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ChemicalBook > Product Catalogue >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >Narcotine

Narcotine

Narcotine Structure
  • ₹7112.03
  • Product name: Narcotine
  • CAS: 128-62-1
  • MF: C22H23NO7
  • MW: 413.42
  • EINECS:204-899-2
  • MDL Number:MFCD00069316
  • Synonyms:Capval;Coscopin;Coscotabs;dl-Narcotine [dl-form];Gnoscopine [dl-form];Hederix (free base);Key-Tusscapine;l-alpha-2-methyl-8-methoxy-6,7-methylenedioxy-1-(6,7-dimethoxy-3-phthalidyl)-1
2 prices
Selected condition:

Brand

  • Sigma-Aldrich
  • Sigma-Aldrich(India)

Package

  • 5G
  • ManufacturerSigma-Aldrich
  • Product number363960
  • Product description(S,R)-Noscapine 97%
  • Packaging5G
  • Price₹7112.03
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number363960
  • Product description(S,R)-Noscapine 97%
  • Packaging5G
  • Price₹7112.03
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich 363960 (S,R)-Noscapine 97% 5G ₹7112.03 2022-06-14 Buy
Sigma-Aldrich(India) 363960 (S,R)-Noscapine 97% 5G ₹7112.03 2022-06-14 Buy

Properties

Melting point :174-176 °C(lit.)
alpha :-200 º (c=1 in chloroform)
Boiling point :532.6°C (rough estimate)
Density :1.395
refractive index :1.5614 (estimate)
storage temp. :-20°C Freezer, Under Inert Atmosphere
solubility :Practically insoluble in water, soluble in acetone, slightly soluble in ethanol (96 per cent). It dissolves in strong acids; on dilution of the solution with water, the base may be precipitated.
pka :7.8(at 25℃)
color :Orthorhombic prisms or stout needles from alc
optical activity :[α]20/D 200°, c = 1 in chloroform
Water Solubility :302.9mg/L(25 ºC)
Merck :13,6752
NIST Chemistry Reference :Narcotine alkaloid(128-62-1)
EPA Substance Registry System :1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, (3S)- (128-62-1)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
Precautionary statements:

Description

Noscapine may be used as a source to synthesize its bromo-derivatives, which has higher tubulin binding activity when compared to noscapine.Its 3,4,5-trimethoxybenzyl analog is a potential antitumor agent.

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