335 Lovastatin 7BETA-HYDROXYCHOLESTEROL 7-KETOCHOLESTEROL 5-CHOLESTEN-3-BETA, 7-ALPHA-DIOLRelated product price
- Fluvastatin sodium salt
₹9700-39143.2 - FILIPIN III
₹17915.38-59818.95 - Lovastatin
₹8042.98-22440.23
Suppliers and manufacturers
Varanous Labs Pvt Ltd
Pharma Affiliates
CLEARSYNTH LABS LTD.
A.J Chemicals
Pharmaffiliates Analytics and Synthetics P. Ltd