BMS 303141
|
- ₹11506.98 - ₹46374.3
- Product name: BMS 303141
- CAS: 943962-47-8
- MF: C19H15Cl2NO4S
- MW: 424.3
- EINECS:
- MDL Number:MFCD25976797
- Synonyms:BMS 303141;BMS30314;3,5-dichloro-2-hydroxy-N-(4-Methoxybiphenyl-3-yl)benzenesulfonaMide;3,5-Dichloro-2-hydroxy-N-(4-methoxy[1,1'-biphenyl]-3-yl)benzenesulfonamide;3,5-Dichloro-2-hydroxy-N-(4-methoxy[1,1'-biphenyl]-3-yl)-benzenesulfonamide BMS 303141;BMS 303141, >=98%;3,5-dichloro-2-hydroxy-N-(2-methoxy-5-phenylphenyl)benzenesulfonamide;CS-887
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberSML0784
- Product descriptionBMS-303141 ≥98% (HPLC)
- Packaging25MG
- Price₹46374.3
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0784
- Product descriptionBMS-303141 ≥98% (HPLC)
- Packaging5MG
- Price₹11506.98
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML0784 | BMS-303141 ≥98% (HPLC) | 25MG | ₹46374.3 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML0784 | BMS-303141 ≥98% (HPLC) | 5MG | ₹11506.98 | 2022-06-14 | Buy |
Properties
Boiling point :591.5±60.0 °C(Predicted)
Density :1.462±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
pka :4.94±0.48(Predicted)
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Density :1.462±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
pka :4.94±0.48(Predicted)
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Safety Information
| Symbol(GHS): |
|
|||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
ATP citrate lyase (ACL) catalyzes the synthesis of acetyl-CoA and oxaloacetate using citrate, CoA, and ATP as substrates and Mg2+ as a cofactor. The ACL-dependent synthesis of acetyl-CoA is important for the de novo synthesis of fatty acids and cholesterol. Furthermore, as a key enzyme for linking glucose and lipid metabolism, ACL is thought to contribute to the Warburg effect in cancer cells. BMS 303141 is a cell-permeable, 2-hydroxy-N-arylbenzenesulfonamide that inhibits ACL with an IC50 value of 0.13 μM. At an oral dose of 100 mg/kg/day, BMS 303141 has been reported to reduce weight gain and lower plasma cholesterol, triglycerides, and glucose in a mouse model of hyperlipidemia.More related product prices
AC480 (BMS-599626) PD-L1 inhibitor 1 468740-43-4 1675201-83-8 BMS813160 XL-652 PALMITOYLETHANOLAMIDE C2 DIHYDROCERAMIDE METYRAPONE JNJ 1661010 BMS-345541 BMS-986020Related product price
- AC480 (BMS-599626)
₹7700-22000 - PALMITOYLETHANOLAMIDE
₹4600-43873.73 - C2 DIHYDROCERAMIDE
₹14100
