Lovastatin
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- ₹8042.98 - ₹22440.23
- Product name: Lovastatin
- CAS: 75330-75-5
- MF: C24H36O5
- MW: 404.54
- EINECS:616-212-7
- MDL Number:MFCD00072164
- Synonyms:SiMvastatin EP IMpurity E;8-[2-(4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-1-nap;6alpha-Methylcompactin Mevinolin Monacolin K;)ethyl]-1-naphthalenylester ;[1s-[1alpha(r*),3alpha,7beta,8beta(2s*,4s*),8abeta]]-2-methylbutanoicacid1,2, ;1,2,6,7,8,8a-hexahydro-beta,delta-dihydroxy-2,6-dimethyl-8-(2-methyl-1-oxobuty ;2-methyl-,1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(tetrahydro-butanoicaci ;3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2h-pyran-2-yl
6 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
- Sigma-Aldrich
- TCI Chemicals (India)
Package
- 25MG
- 1G
- 5G
- 25G
- ManufacturerSigma-Aldrich(India)
- Product numberM2147
- Product descriptionMevinolin from Aspergillus sp. ≥98% (HPLC)
- Packaging25MG
- Price₹22440.23
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number438185
- Product descriptionLovastatin - CAS 75330-75-5 - Calbiochem Lovastatin, CAS 75330-75-5, is an anti-hypercholesterolemic agent that inhibits the activity of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reduct
- Packaging25MG
- Price₹20710
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberPHR1285
- Product descriptionLovastatin Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging1G
- Price₹8042.98
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich
- Product number438185
- Product descriptionLovastatin - CAS 75330-75-5 - Calbiochem Lovastatin, CAS 75330-75-5, is an anti-hypercholesterolemic agent that inhibits the activity of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase.
- Packaging25MG
- Price₹20710
- Updated2022-06-14
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberL0214
- Product descriptionLovastatin
- Packaging25G
- Price₹13200
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberL0214
- Product descriptionLovastatin
- Packaging5G
- Price₹9000
- Updated2022-05-26
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | M2147 | Mevinolin from Aspergillus sp. ≥98% (HPLC) | 25MG | ₹22440.23 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 438185 | Lovastatin - CAS 75330-75-5 - Calbiochem Lovastatin, CAS 75330-75-5, is an anti-hypercholesterolemic agent that inhibits the activity of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reduct | 25MG | ₹20710 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | PHR1285 | Lovastatin Pharmaceutical Secondary Standard; Certified Reference Material | 1G | ₹8042.98 | 2022-06-14 | Buy |
Sigma-Aldrich | 438185 | Lovastatin - CAS 75330-75-5 - Calbiochem Lovastatin, CAS 75330-75-5, is an anti-hypercholesterolemic agent that inhibits the activity of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase. | 25MG | ₹20710 | 2022-06-14 | Buy |
TCI Chemicals (India) | L0214 | Lovastatin | 25G | ₹13200 | 2022-05-26 | Buy |
TCI Chemicals (India) | L0214 | Lovastatin | 5G | ₹9000 | 2022-05-26 | Buy |
Properties
Melting point :175°C
alpha :D25 +323° (c = 0.5 g in 100 ml acetonitrile)
Boiling point :559.2±50.0 °C(Predicted)
Density :1.12±0.1 g/cm3(Predicted)
vapor pressure :0Pa at 25℃
refractive index :320 ° (C=0.5, CH3CN)
storage temp. :-20°C
solubility :ethanol: soluble9.80-10.20mg/mL, clear, colorless to faintly yellow
pka :13.49±0.40(Predicted)
form :White to off-white powder
color :White
Water Solubility :0.0004 mg/mL at 25 ºC
Merck :14,5586
BCS Class :2
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
LogP :4.260
CAS DataBase Reference :75330-75-5(CAS DataBase Reference)
EPA Substance Registry System :Lovastatin (75330-75-5)
alpha :D25 +323° (c = 0.5 g in 100 ml acetonitrile)
Boiling point :559.2±50.0 °C(Predicted)
Density :1.12±0.1 g/cm3(Predicted)
vapor pressure :0Pa at 25℃
refractive index :320 ° (C=0.5, CH3CN)
storage temp. :-20°C
solubility :ethanol: soluble9.80-10.20mg/mL, clear, colorless to faintly yellow
pka :13.49±0.40(Predicted)
form :White to off-white powder
color :White
Water Solubility :0.0004 mg/mL at 25 ºC
Merck :14,5586
BCS Class :2
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
LogP :4.260
CAS DataBase Reference :75330-75-5(CAS DataBase Reference)
EPA Substance Registry System :Lovastatin (75330-75-5)
Safety Information
Symbol(GHS): |
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Signal word: | Warning | ||||||||||||||
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Description
Lovastatin is a cholesterol lowering drug and competitive inhibitor of HMG-CoA reductase, a rate limiting enzyme in cholesterol synthesis. Blocks the production of mevalonate, a critical compound in the production of cholesterol and isoprenoids. It increases cellular resistance to anticancer agents such as doxorubicin and induces apoptosis in myeloma cells. It causes cell cycle arrest in G1 and G2/M phases.More related product prices
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