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ChemicalBook > Product Catalogue >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >Phenylephrine

Phenylephrine

Phenylephrine Structure
  • ₹5100 - ₹13600
  • Product name: Phenylephrine
  • CAS: 59-42-7
  • MF: C9H13NO2
  • MW: 167.21
  • EINECS:200-424-8
  • MDL Number:MFCD00044749
  • Synonyms:component of Dristan cold;component of Dristan nasal mist;component of Entex;component of Histalet forte;component of Hycomine compound;component of Prefrin-a;component of Pv tussin syrup;component of Relief
2 prices
Selected condition:

Brand

  • TCI Chemicals (India)

Package

  • 5G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberP0395
  • Product descriptionL-Phenylephrine
  • Packaging5G
  • Price₹5100
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberP0395
  • Product descriptionL-Phenylephrine
  • Packaging25G
  • Price₹13600
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) P0395 L-Phenylephrine 5G ₹5100 2022-05-26 Buy
TCI Chemicals (India) P0395 L-Phenylephrine 25G ₹13600 2022-05-26 Buy

Properties

Melting point :171°C
Boiling point :295.79°C (rough estimate)
Density :1.1222 (rough estimate)
refractive index :-55.5 ° (C=5, 1mol/L HCl)
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :Slightly soluble in water, sparingly soluble in methanol, slightly soluble in ethanol (96 per cent). It dissolves in dilute mineral acids and in dilute solutions of alkali hydroxides.
pka :pKa 8.9 (Uncertain)
form :Solid
color :White to Off-White
CAS DataBase Reference :59-42-7(CAS DataBase Reference)
NIST Chemistry Reference :Benzenemethanol, 3-hydroxy-«alpha»-[(methylamino)methyl]-, (r)-(59-42-7)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

L-Phenylephrine is an adrenergic α1A receptor agonist (Ki = 1.4 μM) that demonstrates selectivity against the α1B and α1C receptor subtypes (Kis = 23.9 and 47.8 μM, respectively). By stimulating adrenergic α1 receptors, L-phenylephrine can induce aortic smooth muscle contractions, although reported relative affinity and potency values in rabbit are 5-fold weaker compared to that of L-norepinephrine. This compound is frequently used to precontract smooth muscle in preparations designed to study the properties of various vasodilator agents. Because L-phenylephrine acts on adrenergic α1 receptors in the arterioles of the nasal mucosa to produce constriction, it has been examined clinically as an oral decongestant.

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