T0901317
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- ₹6917.18 - ₹18990
- Product name: T0901317
- CAS: 293754-55-9
- MF: C17H12F9NO3S
- MW: 481.33
- EINECS:
- MDL Number:MFCD03412028
- Synonyms:N-(2,2,2-TRIFLUOROETHYL)-N-[4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL]BENZENESULFONAMIDE;T0901317;TO-901317;BenzenesulfonaMide, N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoroMethyl)ethyl]phenyl]-;T 1317;T0901317;T 0901317; T-0901317;N-(2,2,2-Trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl];T0901317 - CAS 293754-55-9 - Calbiochem
3 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 10MG
- ManufacturerSigma-Aldrich(India)
- Product numberT2320
- Product descriptionT0901317 ≥98%
- Packaging5MG
- Price₹6917.18
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberT2320
- Product descriptionT0901317 ≥98%
- Packaging10MG
- Price₹11063.15
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number575310
- Product descriptionT0901317 - CAS 293754-55-9 - Calbiochem A cell-permeable, nonsterol, benzenesulfonamide compound that acts as a highly selective and potent liver X receptor agonist (EC?? of 20 nM for LXRα).
- Packaging10MG
- Price₹18990
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | T2320 | T0901317 ≥98% | 5MG | ₹6917.18 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T2320 | T0901317 ≥98% | 10MG | ₹11063.15 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 575310 | T0901317 - CAS 293754-55-9 - Calbiochem A cell-permeable, nonsterol, benzenesulfonamide compound that acts as a highly selective and potent liver X receptor agonist (EC?? of 20 nM for LXRα). | 10MG | ₹18990 | 2022-06-14 | Buy |
Properties
Melting point :116-118°C
Boiling point :470.5±55.0 °C(Predicted)
Density :1.550±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO (Slightly), Methanol (Slightly)
pka :9.00±0.15(Predicted)
form :Light beige solid
color :Off-White
InChIKey :SGIWFELWJPNFDH-UHFFFAOYSA-N
Boiling point :470.5±55.0 °C(Predicted)
Density :1.550±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO (Slightly), Methanol (Slightly)
pka :9.00±0.15(Predicted)
form :Light beige solid
color :Off-White
InChIKey :SGIWFELWJPNFDH-UHFFFAOYSA-N
Safety Information
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Description
The Liver X Receptors (LXRα and LXRβ) are nuclear hormone receptors whose native ligands are oxysterols, such as 22(R)-hydroxycholesterol. The LXRs regulate the oxysterol-induced expression of cholesterol 7α-hydroxylase, the rate limiting enzyme of classic bile acid synthesis. T0901317 is a potent and selective agonist for both LXRα and LXRβ, with an EC50 of about 50 nM. T0901317 acting through LXR and in concert with its RXR heterodimerization partner induces the expression of the ABCA1 reverse cholesterol transporter. This acts to increase the efflux of cholesterol from enterocytes and thus inhibit the overall absorption of cholesterol.More related product prices
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