ML167
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- ₹12946.7
- Product name: ML167
- CAS: 1285702-20-6
- MF: C19H17N3O3
- MW: 335.36
- EINECS:808-432-9
- MDL Number:MFCD27978379
- Synonyms:ML167;ML167/ML-167;5-[4-[[(5-Methyl-2-furanyl)methyl]amino]-6-quinazolinyl]-2-furanmethanol;CID 44968231;5-[4-[[(5-Methyl-2-furanyl)methyl]amino]-6-quinazolinyl]-2-furanmethanol ML167;NCGC00188654;(5-(4-(((5-Methylfuran-2-yl)methyl)amino)quinazolin-6-yl)furan-2-yl)methanol;CID44968231;NCGC00188654
1 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- ManufacturerSigma-Aldrich(India)
- Product numberSML0924
- Product descriptionML167 ≥98% (HPLC)
- Packaging5MG
- Price₹12946.7
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML0924 | ML167 ≥98% (HPLC) | 5MG | ₹12946.7 | 2022-06-14 | Buy |
Properties
Boiling point :531.8±45.0 °C(Predicted)
Density :1.335±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble10mg/mL, clear
pka :13.84±0.10(Predicted)
form :powder
color :off-white to gray to brown
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Density :1.335±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble10mg/mL, clear
pka :13.84±0.10(Predicted)
form :powder
color :off-white to gray to brown
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Safety Information
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Description
The Cdc2-like kinases (Clks) and the dual-specificity tyrosine phosphorylation-regulated kinases (DYRKs) are involved in regulating gene splicing. Clks phosphorylate serine/arginine-rich proteins, which are a major component of the spliceosome, whereas DYRKs interact with and activate splicing factors. ML167 is a selective, ATP-competitive inhibitor of Clk4 with an IC50 value of 136 nM. It is more than 10-fold less active against the closely related kinases Clk1-3, DYRK1A, and DYRK1B (IC50s = 1.5, 1.6, >10, >10, and 4.4 μM, respectively), and minimally active against a panel of other kinases.More related product prices
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