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BMS-986020

BMS-986020 Structure
  • ₹0
  • Product name: BMS-986020
  • CAS: 1257213-50-5
  • MF: C29H26N2O5
  • MW: 482.53
  • EINECS:
  • MDL Number:MFCD30489743
  • Synonyms:BMS-986020;CS-2492;(R)-1-(4'-(3-methyl-4-(((1-phenylethoxy)carbonyl)amino)isoxazol-5-yl)-[1,1'-biphenyl]-4-yl)cyclopropane-1-carboxylic acid;BMS-986020;BMS 986020;BMS986020;1-{4'-[3-methyl-4-((R)-1-phenyl-ethoxycarbonylamino)-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid;AM152;Cyclopropanecarboxylic acid, 1-[4'-[3-methyl-4-[[[(1R)-1-phenylethoxy]carbonyl]amino]-5-isoxazolyl][1,1'-biphenyl]-4-yl]-;inhibit,idiopathic,AM-152,LPL Receptor,Lysophospholipid Receptor,AM 152,IPF,BMS-986020,fibrosis,pulmonary,BMS 986020,autoradiography,Inhibitor,ARG
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :174-180°C
Boiling point :664.8±55.0 °C(Predicted)
Density :1.309±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Methanol (Slightly, Sonicated)
form :Solid
pka :4.19±0.20(Predicted)
color :White to Off-White

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
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Description

BMS 986020 is a potent G protein-coupled lysophosphatidic acid receptor 1 (LPA1) antagonist with an IC50 value less than 300 nM for human LPA1 expressing CHO cells. Formulations containing BMS 986020 are being investigated in clinical trials for efficacy in idiopathic pulmonary fibrosis.

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