BETA-LAPACHONE
- ₹17146.8
- Product name: BETA-LAPACHONE
- CAS: 4707-32-8
- MF: C15H14O3
- MW: 242.27
- EINECS:
- MDL Number:MFCD01712233
- Synonyms:BETA-LAPACHONE;2-b)pyran-5,6-dione,3,4-dihydro-2,2-dimethyl-2h-naphtho( ;B-LAPACHONE,2,2-DIMETHYL-3,4-DIHYDRO-2H-BENZO[H]CHROMENE-5,6-DIONE;3,4-DIHYDRO-2,2-DIMETHYL-2H-NAPHTHO[1,2-B]PYRAN-5,6-DIONE;3,4-DIHYDRO-2,2-DIMETHYL-2H-NAPHTHOL[1,2-B]PYRAN-5,6-DIONE;2,2-Dimethyl-3,4,5,6-tetrahydro-2H-naphtho[1,2-b]pyran-5,6-dione;2,2-dimethyl-3,4-dihydrobenzo[h]chromene-5,6-dione;β-Lapachone (90%)
1 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- ManufacturerSigma-Aldrich(India)
- Product numberL2037
- Product descriptionβ-Lapachone ≥98% (TLC)
- Packaging5MG
- Price₹17146.8
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | L2037 | β-Lapachone ≥98% (TLC) | 5MG | ₹17146.8 | 2022-06-14 | Buy |
Properties
Melting point :>110°C (dec.)
Boiling point :381.4±42.0 °C(Predicted)
Density :1.25±0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,Room Temperature
solubility :Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 15 mg/ml)
form :Orange to brown solid.
color :Orange
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code
InChIKey :QZPQTZZNNJUOLS-UHFFFAOYSA-N
LogP :2.820 (est)
Boiling point :381.4±42.0 °C(Predicted)
Density :1.25±0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,Room Temperature
solubility :Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 15 mg/ml)
form :Orange to brown solid.
color :Orange
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code
InChIKey :QZPQTZZNNJUOLS-UHFFFAOYSA-N
LogP :2.820 (est)
Safety Information
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Description
β-Lapachone is a natural quinone with diverse anti-cancer and anti-inflammatory effects. It inhibits topoisomerase I at 25 μM and transglutaminase (IC50 = 5 μM). In cancer cells which overexpress NAD(P)H:quinone oxidoreductase, β-lapachone is reduced to β-lapachone hydroquinone, which generates reactive oxygen species during its reversion to β-lapachone. This process sensitizes cancer cells to radiation, suppresses NF-κB activation, and drives apoptosis.More related product prices
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