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ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Cytoskeletal Signaling >HSP e.g. HSP90 inhibitors >6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine

6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine

6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine Structure
CAS No.
873436-91-0
Chemical Name:
6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine
Synonyms
CS-105;PU-H 71;NSC 750424;PU-H71 XHBr;PU-H71, >=98%;Zelavespib (PU-H71);PU-H71, 10 mM in DMSO;PU-H71 Trifluoroacetic Acid;9-(3-(Dimethylamino)propyl)-8-((6-iodobenzo[d][1,3]dioxol-5-yl)thio)-9H-purin-6-amine;8-[(6-iodo-1,3-benzodioxol-5-yl)sulfanyl]-9-[3-(propan-2-ylamino)propyl]purin-6-amine
CBNumber:
CB42554288
Molecular Formula:
C18H21IN6O2S
Molecular Weight:
512.37
MOL File:
873436-91-0.mol
MSDS File:
SDS
Modify Date:
2024/11/19 20:33:22
Request For Quotation

6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine Properties

Melting point >194oC (dec.)
Boiling point 650.6±65.0 °C(Predicted)
Density 1.84
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility DMSO (Slightly), Methanol (Slightly)
pka 10.16±0.29(Predicted)
form Solid
color Off-White to Pale Beige

6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine Chemical Properties,Uses,Production

Uses

Trifluoroacetic Acid of PU-H71 is a potent Hsp90 inhibitor (IC50 = 50 nM). Hsp90 plays a critical role in modulating the activity of many cell signaling proteins and are an attractive target for anti-cancer therapeutics. Studies indicate that Hsp90 inhibitors may serve as potential anti-Parkinson′s disease.

6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine Preparation Products And Raw materials

Raw materials

Preparation Products

6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine Suppliers

Global( 135)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6257 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49732 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 32202 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30230 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 22854 58 Inquiry
Finetech Industry Limited +86-27-8746-5837 +8619945049750 China 9642 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10473 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6391 58 Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd +8618327326525 China 8467 58 Inquiry
Zibo Hangyu Biotechnology Development Co., Ltd +86-0533-2185556 +8615965530500 China 10983 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
CONIER CHEM AND PHARMA LIMITED 58
TargetMol Chemicals Inc. 58
Career Henan Chemica Co 58
Dideu Industries Group Limited 58
Finetech Industry Limited 58
Zhejiang J&C Biological Technology Co.,Limited 58
InvivoChem 58
Wuhan Topule Biopharmaceutical Co., Ltd 58
Zibo Hangyu Biotechnology Development Co., Ltd 58

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6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine 8-((6-iodobenzo[d][1,3]dioxol-5-yl)thio)-9-(3-(isopropylaMino)propyl)-9H-purin-6-aMine PU-H71 Trifluoroacetic Acid 9H-Purine-9-propanamine, 6-amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)- NSC 750424 6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine PU-H71 Trifluoroacetic Acid PU-H71, >=98% 8-[(6-iodo-1,3-benzodioxol-5-yl)sulfanyl]-9-[3-(propan-2-ylamino)propyl]purin-6-amine 9-(3-(Dimethylamino)propyl)-8-((6-iodobenzo[d][1,3]dioxol-5-yl)thio)-9H-purin-6-amine PU-H 71 CS-105 6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine USP/EP/BP Zelavespib (PU-H71) PU-H71 XHBr PU-H71, 10 mM in DMSO 873436-91-0 C18H21IN6O2S API Inhibitors