tasquinimod
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- Product name: tasquinimod
- CAS: 254964-60-8
- MF: C20H17F3N2O4
- MW: 406.36
- EINECS:
- MDL Number:MFCD18251454
- Synonyms:4-Hydroxy-5-methoxy-N-methyl-1-methyl-2-oxo-N-(4-trifluoromethylphenyl)-1,2-dihydroquinoline-3-carboxamide;N-Methyl-N-(4-trifluoromethylphenyl)-1,2-dihydro-4-hydroxy-5-methoxy-1-methyl-2-oxoquinoline-3-carboxamide;tasquinimod;ABR-215050;3-QuinolinecarboxaMide, 1,2-dihydro-4-hydroxy-5-Methoxy-N,1-diMethyl-2-oxo-N-[4-(trifluoroMethyl)phenyl]-;4-Hydroxy-5-Methoxy-1-Methyl-2-oxo-1,2- dihydro-quinoline-3-carboxylic acid Methyl- (4-trifluoroMethyl-phenyl)-aMide;1,2-dihydro-4-hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-[4-trifluoromethyl)phenyl]-3-quinolinecarboxamide;4-Hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-(4-(trifluoromethyl)-phenyl)-1,2-dihydroquinoline-3-c
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Properties
Boiling point :501.5±50.0 °C(Predicted)
Density :1.427±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :insoluble in H2O; ≥20.32 mg/mL in DMSO; ≥4.75 mg/mL in EtOH with gentle warming and ultrasonic
form :solid
pka :4.50±1.00(Predicted)
color :White to light yellow
Density :1.427±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :insoluble in H2O; ≥20.32 mg/mL in DMSO; ≥4.75 mg/mL in EtOH with gentle warming and ultrasonic
form :solid
pka :4.50±1.00(Predicted)
color :White to light yellow
Safety Information
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Description
Tasquinimod is an orally-active quinoline-3-carboxamide derived from roquinimex, an immunomodulatory quinolone with applications in some cancers and autoimmune diseases. Tasquinimod inhibits tumor angiogenesis and supplements radiation or chemotherapy in animal models of prostate cancer. While its precise mechanism of action remains unclear, tasquinimod has been reported to alter signaling through S100A9, thrombospondin-1, HIF-1α, androgen receptor, VEGF, and HDAC3/4.More related product prices
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- Fingolimod hydrochloride
₹7068.73-100932.3 - CIVENTICHEM CV-4057
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₹3500-42877.83
