3-Amino-5-fluoropyridine
![3-Amino-5-fluoropyridine Structure](CAS/GIF/210169-05-4.gif)
- CAS No.
- 210169-05-4
- Chemical Name:
- 3-Amino-5-fluoropyridine
- Synonyms
- 5-Fluoropyridin-3-amine;5-Fluoro-3-pyridinamine;3-AMINO-5-FLUOROPYRIDINE;3-PyridinaMine,5-fluoro-;3-Amine-5-fluoro-pyridin;5-Fluoropyridin-3-ylamine;3-AMine-5-fluoro-pyridine;3-Amino-5-fluoropyridine >3-aMino -5-fluorine pyridine;3-AMINO-5-FLUOROPYRIDINE 97%
- CBNumber:
- CB6767921
- Molecular Formula:
- C5H5FN2
- Molecular Weight:
- 112.11
- MOL File:
- 210169-05-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/1 19:39:48
Melting point | 86°C |
---|---|
Boiling point | 232.7±20.0 °C(Predicted) |
Density | 1.257±0.06 g/cm3(Predicted) |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
form | powder to crystal |
pka | 3.74±0.20(Predicted) |
color | Light orange to Yellow to Green |
CAS DataBase Reference | 210169-05-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H302-H315-H319-H335 | |||||||||
Precautionary statements | P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 | |||||||||
Hazard Codes | Xi,Xn | |||||||||
Risk Statements | 20/21/22-36/37/38-22 | |||||||||
Safety Statements | 26-36-36/37 | |||||||||
WGK Germany | 3 | |||||||||
HazardClass | IRRITANT | |||||||||
HS Code | 2933399990 | |||||||||
NFPA 704 |
|
3-Amino-5-fluoropyridine price More Price(3)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 732176 | 3-Amino-5-fluoropyridine | 210169-05-4 | 500MG | ₹11788.43 | 2022-06-14 | Buy |
TCI Chemicals (India) | A2753 | 3-Amino-5-fluoropyridine min. 97.0 % | 210169-05-4 | 1G | ₹3700 | 2022-05-26 | Buy |
TCI Chemicals (India) | A2753 | 3-Amino-5-fluoropyridine min. 97.0 % | 210169-05-4 | 5G | ₹13600 | 2022-05-26 | Buy |
3-Amino-5-fluoropyridine Chemical Properties,Uses,Production
Chemical Properties
Light yellow Crystal
Uses
3-amino-5-fluoropyridine is an important intermediate mainly used in medicine and organic synthesis. It is used to synthesize Ivosidenib. Ivosidenib is an isocitrate dehydrogenase-1 inhibitor used to treat acute myeloid leukemia and cholangiocarcinoma in adults.
Application
Reactant for:
Preparation of nonpeptide inhibitors of measles virus entry.
Preparation
synthesis of 3-Amino-5-fluoropyridine: A solution of 3-amino-2,4,6-tribromo-5-fluoropyridine (23c) (0.9 g, 2.6 mmol), triethylamine (1.1 cm3, 7.9 mmol), palladium catalyst (0.1 g of 5% Pd-C catalyst) and DCM (15 cm3) was hydrogenated on a Parr apparatus for 18 h. Water (20 cm3) was added and the mixture filtered and extracted into DCM. The DCM solution was dried (MgS04) and evaporated giving 3-amino-5-fluoropyridine (0.3 g, >95% ), m.p. 86 ·c (from DCM) (Found: C, 53.6; H, 4.6; N, 25.0. C5H5FN2 requires C, 53.6; H, 4.5 N, 25.0%);
IR spectrum no. 9; mass spectrum no. 5; nmr spectrum no. 29.
3-Amino-5-fluoropyridine Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
SL Drugs and Pharmaceuticals Pvt. Ltd. | +91 (40) 6661-1133 | New Delhi, India | 2688 | 50 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
Vyas Bio Life Sciences Pvt. Ltd | -65546373 | Hyderabad, India | 1213 | 58 | Inquiry |
Reax Chemicals | 08048372701Ext 416 | Hyderabad, India | 4223 | 58 | Inquiry |
Oceanic Pharmachem Pvt. Ltd. | 91-22-42128600 | Maharashtra, India | 2006 | 58 | Inquiry |
Biopharmacule Speciality Chemicals P Ltd (India) | +91 40 6462 1866 | Hyderabad, India | 526 | 58 | Inquiry |
LABEX CORPORATION | 08068441104Ext 410 | Delhi, India | 117 | 58 | Inquiry |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
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