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Amsacrine hydrochloride

Amsacrine hydrochloride Structure
  • ₹7500 - ₹104190.63
  • Product name: Amsacrine hydrochloride
  • CAS: 54301-15-4
  • MF: C21H20ClN3O3S
  • MW: 429.92
  • EINECS:637-255-8
  • MDL Number:MFCD07799963
  • Synonyms:m-AMSA, 4-(9-Acridinylamino)-N-(methanesulfonyl)-m-anisidine hydrochloride;Methanesulfone-m-anisidine-4'-[(9-acridinyl)amino] hydrochloride;Methanesulfon-m-anisidide 4'-(9-acridinylamino)-;Methansulfon-m-aniside, 4'-(9-acridinylamino)-, monohydrochloride;4-[9-ACRIDINYLAMINO]-N-[METHANE-SULFONYL]-M-ANISIDINE HYDROCHLORIDE;M-AMSA HYDROCHLORIDE;M-AMSA, HCL;Methanesulfonamide, N-4-(9-acridinylamino)-3-methoxyphenyl-, monohydrochloride
4 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 20MG
  • 50MG
  • 100MG
  • ManufacturerTCI Chemicals (India)
  • Product numberA2777
  • Product descriptionAmsacrine Hydrochloride
  • Packaging20MG
  • Price₹7500
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberA2777
  • Product descriptionAmsacrine Hydrochloride
  • Packaging100MG
  • Price₹15000
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA9809
  • Product descriptionAmsacrine hydrochloride ≥98% (TLC), powder
  • Packaging10MG
  • Price₹26640.33
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA9809
  • Product descriptionAmsacrine hydrochloride ≥98% (TLC), powder
  • Packaging50MG
  • Price₹104190.63
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) A2777 Amsacrine Hydrochloride 20MG ₹7500 2022-05-26 Buy
TCI Chemicals (India) A2777 Amsacrine Hydrochloride 100MG ₹15000 2022-05-26 Buy
Sigma-Aldrich(India) A9809 Amsacrine hydrochloride ≥98% (TLC), powder 10MG ₹26640.33 2022-06-14 Buy
Sigma-Aldrich(India) A9809 Amsacrine hydrochloride ≥98% (TLC), powder 50MG ₹104190.63 2022-06-14 Buy

Properties

Melting point :197-199 °C(lit.)
storage temp. :Refrigerator
solubility :DMSO: 10 mg/mL with heat and sonication
form :powder
color :red to brown

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352 IF ON SKIN: wash with plenty of soap and water.

Description

Amsacrine hydrochloride has been used:
  • as a topoisomerase poison in bacteriophage T4 topoisomerase assay
  • as a topoisomerase inhibitor in Drosophila cell line, Kc167
  • as an antileukemia drug to test its effect on p53 transcriptional activity in tumor xenografts
  • as a topoisomerase II poison in dose-response assays in C elegans


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