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CILOSTAMIDE

CILOSTAMIDE Structure
  • ₹22027 - ₹39500.43
  • Product name: CILOSTAMIDE
  • CAS: 68550-75-4
  • MF: C20H26N2O3
  • MW: 342.43
  • EINECS:
  • MDL Number:MFCD00673958
  • Synonyms:OPC 3689;OCP 3689;N-CYCLOHEXYL-N-METHYL-4-(1,2-DIHYDRO-2-OXO-6-QUINOLYLOXY)BUTYRAMIDE;CILOSTAMIDE;Cilostamide,OPC 3689;ciloalaMide;6-[3-(N-Cyclohexyl-N-methylcarbamoyl)propoxy]quinolin-2[1H]-one;N-Cyclohexyl-4-[(1,2-dihydro-2-oxoquinolin-6-yl)oxy]-N-methylbutanamide
3 prices
Selected condition:

Brand

  • ALFA India
  • Sigma-Aldrich(India)

Package

  • 5MG
  • 10mg
  • ManufacturerALFA India
  • Product numberALF-J65319-MA
  • Product descriptionCilostamide
  • Packaging10mg
  • Price₹22027
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number231085
  • Product descriptionCilostamide - CAS 68550-75-4 - Calbiochem A cell-permeable selective inhibitor of cGMP-inhibited phosphodiesterase (PDE III; IC?? = 70 nM).
  • Packaging10MG
  • Price₹27450.01
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC7971
  • Product descriptionCilostamide phosphodiesterase inhibitor
  • Packaging5MG
  • Price₹39500.43
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ALFA India ALF-J65319-MA Cilostamide 10mg ₹22027 2022-05-26 Buy
Sigma-Aldrich(India) 231085 Cilostamide - CAS 68550-75-4 - Calbiochem A cell-permeable selective inhibitor of cGMP-inhibited phosphodiesterase (PDE III; IC?? = 70 nM). 10MG ₹27450.01 2022-06-14 Buy
Sigma-Aldrich(India) C7971 Cilostamide phosphodiesterase inhibitor 5MG ₹39500.43 2022-06-14 Buy

Properties

Melting point :186~188℃
Boiling point :594.3±50.0 °C(Predicted)
Density :1.18±0.1 g/cm3(Predicted)
storage temp. :0-6°C
solubility :Soluble in DMSO (up to 30 mg/ml).
form :White solid
pka :11.12±0.70(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Cilostamide is a selective inhibitor of phosphodiesterase (PDE)3A and PDE3B with IC50 values of 27 and 50 nM, respectively. It is less selective for inhibition of PDE1, PDE2, PDE4, PDE5, and PDE7 (IC50s = 12 to > 300 μM). Cilostamide has been shown to inhibit thrombin-induced platelet aggregation with an IC50 value of 1.1 μM.

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