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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Epigenetics >Histone Demethylase inhibitors >5-Carboxy-8-hydroxyquinoline

5-Carboxy-8-hydroxyquinoline

5-Carboxy-8-hydroxyquinoline Structure
  • ₹12578.65 - ₹50780.08
  • Product name: 5-Carboxy-8-hydroxyquinoline
  • CAS: 5852-78-8
  • MF: C10H7NO3
  • MW: 189.17
  • EINECS:
  • MDL Number:MFCD18417145
  • Synonyms:5-Carboxy-8-hydroxyquinoline;8-hydroxy-5-Quinolinecarboxylic acid;IOX 1, >=98%;JMJD2 Inhibitor, 5-carboxy-8HQ ;8-Hydroxyquinoline-5-carboxylic acid 95%;JMJD2 Inhibitor, 5-carboxy-8HQ - CAS 5852-78-8 - Calbiochem;CS-1524;IOX-1;IOX 1
3 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0067
  • Product descriptionIOX1 ≥97% (HPLC)
  • Packaging5MG
  • Price₹12578.65
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number420201
  • Product descriptionJMJD2 Inhibitor, 5-carboxy-8HQ - CAS 5852-78-8 - Calbiochem The JMJD2 Inhibitor, 5-carboxy-8HQ, also referenced under CAS 5852-78-8, controls the biological activity of JMJD2. This small molecule/inhibitor is p
  • Packaging5MG
  • Price₹19050
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0067
  • Product descriptionIOX1 ≥97% (HPLC)
  • Packaging25MG
  • Price₹50780.08
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML0067 IOX1 ≥97% (HPLC) 5MG ₹12578.65 2022-06-14 Buy
Sigma-Aldrich(India) 420201 JMJD2 Inhibitor, 5-carboxy-8HQ - CAS 5852-78-8 - Calbiochem The JMJD2 Inhibitor, 5-carboxy-8HQ, also referenced under CAS 5852-78-8, controls the biological activity of JMJD2. This small molecule/inhibitor is p 5MG ₹19050 2022-06-14 Buy
Sigma-Aldrich(India) SML0067 IOX1 ≥97% (HPLC) 25MG ₹50780.08 2022-06-14 Buy

Properties

Melting point :301 °C (decomp)
Boiling point :464.5±30.0 °C(Predicted)
Density :1.480±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear
pka :1.82±0.10(Predicted)
form :powder
color :white to brown
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
InChIKey :JGRPKOGHYBAVMW-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

IOX 1 (5852-78-8) inhibits the JMJD family of 2-oxoglutarate-dependent histone demethylases. IC50 = 0.12, 0.07, 0.2, 0.3, 0.6, and 1 μM for JMJD3, JMJD1A, JMJD2A, JMJD2E, JMJD2C and UTX respectively.1?A broad spectrum 2-oxoglutarate oxygenase inhibitor, IOX 1 may be used to study hypoxic signaling.1?Cell permeable

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