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Docetaxel Hydrate

Docetaxel Hydrate Structure
  • ₹0
  • Product name: Docetaxel Hydrate
  • CAS: 700367-34-6
  • MF: C43H53NO14
  • MW: 807.87922
  • EINECS:
  • MDL Number:
  • Synonyms:Paclitaxel Impurity 104;(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-9-(((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-3-phenylpropanoyl)oxy)-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca3,4benzo1,2-boxet-12-yl benzoate hydrate
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :170-174°C
storage temp. :-20°C Freezer
solubility :DMF: 5 mg/ml,DMSO: 5 mg/ml,DMSO:PBS (pH 7.2) (1:10): 0.1 mg/ml,Ethanol: 1.5 mg/ml
form :A crystalline solid

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Docetaxel is a semisynthetic analog of taxol that inhibits microtubule disassembly (IC50 = 0.2 μM) and inhibits cell replication (IC50 = 0.13 μM). It has proven more effective than taxol in preventing the proliferation of cancer cells. Docetaxel has applications in breast cancer and hormone-refractory prostate cancer. This product is intended for research applications.

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Suppliers and manufacturers

CLEARSYNTH LABS LTD. Cayman Chemical Company Shanghai Yifei Biotechnology Co. , Ltd. Toronto Research Chemicals J & K SCIENTIFIC LTD. Shenzhen Polymeri Biochemical Technology Co., Ltd. Shanghai Hao Zhun Biological Technology Co., Ltd.