Cidofovir
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- ₹8746.6 - ₹33860.6
- Product name: Cidofovir
- CAS: 113852-37-2
- MF: C8H14N3O6P
- MW: 279.19
- EINECS:638-807-0
- MDL Number:MFCD00866936
- Synonyms:Cidofovir (Vistide);(S)-[1-(4-AMino-2-oxo-pyriMidin-1(2H)-yl)-3-hydroxy-propan-2-yl]oxyMethylphosphonic acid;({[(S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid;Cidofovir(GS-504);(S)-(3-(4-amino-2-oxopyrimidin-1(2H)-yl)-1-hydroxypropan-2-yloxy)methylphosphonic acid;(S)-1-[3-HYDROXY-2-(PHOSPHONYL-METHOXY)PROPYL]-CYTOSINE;(S)-1-(3-HYDROXY-2-PHOSPHONYLMETHOXYPROYPL)CYTOSINE;[1-(4-amino-2-oxo-pyrimidin-1-yl)-3-hydroxy-propan-2-yl]oxymethylphosphonic acid
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 10MG
- 50MG
- ManufacturerSigma-Aldrich(India)
- Product numberC5874
- Product descriptionCidofovir hydrate ≥98% (HPLC)
- Packaging10MG
- Price₹8746.6
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberC5874
- Product descriptionCidofovir hydrate ≥98% (HPLC)
- Packaging50MG
- Price₹33860.6
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | C5874 | Cidofovir hydrate ≥98% (HPLC) | 10MG | ₹8746.6 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C5874 | Cidofovir hydrate ≥98% (HPLC) | 50MG | ₹33860.6 | 2022-06-14 | Buy |
Properties
Melting point :260° (dec)
alpha :D20 -97.3° (c = 0.80 in water)
Boiling point :609.5±65.0 °C(Predicted)
Density :1.76±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :deionized water: ≥5mg/mL (warmed)
form :powder
pka :2.29±0.10(Predicted)
color :White to off-white
Water Solubility :Soluble to 12 mg/mL (42.98 mM) in Water
InChI :InChI=1S/C8H14N3O6P/c9-7-1-2-11(8(13)10-7)3-6(4-12)17-5-18(14,15)16/h1-2,6,12H,3-5H2,(H2,9,10,13)(H2,14,15,16)/t6-/m0/s1
InChIKey :VWFCHDSQECPREK-LURJTMIESA-N
SMILES :P(CO[C@H](CO)CN1C(=O)N=C(N)C=C1)(=O)(O)O
CAS DataBase Reference :113852-37-2(CAS DataBase Reference)
alpha :D20 -97.3° (c = 0.80 in water)
Boiling point :609.5±65.0 °C(Predicted)
Density :1.76±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :deionized water: ≥5mg/mL (warmed)
form :powder
pka :2.29±0.10(Predicted)
color :White to off-white
Water Solubility :Soluble to 12 mg/mL (42.98 mM) in Water
InChI :InChI=1S/C8H14N3O6P/c9-7-1-2-11(8(13)10-7)3-6(4-12)17-5-18(14,15)16/h1-2,6,12H,3-5H2,(H2,9,10,13)(H2,14,15,16)/t6-/m0/s1
InChIKey :VWFCHDSQECPREK-LURJTMIESA-N
SMILES :P(CO[C@H](CO)CN1C(=O)N=C(N)C=C1)(=O)(O)O
CAS DataBase Reference :113852-37-2(CAS DataBase Reference)
Safety Information
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| Signal word: | Danger | |||||||||||||||||||||
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Description
Cidofovir is an acyclic nucleoside phosphonate that is active against herpesvirus (including cytomegalovirus (CMV)), polyomavirus, papillomavirus, adenovirus, and poxvirus infections. In vitro, cidofovir is converted to cidofovir diphosphate which incorporates into viral DNA, selectively inhibiting CMV replication and CMV DNA synthesis with IC50 values of 0.1 μM. Cidofovir has significantly long-lasting antiviral action because of the long half-life of its metabolites whose cellular uptake is slow due to the presence of the negatively charged phosphonate group. The antiviral efficacy of cidofovir has been demonstrated in numerous experimental animal model infections that mirror all major DNA virus infections in humans. It has also demonstrated remarkable activity as an antitumor agent in a variety of animal models of tumor growth.More related product prices
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