PD-L1 inhibitor 1
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- ₹0
- Product name: PD-L1 inhibitor 1
- CAS: 1675203-84-5
- MF: C25H29N3O3
- MW: 419.52
- EINECS:-0
- MDL Number:MFCD29905455
- Synonyms:PD-L1 inhibitor 1;PD1-PDL1 inhibitor 2;N-[2-[[[2-Methoxy-6-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]-3-pyridinyl]methyl]amino]ethyl]acetamide;BMS-202;Acetamide, N-[2-[[[2-methoxy-6-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]-3-pyridinyl]methyl]amino]ethyl]-;PD 1 inhibitor 2;PD1 inhibitor 2;PD-1 inhibitor 2
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Properties
Boiling point :611.4±55.0 °C(Predicted)
Density :1.133±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to at least 25 mg/ml)
pka :16.06±0.46(Predicted)
form :solid
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Density :1.133±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to at least 25 mg/ml)
pka :16.06±0.46(Predicted)
form :solid
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Safety Information
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| Signal word: | Warning | |||||||
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Description
The programmed death-1/programmed death-ligand 1 (PD-1/PD-L1) interaction plays a dominant role in the suppression of T cell responses, especially in a tumor microenvironment, protecting tumor cells from lysis. PD-1/PD-L1 inhibitor 2 is reported to prevent the interaction of PD-L1 with PD-1 with an IC50 value of 18 nM.More related product prices
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