5-(6-Quinoxalinylmethylene)-2,4-thiazolidinedione
- ₹14624.58 - ₹52457.95
- Product name: 5-(6-Quinoxalinylmethylene)-2,4-thiazolidinedione
- CAS: 648450-29-7
- MF: C12H7N3O2S
- MW: 257.27
- EINECS:
- MDL Number:MFCD11100415
- Synonyms:5-(6-Quinoxalinylmethylene)-2,4-thiazolidinedione;AS605240;5-(6-Quinoxalinylmethylene)-2,4-thiazolidine-2,4-dione;PI 3-Kinase Inhibitor (AS605240) B-0301;AS-605240, >=98%;(E)-5-(quinoxalin-6-ylMethylene)thiazolidine-2,4-dione;2,4-Thiazolidinedione, 5-(6-quinoxalinylMethylene)-;AS-605240(AS 605240)
3 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberA0233
- Product descriptionAS605240 ≥98% (HPLC)
- Packaging25MG
- Price₹52457.95
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number528106
- Product descriptionPI 3-Kγ Inhibitor - CAS 648450-29-7 - Calbiochem The PI 3-Kγ Inhibitor, also referenced under CAS 648450-29-7, controls the biological activity of PI 3-Kγ. This small molecule/inhibitor is primarily
- Packaging5MG
- Price₹20250
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA0233
- Product descriptionAS605240 ≥98% (HPLC)
- Packaging5MG
- Price₹14624.58
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | A0233 | AS605240 ≥98% (HPLC) | 25MG | ₹52457.95 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 528106 | PI 3-Kγ Inhibitor - CAS 648450-29-7 - Calbiochem The PI 3-Kγ Inhibitor, also referenced under CAS 648450-29-7, controls the biological activity of PI 3-Kγ. This small molecule/inhibitor is primarily | 5MG | ₹20250 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | A0233 | AS605240 ≥98% (HPLC) | 5MG | ₹14624.58 | 2022-06-14 | Buy |
Properties
Density :1.553±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble1mg/mL, clear (warmed)
pka :6.02±0.20(Predicted)
form :powder
color :, faint red to orange to dark brown
storage temp. :2-8°C
solubility :DMSO: soluble1mg/mL, clear (warmed)
pka :6.02±0.20(Predicted)
form :powder
color :, faint red to orange to dark brown
Safety Information
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Description
PI 3-Kγ Inhibitor is a cell-permeable thiazolidinedione compound that acts as a potent, selective, and ATP-competitive inhibitor of PI 3-kinase γ (PI 3-Kγ) (Ki = 7.8 nM; IC50 = 8 nM, 60 nM, 270 nM, 300 nM for p110-γ, α, β and δ-isoforms, respectively). PI 3-Kγ Inhibitor does not affect the activity of a wide panel of kinases, receptors, enzymes, and ion channels even at concentrations as high as 1 μM. It selectively blocks MCP-1-, but not CSF-1-, dependent Akt phosphorylation and chemotaxis in primary Pik3cg+/+ murine monocytes and in a human monocytic cell line THP-1 (IC50 = 181 nM). PI 3-Kγ Inhibitor has also been shown to exhibit efficacy in reducing neutrophil chemotaxis in murine peritonitis and arthritis models.More related product prices
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