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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Cell Cycle >Aurora Kinase Inhibitors >1H-Pyrazole-3-acetamide, 5-[[7-[3-[ethyl(2-hydroxyethyl)amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)-

1H-Pyrazole-3-acetamide, 5-[[7-[3-[ethyl(2-hydroxyethyl)amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)-

1H-Pyrazole-3-acetamide, 5-[[7-[3-[ethyl(2-hydroxyethyl)amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)- Structure
  • ₹11677.2 - ₹47208.3
  • Product name: 1H-Pyrazole-3-acetamide, 5-[[7-[3-[ethyl(2-hydroxyethyl)amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)-
  • CAS: 722544-51-6
  • MF: C26H30FN7O3
  • MW: 507.56
  • EINECS:
  • MDL Number:MFCD10687152
  • Synonyms:INH 34;2-(3-(7-(3-(Ethyl(2-hydroxyethyl)amino)propoxy)quinazolin-4-ylamino)-1H-pyrazol-5-yl)-N-(3-fluorophenyl)acetamide;5-[[7-[3-[Ethyl(2-hydroxyethyl)amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)-1H-pyrazole-3-acetamide;AZD1152-HQPA(Barasertib);2-[5-(7-{3-[Ethyl-(2-hydroxy-ethyl)-aMino]-propoxy}-quinazolin-4-ylaMino)-2H-pyr;1H-Pyrazole-3-acetamide, 5-[[7-[3-[ethyl(2-hydroxyethyl)amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)-;2-[5-(7-{3-[ETHYL-(2-HYDROXY-ETHYL)-AMINO]-PROPOXY}-QUINAZOLIN-4-YLAMINO)-2H-PYRAZOL-3-YL]-N-(3-FLUORO-PHENYL)-ACETAMIDE;AZD1152 HPQA
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0268
  • Product descriptionAZD1152-HQPA ≥98% (HPLC)
  • Packaging50MG
  • Price₹47208.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0268
  • Product descriptionAZD1152-HQPA ≥98% (HPLC)
  • Packaging10MG
  • Price₹11677.2
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML0268 AZD1152-HQPA ≥98% (HPLC) 50MG ₹47208.3 2022-06-14 Buy
Sigma-Aldrich(India) SML0268 AZD1152-HQPA ≥98% (HPLC) 10MG ₹11677.2 2022-06-14 Buy

Properties

Boiling point :796.7±60.0 °C(Predicted)
Density :1.359±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >15mg/mL
pka :13.07±0.10(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
InChIKey :QYZOGCMHVIGURT-UHFFFAOYSA-N
CAS DataBase Reference :722544-51-6

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

2-[5-(7-{3-[Ethyl-(2-hydroxy-ethyl)-amino]-propoxy}-quinazolin-4-ylamino)-2H-pyrazol-3-yl]-N-(3-fluoro-phenyl)-acetamide is a highly selective ARK-2 inhibitor with IC50 of 0.37 nM.

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