RADICICOL
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- ₹14260 - ₹70449.1
- Product name: RADICICOL
- CAS: 12772-57-5
- MF: C18H17ClO6
- MW: 364.78
- EINECS:
- MDL Number:MFCD06795865
- Synonyms:(1AR,2Z,4E,14R,15AR)-8-CHLORO-1A,14,15,15A-TETRAHYDRO-9,11-DIHYDROXY-14-METHYL-6H-OXIRENO[E][2]BENZOXACYCLOTETRADECIN-6,12(7H)-DIONE;[1AS-(1AR*,2Z,4E,14*,15AR*)]-8-CHLORO-1A,14,15,15A-TETRAHYDRO-9,11-DIHYDROXY-14-METHYL-6H-OXIRENO[E][2]BENZOXACYCLOTETRADECIN-6,12(7H)-DIONE;5-CHLORO-6-(7,8-EPOXY-10-HYDROXY-2-OXO-3,5-UNDECADIENYL)-BETA-RESORCYLIC ACID MU-LACTONE;FO-4910;KF58332;KF9-A;MONORDEN;MONORODENE
3 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 1MG
- 5MG
- 500μG
- ManufacturerSigma-Aldrich(India)
- Product number553400
- Product descriptionRadicicol, Diheterospora chlamydosporia - CAS 12772-57-5 - Calbiochem
- Packaging500μG
- Price₹14260
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberR2146
- Product descriptionRadicicol from Diheterospora chlamydosporia solid
- Packaging1MG
- Price₹17601.45
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberR2146
- Product descriptionRadicicol from Diheterospora chlamydosporia solid
- Packaging5MG
- Price₹70449.1
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 553400 | Radicicol, Diheterospora chlamydosporia - CAS 12772-57-5 - Calbiochem | 500μG | ₹14260 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | R2146 | Radicicol from Diheterospora chlamydosporia solid | 1MG | ₹17601.45 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | R2146 | Radicicol from Diheterospora chlamydosporia solid | 5MG | ₹70449.1 | 2022-06-14 | Buy |
Properties
Melting point :193.5°
alpha :D20 +203° (chloroform)
Boiling point :656.2±55.0 °C(Predicted)
Density :1.364±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :ethanol: 10 mg/mL
form :solid
pka :6.29±0.40(Predicted)
color :yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
alpha :D20 +203° (chloroform)
Boiling point :656.2±55.0 °C(Predicted)
Density :1.364±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :ethanol: 10 mg/mL
form :solid
pka :6.29±0.40(Predicted)
color :yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Safety Information
Symbol(GHS): |
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Description
Radicicol is a natural product derived from D. chlamydosporia with antibiotic, antifungal, and antimalarial properties. It binds and inhibits heat shock protein 90 (Hsp90) with nanomolar affinity. This interaction inhibits p23 from associating with Hsp90, suppresses signaling through HIF-1α, and produces decreased levels of progesterone receptor, Raf-1, p185erb82, and mutant p53. Radicicol also binds to and inhibits DNA topoisomerase type II proteins and GRP94 through an ATPase domain common to Hsp90.Related product price
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