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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Neuronal Signaling >5-HT Receptor Antagonists >Blonanserin

Blonanserin

Blonanserin Structure
  • ₹7800 - ₹33460.08
  • Product name: Blonanserin
  • CAS: 132810-10-7
  • MF: C23H30FN3
  • MW: 367.5
  • EINECS:
  • MDL Number:MFCD00893838
  • Synonyms:6-broMo-4,8-dichloro-5-Methoxyquinoline;Blonansarin –;Blonanserin, AD-5423, Lonasen;Blonanserin-d8 HCl;CYCLOOCTA[B]PYRIDINE, 2-(4-ETHYL-1-PIPERAZINYL)-4-(4-FLUOROPHENYL)-5,6,7,8,9,10-HEXAHYDRO-;Blonanserin;AD 5423;2-(4-Ethyl-1-piperazinyl)-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine
4 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • 100MG
  • ManufacturerTCI Chemicals (India)
  • Product numberB4565
  • Product descriptionBlonanserin
  • Packaging25MG
  • Price₹7800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberB4565
  • Product descriptionBlonanserin
  • Packaging100MG
  • Price₹9800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberB7188
  • Product descriptionBlonanserin ≥98% (HPLC)
  • Packaging25MG
  • Price₹33460.08
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberB7188
  • Product descriptionBlonanserin ≥98% (HPLC)
  • Packaging5MG
  • Price₹8746.6
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) B4565 Blonanserin 25MG ₹7800 2022-05-26 Buy
TCI Chemicals (India) B4565 Blonanserin 100MG ₹9800 2022-05-26 Buy
Sigma-Aldrich(India) B7188 Blonanserin ≥98% (HPLC) 25MG ₹33460.08 2022-06-14 Buy
Sigma-Aldrich(India) B7188 Blonanserin ≥98% (HPLC) 5MG ₹8746.6 2022-06-14 Buy

Properties

Melting point :117-119°C
Boiling point :540.8±50.0 °C(Predicted)
Density :1.095±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO: ≥10mg/mL
form :powder
pka :7.66±0.10(Predicted)
color :white to off-white
Merck :14,1319

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P273 Avoid release to the environment.

Description

Blonanserin is a 4-phenyl-2-(1-piperazinyl) pyridine that acts as an antagonist at dopamine D2, D3, and serotonin 5-HT2A receptors (Kis = 0.14, 0.49, and 0.81 nM, respectively). It binds to 5-HT6 with a Ki value of 11.7 nM and demonstrates relatively low affinity for 5-HT2C (Ki = 26.4 nM), adrenergic α1 (Ki = 26.7 nM), histamine H1 (Ki = 765 nM), and muscarinic M1 receptors (Ki = 100 nM). Blonanserin was developed in Japan as a novel antipsychotic that displays 20- and 94-fold higher affinity for D2 receptors compared to haloperidol and risperidone , respectively.

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