Abiraterone
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- ₹3200 - ₹9700
- Product name: Abiraterone
- CAS: 154229-19-3
- MF: C24H31NO
- MW: 349.52
- EINECS:810-941-6
- MDL Number:MFCD00924100
- Synonyms:abiraterone;Cb 7598;Unii-G819A456D0;Abiraterone(CB-7598);17-(3-Pyridyl)androsta-5,16-dien-3beta-ol;Aberration;ABT 17-(3-pyridyl)androsta-5,16-dien-3β-ol abiraterone;(3b)-17-(3-pyridinyl)-Androsta-5,16-dien-3-ol
2 prices
Selected condition:
Brand
- TCI Chemicals (India)
Package
- 20MG
- 200MG
- ManufacturerTCI Chemicals (India)
- Product numberA2868
- Product descriptionAbiraterone
- Packaging20MG
- Price₹3200
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberA2868
- Product descriptionAbiraterone
- Packaging200MG
- Price₹9700
- Updated2022-05-26
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | A2868 | Abiraterone | 20MG | ₹3200 | 2022-05-26 | Buy |
TCI Chemicals (India) | A2868 | Abiraterone | 200MG | ₹9700 | 2022-05-26 | Buy |
Properties
Melting point :227-228 °C(Solv: toluene (108-88-3))
Boiling point :500.2±50.0 °C(Predicted)
Density :1.14±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Chloroform (Slightly), Methanol (Slightly)
form :Solid
pka :14.71±0.70(Predicted)
color :White to Pale Yellow
CAS DataBase Reference :154229-19-3
Boiling point :500.2±50.0 °C(Predicted)
Density :1.14±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Chloroform (Slightly), Methanol (Slightly)
form :Solid
pka :14.71±0.70(Predicted)
color :White to Pale Yellow
CAS DataBase Reference :154229-19-3
Safety Information
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Description
Abiraterone is a new type of hormone therapy. It is also called abiraterone acetate, CB7630 or Zytiga. It is used to treat prostate cancer that has spread to other parts of the body. It may help some men to live longer. It can also help control symptoms. Clinical trials are also using abiraterone for earlier stages of prostate cancer and advanced breast cancer. Abiraterone is associated with a not uncommon rate of serum enzyme elevation during therapy, but has not been clearly linked to cases of clinically apparent liver injury with jaundice.On April 28, 2011, the U.S. Food and Drug Administration approved abiraterone acetate (Zytiga Tablets, Centocor Ortho Biotech, Inc.) for use in combination with prednisone for the treatment of patients with metastatic castration-resistant prostate cancer (mCRPC) who have received prior chemotherapy containing docetaxel.
Abiraterone is a steroidal compound with antiandrogen activity. it is a Cytochrome P450 17A1 Inhibitor. The mechanism of action of abiraterone is as a Cytochrome P450 17A1 Inhibitor, and Cytochrome P450 2D6 Inhibitor, and Cytochrome P450 2C8 Inhibitor that catalyzes the 17alpha-hydroxylation of steroid intermediates involved in testosterone synthesis. Administration of this agent may suppress testosterone production by both the testes and the adrenals to castrate-range levels.
figure 1: Zytiga (abiraterone acetate)
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