Linolenic acid
- CAS No.
- 463-40-1
- Chemical Name:
- Linolenic acid
- Synonyms
- α-Linolenic acid;ALPHA-LINOLENIC ACID;9,12,15-OCTADECATRIENOIC ACID;linolenic;a-Linolenic acid;OCTADECA-9Z,12Z,15Z-TRIENOIC ACID;(Z,Z,Z)-9,12,15-Octadecatrienoic acid;ALPHA-LNN;A-linolenic;α-linolenic acid (ALA)
- CBNumber:
- CB2112323
- Molecular Formula:
- C18H30O2
- Molecular Weight:
- 278.43
- MOL File:
- 463-40-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/5/14 14:12:18
| Melting point | -11 °C(lit.) |
|---|---|
| Boiling point | 230-232 °C1 mm Hg(lit.) |
| Density | 0.914 g/mL at 25 °C(lit.) |
| FEMA | 3380 | 9,12-OCTADECADIENOIC ACID (48%) AND 9,12,15-OCTADECATRIENOIC ACID (52%) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform, Ethyl Acetate (Slightly), Methanol (Slightly) |
| pka | 4.78±0.10(Predicted) |
| form | Liquid |
| color | Clear colorless to light yellow |
| Specific Gravity | 0.91 |
| Odor | faint fatty |
| Water Solubility | INSOLUBLE |
| Merck | 14,5506 |
| BRN | 1727693 |
| InChIKey | DTOSIQBPPRVQHS-PDBXOOCHSA-N |
| LogP | 6.52 |
| CAS DataBase Reference | 463-40-1(CAS DataBase Reference) |
| NIST Chemistry Reference | 9,12,15-Octadecatrienoic acid, (Z,Z,Z)-(463-40-1) |
| EPA Substance Registry System | Linolenic acid (463-40-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H319 | |||||||||
| Precautionary statements | P210-P305+P351+P338-P370+P378-P403+P235 | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| RIDADR | UN1170 - class 3 - PG 2 - Ethanol | |||||||||
| WGK Germany | 1 | |||||||||
| F | 8-10-23 | |||||||||
| HS Code | 29161500 | |||||||||
| NFPA 704 |
|
Linolenic acid price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | L2376 | Linolenic acid ≥99% | 463-40-1 | 500MG | ₹9331.15 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | L2376 | Linolenic acid ≥99% | 463-40-1 | 5G | ₹57859.63 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | L2376 | Linolenic acid ≥99% | 463-40-1 | 10G | ₹90962.48 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 62170 | Linolenic acid ~70% (GC) | 463-40-1 | 10ML | ₹11290.48 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | L-039 | alpha-Linolenic acid 1.0?mg/mL in ethanol, certified reference material, Cerilliant? | 463-40-1 | 1ML | ₹13579.3 | 2022-06-14 | Buy |
Linolenic acid Chemical Properties,Uses,Production
Description
Linolenic acid (LA), also known as Alpha-linolenic acid (ALA), is an omega-3 essential fatty acid with a wide range of biological activities such as cardiovascular protection, anticancer, neuroprotection, anti-osteoporosis, anti-inflammatory, and antioxidant.LA is mainly sourced from plants, such as nuts and seeds, and is used for the endogenous synthesis of LC omega-6 fatty acids. It is used medicinally as a nutritional supplement and to treat dietary deficiencies or imbalances.
Chemical Properties
clear light yellow to yellow liquid
Occurrence
linolenic acid occurs as the glyceride in many seed fats. It is an essential fatty acid in the diet.
Uses
linolenic acid is also known as alpha-linolenic acid; omega-3. An essential fatty acid found in most drying oils. It is slightly irritating to the mucous membranes. It may be used in a cosmetic preparation for any of the following broad uses: anti-static, cleansing, emollient, skin-conditioning, and surfactant properties.
Definition
ChEBI: Alpha-linolenic acid is a linolenic acid with cis-double bonds at positions 9, 12 and 15. Shown to have an antithrombotic effect. It has a role as a micronutrient, a nutraceutical and a mouse metabolite. It is an omega-3 fatty acid and a linolenic acid. It is a conjugate acid of an alpha-linolenate and a (9Z,12Z,15Z)-octadeca-9,12,15-trienoate.
benefits
Linolenic acid (LA) is an essential fatty acid with anti-inflammatory, anti-bacterial, anti-atherosclerotic and anti-cancer activities, and has a variety of health benefits, including: lowering high blood pressure and cholesterol, lowering the risk of heart disease, maintaining the membrane fluidity of the epidermal transdermal water barrier, improving the barrier function of the skin, decreasing inflammation, regulating sebum secretion, moisturising the scalp, promoting hair growth and prevents hair breakage. It also has a whitening effect on over-pigmented skin.
General Description
Linolenic acid is a clear colorless liquid. (NTP, 1992)
Air & Water Reactions
Oxidizes in air to form peroxides, which spontaneously ignite. Insoluble in water. Sensitive to heat and moisture.
Reactivity Profile
Linolenic acid is incompatible with bases, oxidizing agents and reducing agents. Also incompatible with peroxides, oxygen and water.
Fire Hazard
Linolenic acid is probably combustible.
Carcinogenicity
Narisawa et al. found that diets high in perilla oil (with high a-linolenic acid but also high levels of linoleic acid) lowered the risk of colon cancer in a rat model initiated with the carcinogen N-methyl-Nnitrosourea. Okuno found a suppressive effect on diethylnitrosamine- induced heptaocarcinogenesis in male Fischer 344 rats treated with either safflower (high in linoleic acid) or perilla oil (high in both linoleic and α-linolenic acids). Kitano et al. found that 10% α-linolenic acid did not promote urninary bladder cancer initiated in rats with N-butyl-N-(4-hydrocybutyl)nitrosamine. Mice fed a-linolenic acid at 5–10% of the diet had increased mammary gland ductular cell proliferation.
Linolenic acid Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| Clearsynth Labs | 91-22-45045900 | Maharashtra, India | 3889 | 58 | Inquiry |
| Argos International | 08048372395Ext 118 | Mumbai, India | 154 | 58 | Inquiry |
| CLEANCHEM LABORATORIES LLP | +91 98921 69560 | New Delhi, India | 326 | 58 | Inquiry |
| Asiel Chempharma | 91-9920082277 | Maharashtra, India | 119 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| CLEARSYNTH LABS LTD. | 58 |
| CHEMSWORTH | 30 |
| A.J Chemicals | 58 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| Triveni chemicals | 58 |
| SynZeal Research Pvt Ltd | 58 |
| Clearsynth Labs | 58 |
| Argos International | 58 |
| CLEANCHEM LABORATORIES LLP | 58 |
| Asiel Chempharma | 58 |
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