7-CHLORO-5-(2-CHLOROPHENYL)-1,5-DIHYDRO-4,1-BENZOTHIAZEPIN-2(3H)-ONE
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- ₹15674.6 - ₹63033.98
- Product name: 7-CHLORO-5-(2-CHLOROPHENYL)-1,5-DIHYDRO-4,1-BENZOTHIAZEPIN-2(3H)-ONE
- CAS: 75450-34-9
- MF: C15H11Cl2NOS
- MW: 324.22
- EINECS:
- MDL Number:MFCD09055422
- Synonyms:7-CHLORO-5-(2-CHLOROPHENYL)-1,5-DIHYDRO-4,1-BENZOTHIAZEPIN-2(3H)-ONE;CGP 37157;7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepine-2(3H)-one;4,1-Benzothiazepin-2(3H)-one, 7-chloro-5-(2-chlorophenyl)-1,5-dihydro-;7-chloro-5-(2-chlorophenyl)benzo[e][1,4]thiazepin-2(1H,3H,5H)-one;CGP-37157 - CAS 75450-34-9 - Calbiochem;1-benzothiazepine-2(3H)-one;7-Chloro-5-(2-chlorophenyl)-1
3 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberC8874
- Product descriptionCGP-37157 ≥98% (HPLC), powder
- Packaging25MG
- Price₹63033.98
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number220005
- Product descriptionCGP-37157 - CAS 75450-34-9 - Calbiochem A cell-permeable benzothiazepine derivative of clonazepam that acts as a specific and potent inhibitor of the mitochondrial Na+/Ca2+ exchanger (IC?? =
- Packaging5MG
- Price₹23839.99
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberC8874
- Product descriptionCGP-37157 ≥98% (HPLC), powder
- Packaging5MG
- Price₹15674.6
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | C8874 | CGP-37157 ≥98% (HPLC), powder | 25MG | ₹63033.98 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 220005 | CGP-37157 - CAS 75450-34-9 - Calbiochem A cell-permeable benzothiazepine derivative of clonazepam that acts as a specific and potent inhibitor of the mitochondrial Na+/Ca2+ exchanger (IC?? = | 5MG | ₹23839.99 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C8874 | CGP-37157 ≥98% (HPLC), powder | 5MG | ₹15674.6 | 2022-06-14 | Buy |
Properties
Boiling point :479.8±45.0 °C(Predicted)
Density :1.384±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥20mg/mL
pka :12.20±0.40(Predicted)
form :White solid
color :white
Stability :Stable for 2 years from date of purchase as supplied. Solution in DMSO may be stored at -20°C for up to 3 months.
Density :1.384±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥20mg/mL
pka :12.20±0.40(Predicted)
form :White solid
color :white
Stability :Stable for 2 years from date of purchase as supplied. Solution in DMSO may be stored at -20°C for up to 3 months.
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
CGP 37157 is a benzothiazepine that acts as a selective inhibitor of the mitochondrial sodium-calcium exchanger (IC50 = 0.36 μM in isolated mitochondria). It does not affect channels, exchangers, or ATPases on the cardiac sarcolemma or ATPases on sarcoplasmic reticulum. CGP 37157 is commonly used to study the role of mitochondrial-derived calcium in cytoplasmic calcium homeostasis. CGP 37157 inhibits sodium-dependent calcium efflux via the mitochondrial exchanger NCLX in a variety of cell types (IC50 = 5 μM).More related product prices
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