ZM 306416
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- ₹0
- Product name: ZM 306416
- CAS: 690206-97-4
- MF: C16H13ClFN3O2
- MW: 333.74
- EINECS:
- MDL Number:MFCD02683969
- Synonyms:ZM 306416 HYDROCHLORIDE;4-[(4'-CHLORO-2'-FLUORO)PHENYLAMINO]-6,7-DIMETHOXYQUINAZOLINE HYDROCHLORIDE;4-QuinazolinaMine,N-(4-chloro-2-fluorophenyl)-6,7-diMethoxy-;ZM306416/ZM-306416;CB 676475;CB-676475;ZM 213689 DisodiuM Salt (MeropeneM iMpurity) (Mixture of double bond isoMers);N-(4-Chloro-2-fluorophenyl)-6,7-dimethoxy-4-quinazolinamine
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Properties
Melting point :>161°C (dec.)
Boiling point :434.1±45.0 °C(Predicted)
Density :1.389±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :Methanol (Slightly), Water (Sparingly)
form :Off-white solid.
pka :5.49±0.30(Predicted)
color :Light Orange to Brown
Stability :Hygroscopic
Boiling point :434.1±45.0 °C(Predicted)
Density :1.389±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :Methanol (Slightly), Water (Sparingly)
form :Off-white solid.
pka :5.49±0.30(Predicted)
color :Light Orange to Brown
Stability :Hygroscopic
Safety Information
Symbol(GHS): |
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Description
ZM 306416 is an inhibitor of vascular endothelial growth factor (VEGF) receptor tyrosine kinase that antagonizes the activity of KDR and Flt VEGF receptors with IC50 values of 100 nM and 2 μM, respectively. It has also been reported to inhibit EGFR kinase with an IC50 value of < 10 nM, reducing proliferation of EGFR-dependent cancer cells.Related product price
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