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ChemicalBook > Product Catalogue >API >Nervous system drugs >Parkinson's disease drugs >Pramipexole Impurity 4

Pramipexole Impurity 4

Pramipexole Impurity 4 Structure
  • ₹9428.58 - ₹38461.23
  • Product name: Pramipexole Impurity 4
  • CAS: 104632-25-9
  • MF: C10H19Cl2N3S
  • MW: 284.25
  • EINECS:629-842-2
  • MDL Number:MFCD00876894
  • Synonyms:PRAMIPEXOLE HCL;PRAMIPEXOL HCL;(s)-2-amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole dihydrochloride;PramipexoleDihcl;(S)-2-Amino-6-(propylamino)-4,5,6,7-tetrahydrobenzothiazol2HCltetrahydrobenzothiazol;(s)-4,5,6,7-Tetrahydro-N6-propyl-2,6-benzothiazolediamine, Dihydrochloride;Pramipexole dihydrochloride (S)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole dihydrochloride;PraMipexole dihydrochlor
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberA1237
  • Product descriptionPramipexole dihydrochloride >98% (HPLC), powder
  • Packaging10MG
  • Price₹9428.58
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA1237
  • Product descriptionPramipexole dihydrochloride >98% (HPLC), powder
  • Packaging50MG
  • Price₹38461.23
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) A1237 Pramipexole dihydrochloride >98% (HPLC), powder 10MG ₹9428.58 2022-06-14 Buy
Sigma-Aldrich(India) A1237 Pramipexole dihydrochloride >98% (HPLC), powder 50MG ₹38461.23 2022-06-14 Buy

Properties

Melting point :288-290°C
storage temp. :2-8°C
solubility :H2O: >20mg/mL
form :powder
color :white to off-white
InChIKey :QMNWXHSYPXQFSK-KLXURFKVSA-N
CAS DataBase Reference :104632-25-9(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

Description

Pramipexole is an agonist of the Gαi-linked dopamine receptors D2, D3, and D4 (Ki = 3.9, 2.2, 0.5, and 5.1 nM for D2S, D2L, D3, and D4, respectively). It is relatively inactive at the Gαs-linked dopamine receptors D1 and D5, as well as at serotonin and adrenergic receptors. This narrow profile of receptor binding distinguishes pramipexole from other compounds, particularly those derived from ergot fungi, which can be associated with adverse events when used for treating Parkinson’s disease and other disorders. Pramipexole undergoes almost no hepatic metabolism and exerts no potent inhibition of cytochrome P450 isoforms in vitro.

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SNA HEALTHCARE PVT LTD Varanous Labs Pvt Ltd PANCHSHEEL ORGANICS LTD Hetero Drugs Limited Macleods Pharmaceuticals Limited Unichem Laboratories Ltd Orchid Pharma Ltd. (Formerly Known as Orchid Chemicals and Pharmaceuticals Ltd.) Rivashaa Agrotech Biopharma Pvt. Ltd. Mylan Laboratories Ltd Ralington Pharma