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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Cell Cycle >PLK inhibitors >NMS-P937 (NMS1286937)

NMS-P937 (NMS1286937)

NMS-P937 (NMS1286937) Structure
  • ₹0
  • Product name: NMS-P937 (NMS1286937)
  • CAS: 1034616-18-6
  • MF: C24H27F3N8O3
  • MW: 532.52
  • EINECS:
  • MDL Number:MFCD26793840
  • Synonyms:NMS-1286937;4,5-Dihydro-1-(2-hydroxyethyl)-8-[[5-(4-methyl-1-piperazinyl)-2-(trifluoromethoxy)phenyl]amino]-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide;NMS-P937 (NMS1286937);NMS-P937;NMS-1286937,NMS-P937;1-(2-hydroxyethyl)-8-[5-(4-methylpiperazin-1-yl)-2-(trifluoromethoxy)anilino]-4,5-dihydropyrazolo[4,3-h]quinazoline-3-carboxamide;CS-1243;1H-Pyrazolo[4,3-h]quinazoline-3-carboxamide, 4,5-dihydro-1-(2-hydroxyethyl)-8-[[5-(4-methyl-1-piperazinyl)-2-(trifluoromethoxy)phenyl]amino]-
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Boiling point :757.8±70.0 °C(Predicted)
Density :1.57±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in H2O; insoluble in EtOH; ≥13.33 mg/mL in DMSO
form :solid
pka :14.29±0.10(Predicted)
color :Off-white to light yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

NMS-P937 is a quinazoline derivative that is a potent and selective Polo-like kinase 1 inhibitor. Antitumor, anti-cancer.

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Suppliers and manufacturers

Pharmaffiliates Analytics and Synthetics P. Ltd Pharma Affiliates
ATK CHEMICAL COMPANY LIMITED
Dideu Industries Group Limited
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
Hangzhou MolCore BioPharmatech Co.,Ltd.
Nantong HI-FUTURE Biology Co., Ltd.
TargetMol Chemicals Inc.
Wuhan Topule Biopharmaceutical Co., Ltd