ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Pyridine compound >Fluoropyridine >3-Amino-5-fluoropyridine
3-Amino-5-fluoropyridine
- CAS No.
- 210169-05-4
- Chemical Name:
- 3-Amino-5-fluoropyridine
- Synonyms
- 5-Fluoropyridin-3-amine;5-Fluoro-3-pyridinamine;3-AMINO-5-FLUOROPYRIDINE;3-PyridinaMine,5-fluoro-;3-Amine-5-fluoro-pyridin;5-Fluoropyridin-3-ylamine;3-AMine-5-fluoro-pyridine;3-Amino-5-fluoropyridine >3-aMino -5-fluorine pyridine;3-AMINO-5-FLUOROPYRIDINE 97%
- CBNumber:
- CB6767921
- Molecular Formula:
- C5H5FN2
- Molecular Weight:
- 112.11
- MOL File:
- 210169-05-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/1 19:39:48
| Melting point | 86°C |
|---|---|
| Boiling point | 232.7±20.0 °C(Predicted) |
| Density | 1.257±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| form | powder to crystal |
| pka | 3.74±0.20(Predicted) |
| color | Light orange to Yellow to Green |
| CAS DataBase Reference | 210169-05-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 20/21/22-36/37/38-22 | |||||||||
| Safety Statements | 26-36-36/37 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2933399990 | |||||||||
| NFPA 704 |
|
3-Amino-5-fluoropyridine price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 732176 | 3-Amino-5-fluoropyridine | 210169-05-4 | 500MG | ₹11788.43 | 2022-06-14 | Buy |
| TCI Chemicals (India) | A2753 | 3-Amino-5-fluoropyridine min. 97.0 % | 210169-05-4 | 1G | ₹3700 | 2022-05-26 | Buy |
| TCI Chemicals (India) | A2753 | 3-Amino-5-fluoropyridine min. 97.0 % | 210169-05-4 | 5G | ₹13600 | 2022-05-26 | Buy |
3-Amino-5-fluoropyridine Chemical Properties,Uses,Production
Chemical Properties
Light yellow Crystal
Uses
3-amino-5-fluoropyridine is an important intermediate mainly used in medicine and organic synthesis. It is used to synthesize Ivosidenib. Ivosidenib is an isocitrate dehydrogenase-1 inhibitor used to treat acute myeloid leukemia and cholangiocarcinoma in adults.
Application
Reactant for:
Preparation of nonpeptide inhibitors of measles virus entry.
Preparation
synthesis of 3-Amino-5-fluoropyridine: A solution of 3-amino-2,4,6-tribromo-5-fluoropyridine (23c) (0.9 g, 2.6 mmol), triethylamine (1.1 cm3, 7.9 mmol), palladium catalyst (0.1 g of 5% Pd-C catalyst) and DCM (15 cm3) was hydrogenated on a Parr apparatus for 18 h. Water (20 cm3) was added and the mixture filtered and extracted into DCM. The DCM solution was dried (MgS04) and evaporated giving 3-amino-5-fluoropyridine (0.3 g, >95% ), m.p. 86 ·c (from DCM) (Found: C, 53.6; H, 4.6; N, 25.0. C5H5FN2 requires C, 53.6; H, 4.5 N, 25.0%);
IR spectrum no. 9; mass spectrum no. 5; nmr spectrum no. 29.
3-Amino-5-fluoropyridine Preparation Products And Raw materials
Raw materials
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Global( 319)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| SL Drugs and Pharmaceuticals Pvt. Ltd. | +91 (40) 6661-1133 | New Delhi, India | 2688 | 50 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| Vyas Bio Life Sciences Pvt. Ltd | -65546373 | Hyderabad, India | 1213 | 58 | Inquiry |
| Reax Chemicals | 08048372701Ext 416 | Hyderabad, India | 4223 | 58 | Inquiry |
| Oceanic Pharmachem Pvt. Ltd. | 91-22-42128600 | Maharashtra, India | 2006 | 58 | Inquiry |
| Biopharmacule Speciality Chemicals P Ltd (India) | +91 40 6462 1866 | Hyderabad, India | 526 | 58 | Inquiry |
| LABEX CORPORATION | 08068441104Ext 410 | Delhi, India | 117 | 58 | Inquiry |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
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3-AMINO-5-FLUOROPYRIDINE
3-Pyridinamine,5-fluoro-(9CI)
3-AMINO-5-FLUOROPYRIDINE 97%
5-Fluoropyridin-3-ylamine
3-Amine-5-fluoro-pyridin
3-AMine-5-fluoro-pyridine
3-PyridinaMine,5-fluoro-
3-aMino -5-fluorine pyridine
5-Fluoro-3-pyridinamine
3-AMINO-5-FLUOROPYRIDINE(RS20014327)
3-Amino-5-fluoropyridine >
3-AMINO-5-FLUOROPYRIDINE ISO 9001：2015 REACH
5-Fluoropyridin-3-amine
210169-05-4
210169-05-4
Fluorine series
Building Blocks
C5
C5 to C6
Chemical Synthesis
Fluorinated Building Blocks
Halogenated Heterocycles
Heterocyclic Building Blocks
Heterocyclic Fluorinated Building Blocks
Other Fluorinated Heterocycles
Pyridine series
Pyridines
Boronic Acid
PYRIDINE
AMINEPRIMARY
HALIDE