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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Epigenetics >Epigenetic Reader Domain antagonist >UNC-1215

UNC-1215

UNC-1215 Structure
  • ₹11842.55 - ₹47413.5
  • Product name: UNC-1215
  • CAS: 1415800-43-9
  • MF: C32H43N5O2
  • MW: 529.72
  • EINECS:
  • MDL Number:MFCD22683289
  • Synonyms:UNC 1215;UNC1215;UNC-1215;(2-(phenylaMino)-1,4-phenylene)bis((4-(pyrrolidin-1-yl)piperidin-1-yl)Methanone);1,1'-[2-(Phenylamino)-1,4-phenylene]bis[1-[4-(1-pyrrolidinyl)-1-piperidinyl]methanone];UNC 1215, >=98%;UNC1215 1,1'-[2-(PhenylaMino)-1,4-phenylene]bis[1-[4-(1-pyrrolidinyl)-1-piperidinyl]Methanone];Methanone, 1,1'-[2-(phenylamino)-1,4-phenylene]bis[1-[4-(1-pyrrolidinyl)-1-piperidinyl]-
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0662
  • Product descriptionUNC1215 ≥98% (HPLC)
  • Packaging5MG
  • Price₹11842.55
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0662
  • Product descriptionUNC1215 ≥98% (HPLC)
  • Packaging25MG
  • Price₹47413.5
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML0662 UNC1215 ≥98% (HPLC) 5MG ₹11842.55 2022-06-14 Buy
Sigma-Aldrich(India) SML0662 UNC1215 ≥98% (HPLC) 25MG ₹47413.5 2022-06-14 Buy

Properties

Boiling point :712.1±60.0 °C(Predicted)
Density :1.224±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear
pka :9.90±0.20(Predicted)
form :powder
color :white to beige

Safety Information

Symbol(GHS):
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Hazard statements:
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Description

Methyllysine (Kme) recognition “reader” domains play a central role in epigenetic regulation during cellular differentiation, development, and gene transcription. UNC1215 is a potent and selective chemical probe for the Kme reading function of L3MBTL3, a member of the malignant brain tumor (MBT) family of chromatin interacting transcriptional repressors. UNC1215 binds L3MBTL3 with a Kd value of 120 nM (IC50 = 40 nM), competitively displacing mono- or dimethyl-lysine containing peptides. This probe is greater than 50-fold selective toward L3MBTL3 than other members of the human MBT family and demonstrates selectivity against more than 200 other Kme reader domains examined. See the Structural Genomics Consortium (SGC) website for more information.

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